HSP
Los inhibidores de proteínas de choque térmico (HSP) se dirigen a las HSP, una familia de chaperonas moleculares que asisten en el plegamiento de proteínas, la estabilidad y la protección contra daños inducidos por el estrés. Las HSP suelen estar sobreexpresadas en células cancerosas, ayudándolas a sobrevivir en condiciones estresantes como la hipoxia y la quimioterapia. Inhibir las HSP puede interrumpir estos mecanismos de protección, lo que conduce a la muerte celular. Por lo tanto, los inhibidores de HSP son valiosos en la terapia contra el cáncer y en la investigación de respuestas al estrés. En CymitQuimica, ofrecemos una amplia gama de inhibidores de HSP de alta calidad para apoyar su investigación en homeostasis de proteínas, respuestas al estrés y oncología.
Se han encontrado 169 productos de "HSP"
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GRP78-IN-3
CAS:<p>GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.</p>Fórmula:C17H18N4O2SPureza:99.11%Forma y color:SoildPeso molecular:342.42CC-99677
CAS:<p>CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.</p>Fórmula:C22H20ClN5O3SPureza:99.59%Forma y color:SolidPeso molecular:469.94Novobiocin Sodium
CAS:<p>Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.</p>Fórmula:C31H35N2NaO11Pureza:99% - 99.28%Forma y color:SolidPeso molecular:634.61IPI-493
CAS:<p>IPI-493 is a bioactive chemical.</p>Fórmula:C28H39N3O8Pureza:>99.99%Forma y color:SolidPeso molecular:545.62Ethoxyquin
CAS:<p>Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.</p>Fórmula:C14H19NOPureza:97.15% - 98.73%Forma y color:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Peso molecular:217.31Arimoclomol maleate
CAS:<p>Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.</p>Fórmula:C18H24ClN3O7Pureza:99.44% - 99.98%Forma y color:SolidPeso molecular:429.85Rifabutin
CAS:<p>Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.</p>Fórmula:C46H62N4O11Pureza:98.87% - 99.7%Forma y color:Red-Violet Crystalline PowderPeso molecular:847Col003
CAS:<p>Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).</p>Fórmula:C14H11NO4Pureza:98.67% - 99.03%Forma y color:SolidPeso molecular:257.24PU-H71 HCl
CAS:<p>PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.</p>Fórmula:C18H22ClIN6O2SPureza:98.95%Forma y color:SoildPeso molecular:548.83Gamitrinib TPP
CAS:<p>Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.</p>Fórmula:C52H65N3O8PPureza:98%Forma y color:SolidPeso molecular:891.078NMS-E973
CAS:<p>NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.</p>Fórmula:C22H22N4O7Pureza:99.84%Forma y color:SolidPeso molecular:454.43HEMTAC WEE1 degrader-1
CAS:<p>HEMTACWEE1degrader-1 is a WEE1-targeting heterobifunctional chimeric degrader (HEMTAC) facilitated by HSP90, exhibiting an HSP90 enzyme inhibitory activity with an IC50 of 16.76 nM. It enhances the ubiquitination and subsequent degradation of WEE1, effectively blocking the G2/M cell cycle transition. This compound shows anticancer properties in patient-derived xenograft (PDX) models of acute myeloid leukemia (AML). HEMTACWEE1degrader-1 is utilized in AML research.</p>Fórmula:C57H71N15O6Forma y color:SolidPeso molecular:1062.273-Phenyltoxoflavin
CAS:<p>3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.</p>Fórmula:C13H11N5O2Pureza:99.88%Forma y color:SolidPeso molecular:269.266BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Fórmula:C45H47Br2N2O3PForma y color:SolidPeso molecular:854.65Shepherdin (79-87)
CAS:<p>Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.</p>Fórmula:C41H64N12O12SPureza:98%Forma y color:SolidPeso molecular:949.09JG-258
CAS:<p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>Fórmula:C20H22ClN3OS3Forma y color:SolidPeso molecular:452.06trans-Dehydrocurvularin
CAS:<p>trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.</p>Fórmula:C16H18O5Forma y color:SolidPeso molecular:290.315HSP70/SIRT2-IN-1
<p>HSP70/SIRT2-IN-1 (Compound 2a) serves as a dual inhibitor targeting both SIRT2 and HSP70, exhibiting an IC50 of 17.3±2.0 μM against SIRT2.</p>Pureza:98%Forma y color:Odour SolidAlvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Fórmula:C34H49F3N4O10Forma y color:SolidPeso molecular:730.34008Myrtucommulone
