HSP
Los inhibidores de proteínas de choque térmico (HSP) se dirigen a las HSP, una familia de chaperonas moleculares que asisten en el plegamiento de proteínas, la estabilidad y la protección contra daños inducidos por el estrés. Las HSP suelen estar sobreexpresadas en células cancerosas, ayudándolas a sobrevivir en condiciones estresantes como la hipoxia y la quimioterapia. Inhibir las HSP puede interrumpir estos mecanismos de protección, lo que conduce a la muerte celular. Por lo tanto, los inhibidores de HSP son valiosos en la terapia contra el cáncer y en la investigación de respuestas al estrés. En CymitQuimica, ofrecemos una amplia gama de inhibidores de HSP de alta calidad para apoyar su investigación en homeostasis de proteínas, respuestas al estrés y oncología.
Se han encontrado 176 productos para "HSP".
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Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Fórmula:C20H19NO4Pureza:99.86%Forma y color:Yellow SolidPeso molecular:337.37TRC051384 HCl
CAS:TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.Fórmula:C25H32ClN5O4Pureza:97.55%Forma y color:Yellow SolidPeso molecular:502.01DTHIB
CAS:DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.Fórmula:C13H9ClFN3O3Pureza:98.86% - 99.29%Forma y color:SolidPeso molecular:309.68Ref: TM-T8858
1mg34,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg99,00€25mg200,00€50mg319,00€100mg512,00€500mg1.071,00€Luminespib
CAS:Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.Fórmula:C26H31N3O5Pureza:98% - 99.25%Forma y color:SolidPeso molecular:465.54Ref: TM-T1989
5mg54,00€1mL*10mM (DMSO)59,00€10mg77,00€25mg138,00€50mg210,00€100mg344,00€200mg512,00€500mg825,00€KNK437
CAS:KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).Fórmula:C13H11NO4Pureza:98.90%Forma y color:SolidPeso molecular:245.23Ref: TM-T2444
2mg38,00€5mg54,00€1mL*10mM (DMSO)59,00€10mg77,00€25mg149,00€50mg220,00€100mg331,00€200mg530,00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Fórmula:C24H31N3O3Pureza:99.01% - 99.66%Forma y color:SolidPeso molecular:409.52Gedunin
CAS:Gedunin, a Meliaceae seed limonoid, inhibits Hsp90 and ovarian cancer growth.Fórmula:C28H34O7Pureza:99.64% - 99.68%Forma y color:SolidPeso molecular:482.57Ref: TM-T21883
1mg371,00€5mg1.108,00€1mL*10mM (DMSO)1.215,00€10mg1.513,00€25mg2.242,00€50mg3.025,00€100mg4.078,00€Palmitic acid
CAS:Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Fórmula:C16H32O2Pureza:99.17% - 99.67%Forma y color:White SolidPeso molecular:256.42MK2-IN-1
CAS:MK2-IN-1 is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.Fórmula:C27H25ClN4O2Forma y color:SolidPeso molecular:472.97L-Alanyl-L-glutamine
CAS:L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.Fórmula:C8H15N3O4Pureza:99.71% - 99.97%Forma y color:White SolidPeso molecular:217.22Paeoniflorin
CAS:Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.Fórmula:C23H28O11Pureza:96.9% - 97.43%Forma y color:White Fine PowderPeso molecular:480.46Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Fórmula:C31H43N3O8Pureza:98.24% - 99.83%Forma y color:Purple SolidPeso molecular:585.69HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58KW-2478
CAS:KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.Fórmula:C30H42N2O9Pureza:98.68% - 99.52%Forma y color:SolidPeso molecular:574.66Ref: TM-T6558
1mg52,00€2mg77,00€5mg113,00€1mL*10mM (DMSO)145,00€10mg177,00€25mg299,00€50mg447,00€100mg627,00€Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Fórmula:C29H40N2O9Pureza:97.59% - 99.27%Forma y color:Yellow To Orange PowderPeso molecular:560.64Iroxanadine hydrochloride
CAS:Iroxanadine hydrochloride is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.Fórmula:C14H21ClN4OForma y color:SolidPeso molecular:296.8HSP27 inhibitor J2
CAS:HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function ofFórmula:C13H12O4SPureza:99.51%Forma y color:SolidPeso molecular:264.3Ref: TM-T7265
1mg123,00€2mg175,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg447,00€25mg713,00€50mg1.009,00€100mg1.341,00€Feretoside
CAS:Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).Fórmula:C17H24O11Pureza:99.85%Forma y color:SolidPeso molecular:404.37Ref: TM-TQ0280
1mg73,00€5mg167,00€1mL*10mM (DMSO)190,00€10mg260,00€25mg440,00€50mg628,00€100mg872,00€200mg1.153,00€DDO-5936
CAS:DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.Fórmula:C25H29N5O4SPureza:99.81%Forma y color:SolidPeso molecular:495.59Ref: TM-T9202
1mg34,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg119,00€25mg250,00€50mg369,00€100mg525,00€200mg710,00€NVP-HSP990
CAS:NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).Fórmula:C20H18FN5O2Pureza:98.03% - 99.32%Forma y color:White SolidPeso molecular:379.39
