Ferroptosis
La ferroptosis es una forma de muerte celular regulada caracterizada por la acumulación de peróxidos lipídicos y el estrés oxidativo dependiente de hierro. A diferencia de la apoptosis, la ferroptosis no está impulsada por caspasas, sino por el fallo de las defensas antioxidantes celulares, lo que conduce a la muerte celular. Los inhibidores e inductores de la ferroptosis son fundamentales para estudiar esta vía única de muerte celular, que está implicada en diversas enfermedades, como el cáncer, la neurodegeneración y el daño por isquemia-reperfusión. En CymitQuimica, ofrecemos una amplia gama de moduladores de la ferroptosis de alta calidad para apoyar su investigación en mecanismos de muerte celular, estrés oxidativo y patología de enfermedades.
Se han encontrado 226 productos de "Ferroptosis"
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ZX703
ZX703 is a protein hydrolysis-targeting chimera (PROTAC) that mediates the degradation of GPX4 through the ubiquitin-proteasome and autophagy-lysosome pathways, with a DC50 of 0.315 µM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby promoting ferroptosis in cancer cells.Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:Iron(III) compound induces ferroptosis in NB1 cells at 3μM, not apoptosis/necroptosis; inhibits various cancers, effective against drug-resistant NALM-6.Fórmula:C20H14ClFeN2O2Forma y color:SolidPeso molecular:405.64CQ-ER
CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).Fórmula:C33H33N7O6SForma y color:SolidPeso molecular:655.72W1131 TFA
W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.Fórmula:C25H20F3N5O6Pureza:98.1%Forma y color:SolidPeso molecular:543.45Ref: TM-T80847
1mg92,00€5mg188,00€10mg311,00€25mg628,00€50mg1.008,00€100mg1.596,00€1mL*10mM (DMSO)A consultar84-B10
CAS:84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.Fórmula:C25H22F3NO5Pureza:99.76%Forma y color:SolidPeso molecular:473.44Ref: TM-T75268
1mg49,00€5mg97,00€10mg160,00€25mg305,00€50mg472,00€100mg707,00€200mg938,00€1mL*10mM (DMSO)97,00€Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Pureza:98%Forma y color:Odour SolidGPX4-IN-7
<p>GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.</p>Fórmula:C25H23ClN4O4Pureza:98%Forma y color:SolidPeso molecular:478.93Ferroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A.Fórmula:C22H34O5Pureza:98%Forma y color:SolidPeso molecular:378.5Idebenone
CAS:Fórmula:C19H30O5Pureza:>98.0%(T)(HPLC)Forma y color:Light yellow to Brown powder to crystalPeso molecular:338.44Cerivastatin sodium
CAS:Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.Fórmula:C26H33FNNaO5Pureza:98.50% - 99.67%Forma y color:SolidPeso molecular:481.53CuATSP
CAS:CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.Fórmula:C18H18CuN6S2Pureza:97.09%Forma y color:SolidPeso molecular:446.05CuATSM
CAS:Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.Fórmula:C8H14CuN6S2Forma y color:SolidPeso molecular:321.92CCW16
CAS:CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.Fórmula:C22H20ClNO3Pureza:97%Forma y color:SolidPeso molecular:381.85BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Fórmula:C26H26F3N7O2Pureza:98% - 99.95%Forma y color:SolidPeso molecular:525.53Ref: TM-T2488
1mg35,00€2mg43,00€5mg63,00€10mg101,00€25mg212,00€50mg351,00€100mg588,00€1mL*10mM (DMSO)73,00€UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Fórmula:C25H38ClN5O2SPureza:99.62%Forma y color:SolidPeso molecular:508.12Ref: TM-T8662
1mgA consultar2mg49,00€5mg80,00€10mg111,00€25mg160,00€50mg202,00€100mg283,00€200mg419,00€1mL*10mM (DMSO)89,00€Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Fórmula:C15H12O6Forma y color:SolidPeso molecular:288.25TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Fórmula:C10H14O2Pureza:99.17% - 99.53%Forma y color:White Solid PowderPeso molecular:166.22Ferrostatin-1
CAS:Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!Fórmula:C15H22N2O2Pureza:96.1% - 99.68%Forma y color:SolidPeso molecular:262.35NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFórmula:C21H26N7Na4O17P3Pureza:97.15% - >99.99%Forma y color:SolidPeso molecular:833.35L-Glutamic acid monosodium salt
CAS:L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Fórmula:C5H8NO4·NaPureza:99.93%Forma y color:White Solid CrystallinePeso molecular:169.11Coenzyme Q10
