Integrin
Los inhibidores de integrinas se dirigen a las integrinas, una familia de receptores en la superficie celular que desempeñan un papel crucial en la adhesión celular, la migración y la transducción de señales. Las integrinas están involucradas en la regulación del ciclo celular, particularmente en procesos como la división y la diferenciación celular. Inhibir las integrinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y la apoptosis, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer y el estudio de la metástasis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de integrinas de alta calidad para apoyar su investigación en la regulación del ciclo celular, la biología del cáncer y el desarrollo terapéutico.
Se han encontrado 286 productos para "Integrin".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
EMD527040 hydrochloride
EMD527040 (hydrochloride) is a potent and selective αvβ6 antagonist with antifibrotic properties. It is applicable in research related to liver cancer and hepatic fibrosis.Forma y color:Odour SolidEchistatin TFA
Echistatin TFA: a minimal RGD protein from snake venom; inhibits platelet aggregation and bone resorption; targets αIIbβ3, αvβ3, α5β1.Forma y color:Odour SolidFibronectin CS1 Peptide
CAS:Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Fórmula:C38H64N8O15Pureza:98%Forma y color:SolidPeso molecular:872.96LDV-FITC TFA
LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.Fórmula:C69H81N11O17S·xC2HF3O2αvβ6-BP
αvβ6-BP is a selective αvβ6-binding peptide, useful for research in molecular imaging.Fórmula:C93H164N34O27Peso molecular:2189.25052Orbofiban acetate
CAS:Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administeredFórmula:C19H27N5O6Forma y color:SolidPeso molecular:421.45Arg-Gly-Glu-Ser TFA
Arg-Gly-Glu-Ser TFA, an RGD-related peptide, serves as a control for evaluating the inhibitory activity of RGDS on fibrinogen binding to activated platelets.Fórmula:C18H30F3N7O10Forma y color:SolidPeso molecular:561.47Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Fórmula:C21H29N5O6Pureza:99.57%Forma y color:SolidPeso molecular:447.48BRM/BRG1 ligand 3
CAS:BRM/BRG1 ligand 3 is a target protein ligand utilized in the synthesis of PROTAC BRM/BRG1 degrader-3.Fórmula:C19H24N6OForma y color:SolidPeso molecular:352.43Anti-Mouse CD3E Antibody (1E11.D)
Anti-Mouse CD3E Antibody (1E11.D) is an IgG1 antibody inhibitor targeting the mouse CD3E molecule.Forma y color:Odour LiquidSTX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Pureza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.12 kDaMORF-627
CAS:MORF-627 is an orally active selective inhibitor of integrin αvβ6 (integrinαvβ6), with an IC50 of 9.2 nM as measured in a human serum ligand binding assay. It effectively inhibits αvβ6-mediated activation of TGF-β1 with an IC50 of 2.63 nM and suppresses SMAD2/3 phosphorylation, showing an IC50 of 8.3 nM. Additionally, MORF-627 ameliorates bleomycin-induced pulmonary fibrosis in mice.Fórmula:C31H40FN3O4Forma y color:SolidPeso molecular:537.67BIO5192 hydrate
BIO5192 hydrate: potent α4β1 inhibitor, binds selectively (Kd<10 pM, IC50=1.8 nM), boosts murine HSPC mobilization 30x.Forma y color:SolidFibronectin Active Fragment Control
CAS:Fibronectin: a ~440kDa glycoprotein, binds integrins, collagen, fibrin, and heparan sulfate in the extracellular matrix.Fórmula:C18H32N8O9Pureza:98%Forma y color:SolidPeso molecular:504.49KGDS
CAS:KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1].Fórmula:C15H27N5O8Forma y color:SolidPeso molecular:405.4Lys-Gln-Ala-Gly-Asp-Val
CAS:KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.Fórmula:C25H44N8O10Forma y color:SolidPeso molecular:616.66Odulimomab
CAS:Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.Forma y color:LiquidGRGDSPK TFA
GRGDSPK TFA is an RGD peptide, competitive inhibitor of integrin-fibronectin, used to research integrins in bone dynamics.Fórmula:C30H50F3N11O13Forma y color:SolidPeso molecular:829.78Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Pureza:>95%Forma y color:LiquidPeso molecular:146.1 kDamP6
CAS:mP6 (Myr-FEEERA-OH), a myristoylated peptide, selectively inhibits Gα 13's interaction with integrin β 3 while preserving talin-dependent integrin function.Fórmula:C47H75N9O14Pureza:98%Forma y color:SolidPeso molecular:990.15
