PKC
Los inhibidores de la proteína quinasa C (PKC) se dirigen a la familia de quinasas serina/treonina PKC, que están involucradas en una amplia gama de procesos celulares, incluidos la regulación del ciclo celular, la apoptosis y la diferenciación. La PKC desempeña un papel clave en las vías de transducción de señales que influyen en la proliferación y supervivencia celular. Inhibir la PKC puede provocar cambios en la progresión del ciclo celular, lo que hace que estos inhibidores sean valiosos en la investigación relacionada con el cáncer, la neurobiología y las enfermedades cardiovasculares. En CymitQuimica, ofrecemos una selección diversa de inhibidores de PKC de alta calidad para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.
Se han encontrado 124 productos de "PKC"
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Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Fórmula:C26H45NO6SPureza:99.53% - 99.86%Forma y color:SolidPeso molecular:499.7Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Fórmula:C34H36F3NO13Pureza:98.63%Forma y color:SolidPeso molecular:723.64Go 6983
CAS:Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!Fórmula:C26H26N4O3Pureza:98.41% - 99.85%Forma y color:SolidPeso molecular:442.51Ref: TM-T6313
1mg40,00€2mg52,00€5mg79,00€10mg119,00€25mg233,00€50mg368,00€100mg533,00€1mL*10mM (DMSO)84,00€Darovasertib
CAS:Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Fórmula:C22H23F3N8OPureza:98.72% - ≥95%Forma y color:SolidPeso molecular:472.47Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Fórmula:C26H44NNaO6SPureza:98.23% - 99.56%Forma y color:White To Off-White PowderPeso molecular:521.68Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Forma y color:White SolidPeso molecular:327.83Verbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Fórmula:C29H36O15Pureza:97.46% - 99.55%Forma y color:SolidPeso molecular:624.59Ref: TM-T3375
2mg39,00€5mg58,00€10mg88,00€25mg168,00€50mg255,00€100mg359,00€200mg525,00€1mL*10mM (DMSO)81,00€Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Fórmula:C36H56O8Pureza:98.55% - >99.99%Forma y color:White To Off-White SolidPeso molecular:616.83Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Fórmula:C18H18Cl3FN4OSPureza:99.96%Forma y color:SolidPeso molecular:463.8TAS-301
CAS:TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.Fórmula:C23H19NO3Pureza:99.55%Forma y color:SolidPeso molecular:357.4Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Forma y color:SolidPeso molecular:570.64Ref: TM-T3211
1mg49,00€5mg84,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€1mL*10mM (DMSO)90,00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Fórmula:C25H22N6O2Pureza:98% - 99.70%Forma y color:SolidPeso molecular:438.48Ref: TM-T6278
1mg44,00€5mg86,00€10mg135,00€25mg254,00€50mg423,00€100mg605,00€200mg845,00€1mL*10mM (DMSO)94,00€Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Fórmula:C19H20O5Pureza:97.22% - 99.91%Forma y color:SolidPeso molecular:328.36Ref: TM-T3S1416
1mg40,00€5mg84,00€10mg113,00€25mg245,00€50mg439,00€100mg627,00€500mg1.288,00€1mL*10mM (DMSO)93,00€Ζ-Stat
CAS:ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis inFórmula:C10H8O10S3Pureza:99.85%Forma y color:SolidPeso molecular:384.36Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFórmula:C21H18ClNO4Pureza:95% - 99.19%Forma y color:Yellow To Orange SolidPeso molecular:383.83Ref: TM-T3419
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg205,00€100mg289,00€200mg432,00€1mL*10mM (DMSO)65,00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Fórmula:C28H25F2N3OSPureza:97.04%Forma y color:SolidPeso molecular:489.58Ref: TM-T26019
1mg39,00€2mg52,00€5mg87,00€10mg138,00€25mg281,00€50mg425,00€100mg625,00€200mg883,00€1mL*10mM (DMSO)95,00€Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFórmula:C26H44NNaO5SPureza:99.79% - 99.93%Forma y color:SolidPeso molecular:505.69Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFórmula:C15H10O5Pureza:97.93%Forma y color:SolidPeso molecular:270.24