CAS:Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.Fórmula:C59H90O4Pureza:99.14% - 99.88%Forma y color:DrypowderPeso molecular:863.34SP-420
CAS:SP-420 is a novel orally active iron chelator.Fórmula:C16H21NO6SPureza:99.39%Forma y color:SolidPeso molecular:355.41ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Forma y color:SolidPeso molecular:475.32Ref: TM-T8375
1mg35,00€2mg52,00€5mg87,00€10mg140,00€25mg246,00€50mg414,00€100mg557,00€1mL*10mM (DMSO)90,00€Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.8%Forma y color:Yellow SolidPeso molecular:441.54Ref: TM-T3170
2mg42,00€5mg62,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€1mL*10mM (DMSO)85,00€L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Fórmula:C8H18N2O3SPureza:97.07% - ≥98%Forma y color:White Fine PowderPeso molecular:222.31DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Fórmula:C8H18N2O3SPureza:98% - 99.64%Forma y color:White Fine PowderPeso molecular:222.31SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Fórmula:C26H32N4O2Pureza:97.73%Forma y color:SolidPeso molecular:432.56Ref: TM-T9073
1mg37,00€2mg52,00€5mg77,00€10mg114,00€25mg215,00€50mg324,00€100mg484,00€1mL*10mM (DMSO)94,00€Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Fórmula:C23H28O8Pureza:98.91% - 99.84%Forma y color:SolidPeso molecular:432.46Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Fórmula:C13H15NO2SPureza:99.76% - 99.94%Forma y color:White SolidPeso molecular:249.33Ref: TM-T1934
2mg35,00€5mg50,00€10mg66,00€25mg85,00€50mg124,00€100mg197,00€200mg255,00€1mL*10mM (DMSO)62,00€Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Fórmula:C18H28N2OPureza:99.72%Forma y color:SolidPeso molecular:288.43Ref: TM-T1787
5mg48,00€10mg63,00€25mg93,00€50mg136,00€100mg188,00€200mg283,00€500mg487,00€1mL*10mM (DMSO)49,00€Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Forma y color:SolidPeso molecular:340.85Ref: TM-T2376
1mg39,00€5mg85,00€10mg130,00€25mg244,00€50mg390,00€100mg495,00€200mg712,00€1mL*10mM (DMSO)85,00€Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFórmula:C14H8N2OPureza:97.63% - 99.82%Forma y color:SolidPeso molecular:220.23NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Forma y color:SolidPeso molecular:1142.12L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Fórmula:C6H12N2O4S2Pureza:99.59% - 99.85%Forma y color:White Solid PowderPeso molecular:240.30Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Forma y color:White To Off-White Crystalline PowderPeso molecular:357.43JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Forma y color:SolidPeso molecular:451.3Ref: TM-T37314
1mg52,00€5mg111,00€10mg173,00€25mg298,00€50mg464,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)124,00€L-Glutamic acid
CAS:L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!Fórmula:C5H9NO4Pureza:99.14% - 99.55%Forma y color:White Solid CrystallinePeso molecular:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Forma y color:SolidPeso molecular:511.59Ref: TM-T4360
5mg51,00€10mg79,00€25mg153,00€50mg243,00€100mg376,00€200mg562,00€500mg899,00€1mL*10mM (DMSO)59,00€Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Fórmula:C13H13N3OSPureza:99.25% - >99.99%Forma y color:SolidPeso molecular:259.33Ref: TM-T1847
5mg35,00€10mg49,00€25mg82,00€50mg113,00€100mg170,00€200mg250,00€500mg419,00€1mL*10mM (DMSO)52,00€Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFórmula:C30H32ClFN2OPureza:99.72% - >99.99%Forma y color:SolidPeso molecular:491.04Ref: TM-T1885
1mg60,00€2mg88,00€5mg111,00€10mg173,00€25mg354,00€50mg528,00€100mg743,00€1mL*10mM (DMSO)120,00€Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Fórmula:C32H43NO4Pureza:97.81% - 99.09%Forma y color:SolidPeso molecular:505.69Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Fórmula:C7H7NO2Pureza:97.585% - 99.49%Forma y color:Prisms Aqueous From Alcohol + Water SolidPeso molecular:137.14WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Fórmula:C28H38O6Pureza:97.41% - 99.99%Forma y color:SolidPeso molecular:470.60Ref: TM-T5687
1mg85,00€5mg265,00€10mg393,00€25mg653,00€50mg929,00€100mg1.254,00€500mg2.517,00€1mL*10mM (DMSO)304,00€PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Fórmula:C9H15NO3Pureza:99.22%Forma y color:SolidPeso molecular:185.22Ref: TM-T6954