CAS:<p>Myrtucommulone is an inhibitor of the chaperonin activity of HSP60, correlating to LRP130 and LONP aggregation.</p>Fórmula:C38H52O10Pureza:98%Forma y color:SolidPeso molecular:668.81p5 Ligand for Dnak and DnaJ
CAS:<p>P5 is a nonapeptide ligand for DnaK/DnaJ, mimicking the key sites of mitochondrial aspartate aminotransferase presequence.</p>Fórmula:C44H81N15O11SPureza:98%Forma y color:SolidPeso molecular:1028.27PROTAC HSP90 degrader BP3
CAS:<p>PROTAC BP3 selectively degrades HSP90, inhibits breast cancer growth (DC50=0.99µM), CRBN-dependent.</p>Fórmula:C32H29ClN8O5Forma y color:SolidPeso molecular:641.08MAL3-101
CAS:<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Fórmula:C54H66N4O10Forma y color:SolidPeso molecular:931.12HA15-Biotin
CAS:<p>HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.</p>Fórmula:C37H45N7O5S3Forma y color:SolidPeso molecular:763.99MPC-0767
CAS:<p>MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.</p>Fórmula:C26H36BrN7O9S2Forma y color:SolidPeso molecular:734.64Hsp70-derived octapeptide
CAS:<p>TPR proteins including CHIP, TPR1, and hSGT affect luciferase refolding by DnaJ and hsc70.</p>Fórmula:C36H58N8O16Pureza:98%Forma y color:SolidPeso molecular:858.89Arimoclomol citrate
CAS:<p>Arimoclomol citrate boosts Hsp expression, aiding protein aggregation and neuron protection.</p>Fórmula:C20H28ClN3O10Forma y color:SolidPeso molecular:505.9117-DMAP-GA
CAS:<p>17-DMAP-GA, a Geldanamycin analogue, acts as an HSP90 inhibitor, leading to cell cycle abnormalities.</p>Fórmula:C33H50N4O8Forma y color:SolidPeso molecular:630.783Chetomin
CAS:<p>Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar</p>Fórmula:C31H30N6O6S4Pureza:98%Forma y color:Off-White To Fawn SolidPeso molecular:710.87TRAP1-IN-1
CAS:<p>TRAP1-IN-1 is a selective TRAP1 inhibitor, induces degradation of TRAP1 downstream proteins, inhibits OXPHOS, and disrupts mitochondrial membrane potential.</p>Fórmula:C45H39F7N2O4P2Pureza:98%Forma y color:SolidPeso molecular:866.74Grp94 Inhibitor-3
<p>Grp94 Inhibitor-3 (Compound C6) is a selective inhibitor of glucose-regulated protein 94 (Grp94), with an affinity of 5.52 μM. It shows potential for research in primary open-angle glaucoma and metastatic cancer.</p>Fórmula:C24H20ClNO4Forma y color:SolidPeso molecular:421.87Hsp90-IN-36
<p>Hsp90-IN-36 (compound 5) is an Hsp90 inhibitor with anticancer properties and exhibits an IC50 value of 14.74 μM against MCF-7 cells.</p>Fórmula:C20H13F4N3O4Forma y color:SolidPeso molecular:435.328HS-27
CAS:<p>HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.</p>Fórmula:C52H60N6O12SPureza:97.09%Forma y color:SolidPeso molecular:993.13Hsp110-STAT3 interaction-IN-2
<p>Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).</p>Fórmula:C24H18F3N5O3Forma y color:SolidPeso molecular:481.43NPX800
CAS:<p>NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.</p>Fórmula:C32H32FN5O4Pureza:99.29%Forma y color:SolidPeso molecular:569.63HSP90-IN-35
CAS:<p>HSP90-IN-35 is an inhibitor targeting Hsp90, exhibiting anticancer activity. It demonstrates an IC50 ranging from 0.05 to 0.5 μM against Her2. Additionally, HSP90-IN-35 can be utilized in the synthesis of PROTAC.</p>Fórmula:C27H33N5O5Forma y color:SolidPeso molecular:507.58DN401
CAS:<p>DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.</p>Fórmula:C13H9BrClN5O2Pureza:99.63%Forma y color:SolidPeso molecular:382.6Zelavespib hydrochloride
<p>Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 nM in MDA-MB-468 cells.</p>Pureza:98%Forma y color:Odour SolidNDNA4
<p>NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.</p>Fórmula:C31H35F3N2O5SPureza:98%Forma y color:SolidPeso molecular:604.68TRAP1-IN-2
CAS:<p>TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients.</p>Fórmula:C46H42F6N2O5P2Pureza:98%Forma y color:SolidPeso molecular:878.77HSP90-IN-25
<p>HSP90-IN-25 (compound 4a) is an inhibitor targeting HSP90, specifically impeding its ATPase function [1].</p>Fórmula:C29H48O10Pureza:98%Forma y color:SolidPeso molecular:556.69PROTAC Hsp90α degrader 1
<p>Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.</p>Fórmula:C43H50N6O7Pureza:98%Forma y color:SolidPeso molecular:762.89NDNA3
<p>NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10A</p>Fórmula:C28H32N2O3SPureza:98%Forma y color:SolidPeso molecular:476.63HSP90-IN-23
