Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2238 productos de "Cromatina / Epigenética"
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EPZ015666
CAS:<p>EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.</p>Fórmula:C20H25N5O3Pureza:98% - 99.64%Forma y color:SolidPeso molecular:383.44BI-9564
CAS:<p>BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.</p>Fórmula:C20H23N3O3Pureza:99.38%Forma y color:SolidPeso molecular:353.41GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Fórmula:C18H15N3O2Pureza:99.52%Forma y color:SolidPeso molecular:305.33KDM4D-IN-1
CAS:<p>KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).</p>Fórmula:C11H7N5OPureza:99.51% - >99.99%Forma y color:SolidPeso molecular:225.21LLY-507
CAS:<p>LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.</p>Fórmula:C36H42N6OPureza:99.58% - 99.93%Forma y color:SolidPeso molecular:574.764-amino-1,8-Naphthalimide
CAS:<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Fórmula:C12H8N2O2Pureza:95.13%Forma y color:Yellow Solid PowderPeso molecular:212.23,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Fórmula:C15H10O4Pureza:99.92%Forma y color:SolidPeso molecular:254.24Piribedil hydrochloride
CAS:<p>Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.</p>Fórmula:C16H19ClN4O2Forma y color:SolidPeso molecular:334.8ML324
CAS:<p>ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).</p>Fórmula:C21H23N3O2Pureza:98.22% - 98.57%Forma y color:SolidPeso molecular:349.43Upadacitinib
CAS:<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Fórmula:C17H19F3N6OPureza:98.96% - 99.94%Forma y color:SolidPeso molecular:380.37PFI-2 hydrochloride
CAS:<p>PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),</p>Fórmula:C23H26ClF4N3O3SPureza:99.31% - 99.91%Forma y color:SolidPeso molecular:535.98BMS-P5 free base
CAS:<p>BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.</p>Fórmula:C27H32N6O2Pureza:99.88%Forma y color:SolidPeso molecular:472.58Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:97.7% - 98.41%Forma y color:SolidPeso molecular:510.614'-Methoxychalcone
CAS:<p>4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.</p>Fórmula:C16H14O2Pureza:99.86%Forma y color:SolidPeso molecular:238.28BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Fórmula:C26H26F3N7O2Pureza:98% - 99.95%Forma y color:SolidPeso molecular:525.53HNHA
CAS:<p>HNHA is an inhibitor of HDAC.</p>Fórmula:C17H21NO2SPureza:98.04%Forma y color:SolidPeso molecular:303.42Amodiaquine hydrochloride
CAS:<p>Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.</p>Fórmula:C20H24Cl3N3OForma y color:SolidPeso molecular:428.78CPI-637
CAS:<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Fórmula:C22H22N6OPureza:99.89% - 99.95%Forma y color:SolidPeso molecular:386.45TIQ-A
CAS:<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Fórmula:C11H7NOSPureza:99.75%Forma y color:SolidPeso molecular:201.24GSK-J4 Hydrochloride
CAS:<p>GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.</p>Fórmula:C24H28ClN5O2Pureza:97.95% - 98.23%Forma y color:SolidPeso molecular:453.97