5mg51,00€10mg73,00€25mg140,00€50mg207,00€100mg368,00€200mg547,00€500mg877,00€1mL*10mM (DMSO)57,00€Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Fórmula:C25H27N5O4Pureza:99.94% - >99.99%Forma y color:White PowderPeso molecular:461.51Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Fórmula:C18H21N5O2Pureza:99.63%Forma y color:SolidPeso molecular:339.39Ref: TM-T6192
2mg35,00€5mg52,00€10mg64,00€25mg86,00€50mg97,00€100mg136,00€200mg188,00€1mL*10mM (DMSO)52,00€Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Fórmula:C33H34FN2O5CaPureza:99.27% - >99.99%Forma y color:White Crystalline PowderPeso molecular:577.67Erastin
CAS:Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Fórmula:C30H31ClN4O4Pureza:98% - 99.75%Forma y color:SolidPeso molecular:547.04Ref: TM-T1765
1mg48,00€2x1mg63,00€5x1mg87,00€10x1mg127,00€25x1mg202,00€50x1mg300,00€100x1mg444,00€200x1mg652,00€Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Fórmula:C14H18O4Pureza:98.90% - 99.90%Forma y color:White To Fainly Beige Crystalline PowderPeso molecular:250.29FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Fórmula:C25H31N3O5S2Pureza:99.72% - 99.78%Forma y color:SolidPeso molecular:517.66Ref: TM-T4066
2mg42,00€5mg63,00€10mg89,00€25mg192,00€50mg341,00€100mg535,00€200mg748,00€1mL*10mM (DMSO)72,00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Fórmula:C19H18O8Pureza:97.43% - 98.4%Forma y color:SolidPeso molecular:374.34Ref: TM-TJS1159
1mg60,00€5mg127,00€10mg188,00€25mg348,00€50mg512,00€100mg730,00€500mg1.483,00€1mL*10mM (DMSO)226,00€Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Fórmula:C16H18N2OS·HBrPureza:97.71% - >99.99%Forma y color:SolidPeso molecular:367.3Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Fórmula:C16H17BrN2SPureza:99.24% - 99.74%Forma y color:SolidPeso molecular:349.29Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Fórmula:C19H22Cl2N4Forma y color:SolidPeso molecular:377.31L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Fórmula:C8H19ClN2O3SForma y color:SolidPeso molecular:258.77Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Fórmula:C18H28N2O·HClPureza:99.74%Forma y color:White Crystalline PowderPeso molecular:324.89Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Fórmula:C24H32Fe3N3O28Pureza:98%Forma y color:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaPeso molecular:978.05Pioglitazone potassium
CAS:Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.Fórmula:C19H19KN2O3SForma y color:SolidPeso molecular:394.53CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Forma y color:SolidPeso molecular:541.72Ref: TM-TQ0120
1mg37,00€5mg79,00€10mg111,00€25mg210,00€50mg338,00€100mg512,00€500mg1.093,00€1mL*10mM (DMSO)94,00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Fórmula:C29H40N2O3Pureza:97.50%Forma y color:Solid Off-WhitePeso molecular:464.64(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFórmula:C15H14O6Pureza:98.55% - 98.80%Forma y color:SolidPeso molecular:290.27CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Fórmula:C23H27N3O5S2Pureza:99.46% - 99.91%Forma y color:SolidPeso molecular:489.61Ref: TM-T4309
1mg37,00€2mg52,00€5mg79,00€10mg115,00€25mg188,00€50mg299,00€100mg459,00€1mL*10mM (DMSO)86,00€Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Fórmula:C34H32ClFeN4O4Pureza:97.169% - 99.59%Forma y color:Dark Purple Crystalline PowderPeso molecular:651.94DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFórmula:C15H24O2Pureza:99.06% - 99.17%Forma y color:SolidPeso molecular:236.35Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Fórmula:C15H20O3Pureza:98% - 99.8%Forma y color:SolidPeso molecular:248.32UAMC-3203
CAS:UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).Fórmula:C25H37N5O2SPureza:97.052% - 99.72%Forma y color:SolidPeso molecular:471.66Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Fórmula:C10H17NO3Pureza:98.75% - 99.57%Forma y color:SolidPeso molecular:199.25Ref: TM-T4414
5mg73,00€10mg105,00€25mg207,00€50mg368,00€100mg652,00€500mg1.320,00€1mL*10mM (DMSO)81,00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Fórmula:C5H10N2O3Pureza:99.99%Forma y color:White Or Off-White PowderPeso molecular:146.14RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Fórmula:C23H21ClN2O5Pureza:98% - 99.96%Forma y color:SolidPeso molecular:440.88Ref: TM-T3646
1g1.359,00€1mg39,00€2mg51,00€5mg79,00€10mg126,00€25mg258,00€50mg349,00€100mg459,00€500mg1.026,00€Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Fórmula:C17H19NO5Pureza:97.03% - 99.90%Forma y color:SolidPeso molecular:317.34DL-α-Tocopherol
