PKC
Los inhibidores de la proteína quinasa C (PKC) se dirigen a la familia de quinasas serina/treonina PKC, que están involucradas en una amplia gama de procesos celulares, incluidos la regulación del ciclo celular, la apoptosis y la diferenciación. La PKC desempeña un papel clave en las vías de transducción de señales que influyen en la proliferación y supervivencia celular. Inhibir la PKC puede provocar cambios en la progresión del ciclo celular, lo que hace que estos inhibidores sean valiosos en la investigación relacionada con el cáncer, la neurobiología y las enfermedades cardiovasculares. En CymitQuimica, ofrecemos una selección diversa de inhibidores de PKC de alta calidad para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.
Se han encontrado 102 productos de "PKC"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Mitoxantrone dihydrochloride
CAS:<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>Fórmula:C22H30Cl2N4O6Pureza:97.05% - >99.99%Forma y color:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Delcasertib
CAS:<p>Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).</p>Fórmula:C120H199N45O34S2Pureza:99.96%Forma y color:SolidPeso molecular:2880.28CMPD101
CAS:<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Fórmula:C24H21F3N6OPureza:99.01% - 99.04%Forma y color:SolidPeso molecular:466.46N-Desmethyltamoxifen hydrochloride
CAS:<p>N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.</p>Fórmula:C25H28ClNOPureza:99.15%Forma y color:SolidPeso molecular:393.95PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Pureza:95.42%Forma y color:SoildBisindolylmaleimide VIII acetate
CAS:<p>Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.</p>Fórmula:C26H26N4O4Pureza:99.27%Forma y color:SolidPeso molecular:458.51Aurothiomalate tetramer sodium
<p>Aurothiomalate tetramer sodium, a tetrameric form of Aurothiomalate sodium, functions as an anti-arthritis gold agent. It also acts as a potent and selective inhibitor of the oncogenic PKCι signaling pathway.</p>Forma y color:Odour SolidProtein Kinase C (19-31) (TFA)(121545-65-1,free)
<p>Protein Kinase C (19-31) TFA is a serine-modified PKCa-derived inhibitor for testing PKC activity.</p>Fórmula:C69H119F3N26O18Pureza:98%Forma y color:SolidPeso molecular:1657.84PKCδ Peptide Substrate
CAS:<p>PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) and</p>Fórmula:C109H191N35O29SForma y color:SolidPeso molecular:2487.97Protein kinase C α peptide TFA
CAS:<p>Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.</p>Fórmula:C68H115F3N24O26SForma y color:SolidPeso molecular:1773.85NPC-15437 dihydrochloride
CAS:<p>NPC-15437 dihydrochloride is a PKC inhibitor blocking enzyme activity and phorbol ester binding, selective over other kinases, in cellular signaling research.</p>Fórmula:C25H52Cl2N4O2Forma y color:SolidPeso molecular:511.62K-252b
CAS:<p>K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.</p>Fórmula:C26H19N3O5Pureza:98%Forma y color:Ready-To-Use SolutionPeso molecular:453.45SAMβA TFA
<p>SAMβA TFA, a selective antagonist of Mfn1-βIIPKC association conjugated to the cell permeable peptide TAT47-57, is a rationally designed inhibitor that improves</p>Fórmula:C50H73N17O16·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:1168.22 (free acid)Ac-MBP (1-11)
CAS:<p>Ac-MBP 1-11, a primary encephalitogenic epitope in myelin basic protein (MBP), is a dominant short peptide sequence[1].</p>Fórmula:C2H3K2OPS3Pureza:98%Forma y color:SolidPeso molecular:248.411-Oleoyl-2-acetyl-sn-glycerol
CAS:<p>1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.</p>Fórmula:C23H42O5Forma y color:SolidPeso molecular:398.58Delcasertib acetate
<p>Delcasertib acetate is a selective δ protein kinase C (δPKC) inhibitor for the study of acute myocardial infarction and pain.</p>Fórmula:C122H203N45O36S2Pureza:98.92%Forma y color:SolidPeso molecular:2940.33Bisindolylmaleimide III
CAS:<p>Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6</p>Fórmula:C23H20N4O2Pureza:98.6%Forma y color:SolidPeso molecular:384.43Protein kinase inhibitor H-7
CAS:<p>H-7: potent PKC inhibitor with 6 μM Ki, also blocks cyclic nucleotide-dependent kinases.</p>Fórmula:C14H17N3O2SPureza:99.91%Forma y color:SoildPeso molecular:291.37Sangivamycin
