Ferroptosis
La ferroptosis es una forma de muerte celular regulada caracterizada por la acumulación de peróxidos lipídicos y el estrés oxidativo dependiente de hierro. A diferencia de la apoptosis, la ferroptosis no está impulsada por caspasas, sino por el fallo de las defensas antioxidantes celulares, lo que conduce a la muerte celular. Los inhibidores e inductores de la ferroptosis son fundamentales para estudiar esta vía única de muerte celular, que está implicada en diversas enfermedades, como el cáncer, la neurodegeneración y el daño por isquemia-reperfusión. En CymitQuimica, ofrecemos una amplia gama de moduladores de la ferroptosis de alta calidad para apoyar su investigación en mecanismos de muerte celular, estrés oxidativo y patología de enfermedades.
Se han encontrado 215 productos de "Ferroptosis"
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W1131
CAS:<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Fórmula:C23H19N5O4Forma y color:SolidPeso molecular:429.43YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Fórmula:C25H26N6OForma y color:SolidPeso molecular:426.51Ferroptosis inducer-1
CAS:<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Fórmula:C25H21ClN2O5Forma y color:SolidPeso molecular:464.9CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Forma y color:SolidPeso molecular:295.76Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Forma y color:SolidPeso molecular:578.58Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Fórmula:C22H19N3O5Forma y color:SolidPeso molecular:405.4IM-93
CAS:<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Fórmula:C21H28N4O2Forma y color:SolidPeso molecular:368.47CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Forma y color:SolidPeso molecular:261.27FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Fórmula:C22H27F3N4O2SPureza:99.44%Forma y color:SolidPeso molecular:468.54Deferitazole
CAS:<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Fórmula:C18H25NO7SPureza:99.48%Forma y color:SolidPeso molecular:399.46Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Fórmula:C36H35ClN4O4Pureza:99.63%Forma y color:SolidPeso molecular:623.14HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Fórmula:C20H24N2O6Pureza:97.35% - 98.58%Forma y color:SolidPeso molecular:388.41BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Fórmula:C23H19Cl2N3OSPureza:99.49%Forma y color:SolidPeso molecular:456.39Lepadin E
CAS:<p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>Fórmula:C26H47NO3Pureza:98%Forma y color:SolidPeso molecular:421.66CP-24879 hydrochloride
CAS:<p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>Fórmula:C11H18ClNOPureza:98.08%Forma y color:SolidPeso molecular:215.72Docebenone
CAS:<p>Docebenone is a selective and orally active inhibitor of 5-LO.</p>Fórmula:C21H26O3Forma y color:SolidPeso molecular:326.43Ferroptocide
CAS:<p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>Fórmula:C30H36ClN3O7Forma y color:SolidPeso molecular:586.08Ogremorphin
CAS:<p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>Fórmula:C21H17N3OSPureza:99.65% - 99.65%Forma y color:SolidPeso molecular:359.44Lepadin H
CAS:<p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>Fórmula:C26H45NO3Pureza:98%Forma y color:SolidPeso molecular:419.64viFSP1
CAS:<p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>Fórmula:C16H17N3O3SForma y color:SolidPeso molecular:331.39
