Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 284 productos de "Asociado a microtúbulos"
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Deox B 7,4
CAS:Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.Fórmula:C18H18O5Forma y color:SolidPeso molecular:314.33Tubulin inhibitor 20
CAS:Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].Fórmula:C19H18O4Forma y color:SolidPeso molecular:310.34Tubulin inhibitor 26
CAS:Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.Fórmula:C17H19N3O3Forma y color:SolidPeso molecular:313.35Microtubule inhibitor 5
CAS:Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.Fórmula:C22H15FN2O4Forma y color:SolidPeso molecular:390.36Tubulin polymerization-IN-37
CAS:Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.Fórmula:C19H20N2O4Forma y color:SolidPeso molecular:340.37THK-5117
CAS:THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.Fórmula:C19H19FN2O2Forma y color:SolidPeso molecular:326.36OXi8007
CAS:OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.Fórmula:C26H24NNa2O10PForma y color:SolidPeso molecular:587.428Iso-Fludelone
CAS:Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.Fórmula:C27H36F3NO6Forma y color:SolidPeso molecular:527.57Tubulin polymerization-IN-18
CAS:Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.Fórmula:C25H25NO6Forma y color:SolidPeso molecular:435.47O-GlcNAcase-IN-4
CAS:O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.Fórmula:C16H22FN5O3SForma y color:SolidPeso molecular:383.44Antitumor agent-68
CAS:Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.Fórmula:C17H11NO2Forma y color:SolidPeso molecular:261.27Tubulin polymerization-IN-16
CAS:Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.Fórmula:C24H27N5O5Forma y color:SolidPeso molecular:465.5Tubulin polymerization-IN-36
CAS:Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.Fórmula:C18H18N2O3Forma y color:SolidPeso molecular:310.35Antitumor agent-71
CAS:Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.Fórmula:C26H31N5O4SForma y color:SolidPeso molecular:509.62Neuroinflammatory-IN-3
CAS:Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.Fórmula:C19H19ClO3Forma y color:SolidPeso molecular:330.81CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Fórmula:C14H9N3OPureza:98.38%Forma y color:SolidPeso molecular:235.24Ref: TM-T10704
1mg77,00€5mg170,00€10mg259,00€25mg507,00€50mg775,00€100mg1.054,00€1mL*10mM (DMSO)182,00€Tubulin polymerization-IN-10
CAS:Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.Fórmula:C18H21NO6SForma y color:SolidPeso molecular:379.43S516
CAS:S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.Fórmula:C21H19N5O4SPureza:98%Forma y color:SolidPeso molecular:437.47Tubulin polymerization-IN-21
CAS:Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.Fórmula:C30H29NO7Forma y color:SolidPeso molecular:515.55Tubulin inhibitor 27
CAS:DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.Fórmula:C21H19NO4Forma y color:SolidPeso molecular:349.38