CAS:<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Fórmula:C12H15N5O5Pureza:99.85%Forma y color:SolidPeso molecular:309.28Protein Kinase C (19-31)
CAS:<p>Protein Kinase C (19-31), a PKC inhibitor derived from PKCa, has a serine at position 25 and tests PKC activity.</p>Fórmula:C67H118N26O16Pureza:98%Forma y color:Lyophilized PowderPeso molecular:1543.82(8R)-8-Hydroxyepoxyboetirane A
<p>(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.</p>Forma y color:Odour SolidMyelin Basic Protein
CAS:<p>Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.</p>Fórmula:C60H103N21O17Pureza:98%Forma y color:SolidPeso molecular:1390.59ZIP
CAS:<p>Novel inhibitor for PKMζ, halts synaptic potentiation and reverses LTP with IC50 of 1-2.5 μM, erasing spatial memory.</p>Fórmula:C90H154N30O17Pureza:98%Forma y color:SolidPeso molecular:1928.4[Ala113]MBP(104-118)
CAS:<p>Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).</p>Fórmula:C67H104N20O19Pureza:98%Forma y color:SolidPeso molecular:1493.68PKCiota-IN-2
CAS:<p>PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).</p>Fórmula:C24H21N5OPureza:98.86%Forma y color:SolidPeso molecular:395.46[Ala107]MBP(104-118)
CAS:<p>Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).</p>Fórmula:C67H104N20O19Pureza:98%Forma y color:SolidPeso molecular:1493.68Neuropeptide DF2
CAS:<p>Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish.</p>Fórmula:C44H67N15O10Pureza:98%Forma y color:SolidPeso molecular:966.1Psychosine
CAS:<p>Psychosine (Galactosylsphingosine) is a PKC inhibitor, and is highly cytotoxic, inducing cell death in a variety of cells.</p>Fórmula:C24H47NO7Pureza:98%Forma y color:White PowderPeso molecular:461.63Pep2m, myristoylated
CAS:<p>Myristoylated pep2m peptide; inhibits GluA2-NSF interaction, reducing AMPA receptor function and surface expression.</p>Fórmula:C63H118N18O14SPureza:98%Forma y color:SolidPeso molecular:1383.8Protein Kinase C (19-36)
CAS:<p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>Fórmula:C93H159N35O24Pureza:98%Forma y color:SolidPeso molecular:2151.48PKC β pseudosubstrate
CAS:<p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>Fórmula:C177H294N62O38S3Pureza:98%Forma y color:SolidPeso molecular:3994.84Fasudil
CAS:<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Forma y color:SolidPeso molecular:291.37Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS:<p>Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.</p>Fórmula:C56H110N22O14Pureza:98%Forma y color:SolidPeso molecular:1315.61LY 379196
<p>LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.</p>Fórmula:C30H34N4O5SForma y color:SolidPeso molecular:562.68Protein kinase inhibitor H-7 dihydrochloride
CAS:<p>Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.</p>Fórmula:C14H19Cl2N3O2SPureza:99.54%Forma y color:White Crystalline SolidPeso molecular:364.29(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Fórmula:C39H72O5Forma y color:SolidPeso molecular:620.99PKC-θ inhibitor
CAS:<p>PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.</p>Fórmula:C20H25F3N6O3Pureza:99.46%Forma y color:SolidPeso molecular:454.45Hispidin
CAS:<p>Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties</p>Fórmula:C13H10O5Pureza:98.27%Forma y color:White Crystalline PowderPeso molecular:246.22PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Fórmula:C21H22N6OPureza:98.82%Forma y color:SolidPeso molecular:374.44Taurochenodeoxycholic Acid
CAS:<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Fórmula:C26H45NO6SPureza:99.53% - 99.86%Forma y color:SolidPeso molecular:499.7Valrubicin
CAS:<p>Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.</p>Fórmula:C34H36F3NO13Pureza:98.63%Forma y color:SolidPeso molecular:723.64Go 6983
CAS:<p>Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!</p>Fórmula:C26H26N4O3Pureza:98.41% - 99.85%Forma y color:SolidPeso molecular:442.51Darovasertib
