HSP
Los inhibidores de proteínas de choque térmico (HSP) se dirigen a las HSP, una familia de chaperonas moleculares que asisten en el plegamiento de proteínas, la estabilidad y la protección contra daños inducidos por el estrés. Las HSP suelen estar sobreexpresadas en células cancerosas, ayudándolas a sobrevivir en condiciones estresantes como la hipoxia y la quimioterapia. Inhibir las HSP puede interrumpir estos mecanismos de protección, lo que conduce a la muerte celular. Por lo tanto, los inhibidores de HSP son valiosos en la terapia contra el cáncer y en la investigación de respuestas al estrés. En CymitQuimica, ofrecemos una amplia gama de inhibidores de HSP de alta calidad para apoyar su investigación en homeostasis de proteínas, respuestas al estrés y oncología.
Se han encontrado 176 productos para "HSP".
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TRC051384
CAS:TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.Fórmula:C25H31N5O4Pureza:98.79%Forma y color:SolidPeso molecular:465.54Ref: TM-T3527
1mg34,00€5mg75,00€1mL*10mM (DMSO)77,00€10mg105,00€25mg200,00€50mg281,00€100mg409,00€200mg590,00€TRC051384 HCl
CAS:TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.Fórmula:C25H32ClN5O4Pureza:97.55%Forma y color:Yellow SolidPeso molecular:502.01BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Fórmula:C14H15ClN6OPureza:98% - 99.82%Forma y color:SolidPeso molecular:318.76MKT-077
CAS:MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines.Fórmula:C21H22ClN3OS2Pureza:98.2%Forma y color:SolidPeso molecular:432Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Fórmula:C8H7NO2SPureza:99.33% - 99.79%Forma y color:SolidPeso molecular:181.21XL888
CAS:XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Fórmula:C29H37N5O3Pureza:99.18%Forma y color:SolidPeso molecular:503.64HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Fórmula:C24H28N6O2SPureza:99.91%Forma y color:SolidPeso molecular:464.58Ref: TM-T3487
1mg90,00€5mg215,00€1mL*10mM (DMSO)219,00€10mg334,00€25mg587,00€50mg802,00€100mg1.108,00€MK2-IN-1 hydrochloride
CAS:MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.Fórmula:C27H26Cl2N4O2Pureza:97.32%Forma y color:SolidPeso molecular:509.43KNK437
CAS:KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).Fórmula:C13H11NO4Pureza:98.90%Forma y color:SolidPeso molecular:245.23Ref: TM-T2444
2mg38,00€5mg54,00€1mL*10mM (DMSO)59,00€10mg77,00€25mg149,00€50mg220,00€100mg331,00€200mg530,00€Palmitic acid
CAS:Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Fórmula:C16H32O2Pureza:99.17% - 99.67%Forma y color:White SolidPeso molecular:256.42HSP27 inhibitor J2
CAS:HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function ofFórmula:C13H12O4SPureza:99.51%Forma y color:SolidPeso molecular:264.3Ref: TM-T7265
1mg123,00€2mg175,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg447,00€25mg713,00€50mg1.009,00€100mg1.341,00€VER-82576
CAS:VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.Fórmula:C21H23Cl2N5O2SPureza:97.31% - 99.85%Forma y color:SolidPeso molecular:480.41KRIBB11
CAS:KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.Fórmula:C13H12N6O2Pureza:97.25% - 99.91%Forma y color:SolidPeso molecular:284.27Ref: TM-T3652
5mg49,00€1mL*10mM (DMSO)50,00€10mg73,00€25mg150,00€50mg249,00€100mg484,00€200mg680,00€500mg1.035,00€VER-49009
CAS:VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).Fórmula:C19H18ClN3O4Pureza:99.36% - 99.99%Forma y color:SolidPeso molecular:387.82Ref: TM-T3454
2mg43,00€1mL*10mM (DMSO)50,00€5mg60,00€10mg96,00€25mg156,00€50mg245,00€100mg335,00€200mg475,00€HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Fórmula:C26H27ClN4O2Pureza:97.15%Forma y color:SolidPeso molecular:462.972-hexyl-4-Pentynoic Acid
CAS:2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Fórmula:C11H18O2Pureza:98%Forma y color:SolidPeso molecular:182.26Luminespib
CAS:Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.Fórmula:C26H31N3O5Pureza:98% - 99.25%Forma y color:SolidPeso molecular:465.54Ref: TM-T1989
5mg54,00€1mL*10mM (DMSO)59,00€10mg77,00€25mg138,00€50mg210,00€100mg344,00€200mg512,00€500mg825,00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Fórmula:C24H31N3O3Pureza:99.01% - 99.66%Forma y color:SolidPeso molecular:409.52HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Fórmula:C29H31NO7Pureza:95.32% - 99.67%Forma y color:SolidPeso molecular:505.56Ref: TM-TQ0131
500µg155,00€1mg187,00€5mg410,00€1mL*10mM (DMSO)449,00€10mg710,00€25mg1.381,00€50mg2.352,00€