CAS:<p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>Fórmula:C29H50O2Pureza:99.61% - 99.90%Forma y color:Light Yellow Liquid ViscousPeso molecular:430.71(E)-Ferulic acid
CAS:(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression ofFórmula:C10H10O4Pureza:99.63%Forma y color:SolidPeso molecular:194.18SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Fórmula:C22H28N2O2Pureza:98.58%Forma y color:SolidPeso molecular:352.47Ref: TM-T8922
1mg46,00€5mg80,00€10mg116,00€25mg227,00€50mg359,00€100mg550,00€500mg1.159,00€1mL*10mM (DMSO)105,00€Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Fórmula:C11H11NO4SPureza:98.71%Forma y color:SolidPeso molecular:253.27Ref: TM-T19692
1mg104,00€5mg235,00€10mg364,00€25mg582,00€50mg817,00€100mg1.121,00€1mL*10mM (DMSO)216,00€ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Forma y color:SolidPeso molecular:477.4Ref: TM-T8970
1mg46,00€5mg89,00€10mg116,00€25mg227,00€50mg354,00€100mg494,00€200mg708,00€1mL*10mM (DMSO)96,00€1R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Fórmula:C23H21ClN2O5Pureza:99.51%Forma y color:SolidPeso molecular:440.88Ref: TM-T9561
1mg90,00€5mg187,00€10mg280,00€25mg452,00€50mg640,00€100mg843,00€200mg1.130,00€1mL*10mM (DMSO)217,00€Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Fórmula:C35H41ClN6O4Pureza:99.52%Forma y color:SolidPeso molecular:645.19Ref: TM-T16540
1mg96,00€5mg168,00€10mg283,00€25mg567,00€50mg929,00€100mg1.225,00€200mg1.681,00€500mg2.498,00€PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Forma y color:SolidPeso molecular:237.32Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Fórmula:C21H19ClN4O2Pureza:93.468% - 99.31%Forma y color:SolidPeso molecular:394.85Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Fórmula:C14H15N5SPureza:99% - 99.02%Forma y color:SolidPeso molecular:285.37Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Fórmula:C18H22O4Pureza:97.82% - 99.91%Forma y color:SolidPeso molecular:302.36FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Fórmula:C15H28O3Pureza:97.27%Forma y color:SoildPeso molecular:256.38Frataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Fórmula:C20H23NO6Pureza:99.34%Peso molecular:373.4Microtubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Fórmula:C21H15N3O2SForma y color:SolidPeso molecular:373.43Anti-Mouse IL-1b Antibody (B122)
Anti-Mouse IL-1b Antibody (B122) is a mab inhibitor, blocks IL-1β signaling, reducing monocyte infiltration and alleviating T cell exhaustion.Forma y color:Odour LiquidPioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Fórmula:C19H20N2O3SPureza:98%Forma y color:SolidPeso molecular:360.46IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Fórmula:C21H28N4O2Forma y color:SolidPeso molecular:368.47Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFórmula:C32H40BrN3O2Pureza:98%Forma y color:SolidPeso molecular:578.58Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Fórmula:C17H24ClN3O2Peso molecular:337.84W1131
CAS:W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Fórmula:C23H19N5O4Forma y color:SolidPeso molecular:429.43Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Fórmula:C22H19N3O5Forma y color:SolidPeso molecular:405.4CGP 65015
CAS:CGP 65015 is an oral iron chelator and can mobilize iron deposits.Fórmula:C14H15NO4Pureza:98%Forma y color:SolidPeso molecular:261.27Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Fórmula:C25H21ClN2O5Forma y color:SolidPeso molecular:464.9NPD4928
CAS:NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Fórmula:C29H32N2O6Forma y color:SolidPeso molecular:504.57CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Forma y color:SolidPeso molecular:295.76YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.Fórmula:C25H26N6OForma y color:SolidPeso molecular:426.51Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Fórmula:C36H35ClN4O4Pureza:99.63%Forma y color:SolidPeso molecular:623.14HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Fórmula:C20H24N2O6Pureza:97.35% - 98.58%Forma y color:SolidPeso molecular:388.41BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Fórmula:C23H19Cl2N3OSPureza:99.49%Forma y color:SolidPeso molecular:456.39
![Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT37851.webp&w=3840&q=75)