CAS:<p>Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).</p>Fórmula:C22H23F3N8OPureza:98.72% - ≥95%Forma y color:SolidPeso molecular:472.47Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Forma y color:White To Off-White PowderPeso molecular:521.68Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Forma y color:White SolidPeso molecular:327.83Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Fórmula:C29H36O15Pureza:97.46% - 99.55%Forma y color:SolidPeso molecular:624.59Phorbol 12-myristate 13-acetate
CAS:<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Fórmula:C36H56O8Pureza:98.55% - >99.99%Forma y color:White To Off-White SolidPeso molecular:616.83Afuresertib hydrochloride
CAS:<p>Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)</p>Fórmula:C18H18Cl3FN4OSPureza:99.96%Forma y color:SolidPeso molecular:463.8TAS-301
CAS:<p>TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.</p>Fórmula:C23H19NO3Pureza:99.55%Forma y color:SolidPeso molecular:357.4Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Forma y color:SolidPeso molecular:570.64Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14Sotrastaurin
CAS:<p>Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).</p>Fórmula:C25H22N6O2Pureza:98% - 99.70%Forma y color:SolidPeso molecular:438.48Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Fórmula:C19H20O5Pureza:97.22% - 99.84%Forma y color:SolidPeso molecular:328.36Ζ-Stat
CAS:<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Fórmula:C10H8O10S3Pureza:99.85%Forma y color:SolidPeso molecular:384.36Chelerythrine chloride
CAS:<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Fórmula:C21H18ClNO4Pureza:95% - 99.19%Forma y color:Yellow To Orange SolidPeso molecular:383.83R59949
CAS:<p>R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.</p>Fórmula:C28H25F2N3OSPureza:97.04%Forma y color:SolidPeso molecular:489.58Taurolithocholic acid sodium salt
CAS:<p>Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but</p>Fórmula:C26H44NNaO5SPureza:99.79% - 99.93%Forma y color:SolidPeso molecular:505.69Desmethylglycitein
CAS:<p>Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has</p>Fórmula:C15H10O5Pureza:97.93%Forma y color:SolidPeso molecular:270.24Hypocrellin A
CAS:<p>Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.</p>Fórmula:C30H26O10Pureza:98% - 99.81%Forma y color:SolidPeso molecular:546.52Bisindolylmaleimide V
CAS:<p>Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.</p>Fórmula:C21H15N3O2Pureza:90%Forma y color:Red SolidPeso molecular:341.36Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Forma y color:Off-White PowderPeso molecular:466.531,2-Dimyristoyl-sn-glycerol
CAS:<p>1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..</p>Fórmula:C31H60O5Pureza:99.96%Forma y color:White Powder With LumpsPeso molecular:512.81HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Fórmula:C13H15N3O2SPureza:99.44%Forma y color:Pale Yellow Crystalline SolidPeso molecular:277.34Bisindolylmaleimide I
CAS:<p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>Fórmula:C25H24N4O2Pureza:98.19% - 98.75%Forma y color:Orange SolidPeso molecular:412.48Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Fórmula:C22H28N4O6Pureza:96.29% - 98.74%Forma y color:Blue PowderPeso molecular:444.48PKC-θ inhibitor hcl
CAS:<p>PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).</p>Fórmula:C20H26ClF3N6O3Pureza:98.93%Forma y color:SolidPeso molecular:490.91Aurothiomalate sodium
CAS:<p>Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.</p>Fórmula:C4H3AuNa2O4SPureza:99.66%Forma y color:SoildPeso molecular:390.07Decursinol angelate
CAS:<p>Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.</p>Fórmula:C19H20O5Pureza:99.93%Forma y color:SolidPeso molecular:328.36Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Forma y color:Orange To Brown PowderPeso molecular:516.54D-ERYTHRO-SPHINGOSINE
CAS:<p>D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator</p>Fórmula:C18H37NO2Pureza:98% - 99.85%Forma y color:SolidPeso molecular:299.49Procyanidin A1
CAS:<p>Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.</p>Fórmula:C30H24O12Pureza:99.52%Forma y color:SolidPeso molecular:576.5Afuresertib
CAS:<p>Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic</p>Fórmula:C18H17Cl2FN4OSPureza:97.51% - 99.51%Forma y color:SolidPeso molecular:427.32Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Fórmula:C20H13N3O2Pureza:98.83%Forma y color:Dark Red SolidPeso molecular:327.34TPPB
