Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 284 productos de "Asociado a microtúbulos"
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ST-401
CAS:ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.Fórmula:C24H20N2OForma y color:SolidPeso molecular:352.434-Desacetylvinblastine hydrazide
CAS:Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.Fórmula:C43H56N6O7Forma y color:SolidPeso molecular:768.94Semorinemab
CAS:Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.Pureza:95% - 96.7% (SDS-PAGE); 97.2% (SEC-HPLC)Forma y color:LiquidGosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Pureza:95% - 95%Forma y color:LiquidPosdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Forma y color:LiquidTubulin polymerization-IN-2
CAS:Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.Fórmula:C17H12F2N2O2Forma y color:SolidPeso molecular:314.29Auristatin F
CAS:Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.Fórmula:C40H67N5O8Pureza:98.41% - 99.25%Forma y color:SolidPeso molecular:745.99Tubulin polymerization-IN-37
CAS:Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.Fórmula:C19H20N2O4Forma y color:SolidPeso molecular:340.37Microtubule inhibitor 5
CAS:Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.Fórmula:C22H15FN2O4Forma y color:SolidPeso molecular:390.36Tubulin polymerization-IN-27
CAS:Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.Fórmula:C22H20N2O2Forma y color:SolidPeso molecular:344.41Tubulin inhibitor 26
CAS:Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.Fórmula:C17H19N3O3Forma y color:SolidPeso molecular:313.35Tubulin inhibitor 20
CAS:Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].Fórmula:C19H18O4Forma y color:SolidPeso molecular:310.34Amphethinile
CAS:Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.Fórmula:C15H11N3SPureza:98%Forma y color:SolidPeso molecular:265.33OSIP-486823
CAS:OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Fórmula:C29H28FNO4Pureza:98.59%Forma y color:SolidPeso molecular:473.54AMXI-5001
CAS:AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.Fórmula:C25H20FN5O3Forma y color:SolidPeso molecular:457.46SB26019
CAS:SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.Fórmula:C24H20O4Forma y color:SolidPeso molecular:372.41Anticancer agent 60
CAS:Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.Fórmula:C27H33N5O4SForma y color:SolidPeso molecular:523.65DJ101
CAS:DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.Fórmula:C23H20N4O3Pureza:98%Forma y color:SolidPeso molecular:400.43Tubulin polymerization-IN-19
CAS:Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.Fórmula:C25H25NO5Forma y color:SolidPeso molecular:419.47Antitumor agent-68
CAS:Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.Fórmula:C17H11NO2Forma y color:SolidPeso molecular:261.27