<p>HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an IC50 of 9nM.</p>Fórmula:C22H24N2O6SPureza:98%Forma y color:SolidPeso molecular:444.5Palmitic acid-1-13C
CAS:<p>Palmitic acid-13C, a 16-C saturated fatty acid internal standard for GC/LC-MS, is prevalent in plasma lipids and influences protein acylation and COX-2 levels.</p>Fórmula:C16H32O2Forma y color:SolidPeso molecular:257.422CCT245232
CAS:<p>CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.</p>Fórmula:C27H23N3O4Forma y color:SolidPeso molecular:453.49PU-H71
CAS:<p>PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.</p>Fórmula:C18H21IN6O2SPureza:98.31% - 99.937%Forma y color:SolidPeso molecular:512.37Debio 0932
CAS:<p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>Fórmula:C22H30N6O2SPureza:98.98%Forma y color:SolidPeso molecular:442.58Dihydroberberine
CAS:<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Fórmula:C20H19NO4Pureza:93.77%Forma y color:SolidPeso molecular:337.37Pifithrin-μ
CAS:<p>Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.</p>Fórmula:C8H7NO2SPureza:99.33% - 99.79%Forma y color:SolidPeso molecular:181.21MK2-IN-1 hydrochloride
CAS:<p>MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.</p>Fórmula:C27H26Cl2N4O2Pureza:97.32%Forma y color:SolidPeso molecular:509.43XL888
CAS:<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Fórmula:C29H37N5O3Pureza:99.18%Forma y color:SolidPeso molecular:503.64HM03 trihydrochloride
CAS:<p>HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.</p>Fórmula:C26H30Cl4N4O2Forma y color:SolidPeso molecular:572.35Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Fórmula:C31H43N3O8Pureza:99.07% - 99.83%Forma y color:Dark Purple SolidPeso molecular:585.69VER49009
CAS:<p>VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).</p>Fórmula:C19H18ClN3O4Pureza:98.95% - >99.99%Forma y color:SolidPeso molecular:387.82MitoBloCK-10
CAS:<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Fórmula:C12H8FN3O3SPureza:99.51%Forma y color:SolidPeso molecular:293.27HSP70-IN-1
CAS:<p>HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).</p>Fórmula:C24H28N6O2SPureza:99.91%Forma y color:SolidPeso molecular:464.58HM03
CAS:<p>HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.</p>Fórmula:C26H27ClN4O2Pureza:97.15%Forma y color:SolidPeso molecular:462.97VER-50589
CAS:<p>VER-50589 is a potent HSP90 inhibitor.</p>Fórmula:C19H17ClN2O5Pureza:99.96% - >99.99%Forma y color:SolidPeso molecular:388.8MK2-IN-1
CAS:<p>MK2-IN-1 is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.</p>Fórmula:C27H25ClN4O2Forma y color:SolidPeso molecular:472.97MKT-077
CAS:<p>MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines.</p>Fórmula:C21H22ClN3OS2Pureza:98.2%Forma y color:SolidPeso molecular:432HSP27 inhibitor J2
CAS:<p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>Fórmula:C13H12O4SPureza:99.51%Forma y color:SolidPeso molecular:264.3ML346
CAS:<p>ML346 is a novel activator of Hsp70.</p>Fórmula:C14H12N2O4Pureza:97.32% - 99.36%Forma y color:SolidPeso molecular:272.262-hexyl-4-Pentynoic Acid
CAS:<p>2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.</p>Fórmula:C11H18O2Pureza:98%Forma y color:SolidPeso molecular:182.26Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H31N3O5Pureza:98% - 99.25%Forma y color:SolidPeso molecular:465.54Onalespib
CAS:<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Fórmula:C24H31N3O3Pureza:98.05% - 99.66%Forma y color:SolidPeso molecular:409.52Rocaglamide
CAS:<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Fórmula:C29H31NO7Pureza:95.32% - 99.67%Forma y color:SolidPeso molecular:505.56Alvespimycin hydrochloride
CAS:<p>Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.</p>Fórmula:C32H48N4O8·HClPureza:99.94%Forma y color:SolidPeso molecular:653.21PF-04929113 Mesylate
CAS:<p>PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37</p>Fórmula:C26H34F3N5O7SPureza:99% - 99.46%Forma y color:SolidPeso molecular:617.63JG-98
CAS:<p>JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 μM).</p>Fórmula:C24H21Cl2N3OS3Pureza:99.13%Forma y color:SolidPeso molecular:534.53Teprenone
CAS:<p>Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).</p>Fórmula:C23H38OPureza:99.1% - 99.96%Forma y color:SolidPeso molecular:330.55DDO-5936