CAS:<p>TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).</p>Fórmula:C27H30F3N3O3Pureza:97.71% - 98.00%Forma y color:SolidPeso molecular:501.54Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Fórmula:C25H23N5O2S·CH4O3SPureza:98.79% - 99.02%Forma y color:SolidPeso molecular:553.65Ingenol
CAS:<p>Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.</p>Fórmula:C20H28O5Pureza:99.78% - 99.87%Forma y color:SolidPeso molecular:348.43PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Fórmula:C24H21N5O2Pureza:99.33%Forma y color:SolidPeso molecular:411.46Protein Kinase C 19-31 acetate
<p>PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.</p>Fórmula:C69H122N26O18Pureza:>99.99%Forma y color:SolidPeso molecular:1603.9Hypericin
CAS:<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Fórmula:C30H16O8Pureza:99.05% - ≥98%Forma y color:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44Enzastaurin
CAS:<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Fórmula:C32H29N5O2Pureza:98% - >99.99%Forma y color:SolidPeso molecular:515.6Ruboxistaurin hydrochloride
CAS:<p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>Fórmula:C28H28N4O3·HClPureza:98.44% - 99.22%Forma y color:SolidPeso molecular:505.01Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Fórmula:C41H70CaO9Pureza:98% - 98.11%Forma y color:SolidPeso molecular:747.07Phorbol 12,13-dibutyrate
CAS:<p>Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.</p>Fórmula:C28H40O8Pureza:99.32% - 99.37%Forma y color:SolidPeso molecular:504.61CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Fórmula:C18H18ClN5OPureza:98.81%Forma y color:SolidPeso molecular:355.82PS315
CAS:<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Fórmula:C23H19ClO2Pureza:98%Forma y color:SolidPeso molecular:362.85SC-10
CAS:<p>SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.</p>Fórmula:C17H22ClNO2SPureza:99.24% - 99.58%Forma y color:SolidPeso molecular:339.88AJH-836
CAS:<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Fórmula:C22H38O5Pureza:98%Forma y color:SolidPeso molecular:382.53NSC668394
CAS:<p>NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.</p>Fórmula:C17H12Br2N2O3Pureza:99.29% - 99.29%Forma y color:SolidPeso molecular:452.1DCPLA-ME
CAS:<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Fórmula:C21H38O2Pureza:99.80%Forma y color:SolidPeso molecular:322.53TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Fórmula:C27H25F3N4O4Pureza:99.39% - ≥98%Forma y color:SolidPeso molecular:526.51(-)-Indolactam V
CAS:<p>(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.</p>Fórmula:C17H23N3O2Pureza:98%Forma y color:SolidPeso molecular:301.38VTX-27
CAS:<p>VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).</p>Fórmula:C20H24ClFN6OPureza:99.84%Forma y color:SolidPeso molecular:418.9PKC-θ inhibitor 1
CAS:<p>PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)</p>Fórmula:C17H15F3N4OPureza:98%Forma y color:SolidPeso molecular:348.32PKC-IN-1
CAS:<p>PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,</p>Fórmula:C25H37FN8O2Pureza:98% - 98.79%Forma y color:SolidPeso molecular:500.61PKCTheta-IN-2
CAS:<p>PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.</p>Fórmula:C24H23N5O2Forma y color:SolidPeso molecular:413.47Dioleyl phosphatidylserine
CAS:<p>Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.</p>Fórmula:C42H78NO10PForma y color:SolidPeso molecular:788.04AS2521780
CAS:<p>AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).</p>Fórmula:C30H41N7OSPureza:98%Forma y color:SolidPeso molecular:547.76Cercosporin
CAS:<p>Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).</p>Fórmula:C29H26O10Pureza:98%Forma y color:SolidPeso molecular:534.5120-HETE
CAS:<p>20-HETE is a CYP450 product, vasoconstrictor, modulates K+ channels, affects NADPH, ROS, NF-κB, NO synthase, and cell apoptosis/proliferation.</p>Fórmula:C20H32O3Pureza:99.79%Forma y color:SolidPeso molecular:320.47
![[Ala113]MBP(104-118)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1888.webp&w=3840&q=75)
![[Ala107]MBP(104-118)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1887.webp&w=3840&q=75)
