Ferroptosis
La ferroptosis es una forma de muerte celular regulada caracterizada por la acumulación de peróxidos lipídicos y el estrés oxidativo dependiente de hierro. A diferencia de la apoptosis, la ferroptosis no está impulsada por caspasas, sino por el fallo de las defensas antioxidantes celulares, lo que conduce a la muerte celular. Los inhibidores e inductores de la ferroptosis son fundamentales para estudiar esta vía única de muerte celular, que está implicada en diversas enfermedades, como el cáncer, la neurodegeneración y el daño por isquemia-reperfusión. En CymitQuimica, ofrecemos una amplia gama de moduladores de la ferroptosis de alta calidad para apoyar su investigación en mecanismos de muerte celular, estrés oxidativo y patología de enfermedades.
Se han encontrado 225 productos de "Ferroptosis"
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(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFórmula:C15H14O6Pureza:98.55% - 98.80%Forma y color:SolidPeso molecular:290.27CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Fórmula:C23H27N3O5S2Pureza:99.46% - 99.91%Forma y color:SolidPeso molecular:489.61Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Fórmula:C34H32ClFeN4O4Pureza:97.169% - 99.59%Forma y color:Dark Purple Crystalline PowderPeso molecular:651.94DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFórmula:C15H24O2Pureza:99.06% - 99.17%Forma y color:SolidPeso molecular:236.35Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Fórmula:C15H20O3Pureza:98% - 99.8%Forma y color:SolidPeso molecular:248.32UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Fórmula:C25H37N5O2SPureza:97.052% - 99.72%Forma y color:SolidPeso molecular:471.66Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Fórmula:C10H17NO3Pureza:98.75% - 99.57%Forma y color:SolidPeso molecular:199.25D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Fórmula:C5H10N2O3Pureza:99.99%Forma y color:White Or Off-White PowderPeso molecular:146.14RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Fórmula:C23H21ClN2O5Pureza:98% - 99.96%Forma y color:SolidPeso molecular:440.88Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Fórmula:C17H19NO5Pureza:97.03% - 99.90%Forma y color:SolidPeso molecular:317.34DL-α-Tocopherol
CAS:<p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>Fórmula:C29H50O2Pureza:99.61% - 99.90%Forma y color:Light Yellow Liquid ViscousPeso molecular:430.71(E)-Ferulic acid
CAS:(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression ofFórmula:C10H10O4Pureza:99.63%Forma y color:SolidPeso molecular:194.18SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Fórmula:C22H28N2O2Pureza:98.58%Forma y color:SolidPeso molecular:352.47Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Fórmula:C11H11NO4SPureza:98.71%Forma y color:SolidPeso molecular:253.27ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Forma y color:SolidPeso molecular:477.41R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Fórmula:C23H21ClN2O5Pureza:99.51%Forma y color:SolidPeso molecular:440.88PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Forma y color:SolidPeso molecular:237.32Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Fórmula:C35H41ClN6O4Pureza:99.52%Forma y color:SolidPeso molecular:645.19Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Fórmula:C21H19ClN4O2Pureza:93.468% - 99.31%Forma y color:SolidPeso molecular:394.85Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Fórmula:C14H15N5SPureza:99% - 99.02%Forma y color:SolidPeso molecular:285.37