CAS:<p>DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.</p>Fórmula:C25H29N5O4SPureza:99.81%Forma y color:SolidPeso molecular:495.59NVP-HSP990
CAS:<p>NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).</p>Fórmula:C20H18FN5O2Pureza:98.03% - 99.32%Forma y color:SolidPeso molecular:379.39L-Alanyl-L-glutamine
CAS:<p>L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.</p>Fórmula:C8H15N3O4Pureza:99.71% - 99.97%Forma y color:SolidPeso molecular:217.22PF04929113
CAS:<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Fórmula:C25H30F3N5O4Pureza:99.04%Forma y color:SolidPeso molecular:521.53Eupalinolide A
CAS:<p>Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.</p>Fórmula:C24H30O9Pureza:98.82% - 99.22%Forma y color:SolidPeso molecular:462.49Grp94 Inhibitor-1
CAS:<p>Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).</p>Fórmula:C22H28N2O2Pureza:97.02%Forma y color:SolidPeso molecular:352.47Paeoniflorin
CAS:<p>Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.</p>Fórmula:C23H28O11Pureza:96.9% - 97.43%Forma y color:White Fine PowderPeso molecular:480.46Gedunin
CAS:<p>Gedunin, a Meliaceae seed limonoid, inhibits Hsp90 and ovarian cancer growth.</p>Fórmula:C28H34O7Pureza:99.64% - 99.68%Forma y color:SolidPeso molecular:482.57Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Fórmula:C20H20N4O3Pureza:98% - 99.95%Forma y color:SolidPeso molecular:364.4TRC051384
CAS:<p>TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.</p>Fórmula:C25H31N5O4Pureza:98.79%Forma y color:SolidPeso molecular:465.54KRIBB11
CAS:<p>KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.</p>Fórmula:C13H12N6O2Pureza:97.25% - 99.91%Forma y color:SolidPeso molecular:284.27Pimitespib
CAS:<p>Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).</p>Fórmula:C25H26N8OPureza:99.22% - 99.49%Forma y color:SolidPeso molecular:454.53VER-49009
CAS:<p>VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).</p>Fórmula:C19H18ClN3O4Pureza:99.36% - 99.99%Forma y color:SolidPeso molecular:387.82TRC051384 HCl
CAS:<p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>Fórmula:C25H32ClN5O4Pureza:97.55%Forma y color:SolidPeso molecular:502.01BIIB021
CAS:<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Fórmula:C14H15ClN6OPureza:98% - 99.82%Forma y color:SolidPeso molecular:318.76Geldanamycin
CAS:<p>Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.</p>Fórmula:C29H40N2O9Pureza:97.59% - 99.27%Forma y color:Yellow To Orange PowderPeso molecular:560.64Feretoside
CAS:<p>Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).</p>Fórmula:C17H24O11Pureza:99.85%Forma y color:SolidPeso molecular:404.37HA15
CAS:<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58Palmitic acid
CAS:<p>Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.</p>Fórmula:C16H32O2Pureza:99.17% - 99.67%Forma y color:White Crystalline Scales SolidPeso molecular:256.42KNK437
CAS:<p>KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).</p>Fórmula:C13H11NO4Pureza:98.90%Forma y color:SolidPeso molecular:245.23DTHIB
CAS:<p>DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.</p>Fórmula:C13H9ClFN3O3Pureza:98.86% - 99.29%Forma y color:SolidPeso molecular:309.68Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Fórmula:C33H25F6N3O3Pureza:99.75%Forma y color:SolidPeso molecular:625.56Azadiradione
CAS:<p>Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica</p>Fórmula:C28H34O5Pureza:99.52%Forma y color:SolidPeso molecular:450.57HSF1A
CAS:<p>HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.</p>Fórmula:C21H19N3O2S2Pureza:98.89%Forma y color:SolidPeso molecular:409.52YUM70
CAS:<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Fórmula:C21H19ClN2O4Pureza:97.25%Forma y color:SolidPeso molecular:398.84KBU2046
CAS:<p>KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.</p>Fórmula:C15H11FO2Pureza:99.89%Forma y color:SolidPeso molecular:242.24VER-82576
CAS:<p>VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.</p>Fórmula:C21H23Cl2N5O2SPureza:97.31% - 99.85%Forma y color:SolidPeso molecular:480.41VER-155008
CAS:<p>VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.</p>Fórmula:C25H23Cl2N7O4Pureza:97.03% - 99.55%Forma y color:SolidPeso molecular:556.4PU-H54
CAS:<p>PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.</p>Fórmula:C18H19N5SPureza:99.13%Forma y color:SolidPeso molecular:337.44
