Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2242 productos de "Cromatina / Epigenética"
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N-Descyclopropanecarbaldehyde Olaparib
CAS:<p>N-Descyclopropanecarbaldehyde Olaparib is a CRBN ligand for dual EGFR/PARP PROTAC, suitable for F-18 radiolabeling and tumor imaging via PET.</p>Fórmula:C20H19FN4O2Forma y color:SolidPeso molecular:366.39KDM4C-IN-1
CAS:<p>KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.</p>Fórmula:C15H14N4O3Pureza:99.33%Forma y color:SolidPeso molecular:298.3AZ505 ditrifluoroacetate
CAS:<p>AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).</p>Fórmula:C33H40Cl2F6N4O8Forma y color:SolidPeso molecular:805.59GSK2879552
CAS:<p>GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.</p>Fórmula:C23H28N2O2Pureza:99.22%Forma y color:SolidPeso molecular:364.48GSK778
CAS:<p>GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.</p>Fórmula:C30H33N5O3Pureza:98.42%Forma y color:SolidPeso molecular:511.61SGC-iMLLT
CAS:SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular targetFórmula:C22H24N6OPureza:99.21% - 99.92%Forma y color:SolidPeso molecular:388.47TPOP146
CAS:<p>TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).</p>Fórmula:C27H35N3O5Pureza:98%Forma y color:SolidPeso molecular:481.58DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Fórmula:C26H35N7O5Forma y color:SolidPeso molecular:525.6AS-85
CAS:<p>AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.</p>Fórmula:C26H28F3N5O3S2Pureza:98.96%Forma y color:SolidPeso molecular:579.66KDM4-IN-3
CAS:<p>KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.</p>Fórmula:C17H14N4OForma y color:SolidPeso molecular:290.32(2R)-Octyl-α-hydroxyglutarate
CAS:<p>(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.</p>Fórmula:C13H24O5Forma y color:SolidPeso molecular:260.33GSK-J2
CAS:<p>GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.</p>Fórmula:C22H23N5O2Pureza:97.55%Forma y color:SolidPeso molecular:389.45PROTAC EZH2 Degrader-1
CAS:<p>PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.</p>Fórmula:C54H67N7O8Forma y color:SolidPeso molecular:942.15Itacitinib adipate
CAS:<p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>Fórmula:C32H33F4N9O5Forma y color:SolidPeso molecular:699.66Boc-Lys(Ac)-AMC
CAS:<p>Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).</p>Fórmula:C23H31N3O6Pureza:99.87%Forma y color:SolidPeso molecular:445.51CHZ868
CAS:<p>CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.</p>Fórmula:C22H19F2N5O2Pureza:99.38%Forma y color:SolidPeso molecular:423.42GSK9311
CAS:<p>GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).</p>Fórmula:C24H31N5O3Pureza:98%Forma y color:SolidPeso molecular:437.53ADTL-SA1215
CAS:<p>ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.</p>Fórmula:C26H29I2NO3Pureza:99.23%Forma y color:SolidPeso molecular:657.32Fenbendazole-d3
CAS:<p>Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.</p>Fórmula:C15H10D3N3O2SForma y color:SolidPeso molecular:302.37(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Fórmula:C39H72O5Forma y color:SolidPeso molecular:620.99
