Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2242 productos de "Cromatina / Epigenética"
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Cedazuridine
CAS:<p>Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.</p>Fórmula:C9H14F2N2O5Pureza:99.66%Forma y color:SolidPeso molecular:268.21BRD4 Inhibitor-20
CAS:<p>BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity.</p>Fórmula:C18H18N2O4SPureza:99.84%Forma y color:SolidPeso molecular:358.41TGP-377/421
CAS:<p>TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.</p>Fórmula:C20H16N6Pureza:98.48%Forma y color:SolidPeso molecular:340.38Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47CPUY074020
CAS:<p>CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.</p>Fórmula:C25H28N4O2Pureza:98.64%Forma y color:SolidPeso molecular:416.52STS-E412
CAS:<p>STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.</p>Fórmula:C15H15ClN4O2Pureza:99.01%Forma y color:SolidPeso molecular:318.76β-NF-JQ1
CAS:<p>β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins.</p>Fórmula:C45H42ClN5O6SPureza:97.58% - 99.15%Forma y color:SolidPeso molecular:816.36SK-575
CAS:<p>SK-575 is a potent PARP1-degrading agent effective against BRCA1/2 mutant cancers, even at low doses, and enhances tumor inhibition in mice.</p>Fórmula:C47H53FN8O8Pureza:99.39%Forma y color:SolidPeso molecular:876.97GSK-690
CAS:<p>GSK-690 is a potent, reversible and selective inhibitors of Lysine Specific Demethylase 1.</p>Fórmula:C24H23N3OPureza:98.65%Forma y color:SolidPeso molecular:369.46Bisaramil hydrochloride
CAS:<p>Bisaramil hydrochloride (Bisaramil) is an antiarrhythmic compound that inhibits free radical production.</p>Fórmula:C17H24Cl2N2O2Pureza:98.64% - 99.48%Forma y color:SolidPeso molecular:359.29ZEN-3862
CAS:<p>ZEN-3862, a BET inhibitor, blocks BRD4(BD1) at 0.16 μM & BRD4(BD2) at 0.13 μM; usable in PROTACs for BRD4 degradation.</p>Fórmula:C19H17FN2O3Pureza:97.1%Forma y color:SolidPeso molecular:340.35DC-BPi-03
CAS:<p>DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC 50 of 698.3 nM and a K d of 2.81 μM .</p>Fórmula:C14H14N4O2SPureza:98.96%Forma y color:SolidPeso molecular:302.35CMP-5
CAS:<p>CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.</p>Fórmula:C21H21N3Pureza:98.68%Forma y color:SolidPeso molecular:315.41JAK1-IN-8
CAS:<p>JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).</p>Fórmula:C22H23FN4O3SPureza:98.4%Forma y color:SolidPeso molecular:442.51MS0124
CAS:<p>MS0124 is a potent and selective G9A-like protein (GLP) inhibitor with IC50 values of 13±4 nM and 440±63 nM, respectively.</p>Fórmula:C20H29N5O3Pureza:98.97%Forma y color:SolidPeso molecular:387.48SRX3177
CAS:<p>SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.</p>Fórmula:C31H32N6O4SPureza:99.16%Forma y color:SolidPeso molecular:584.69DW14800
CAS:<p>DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.</p>Fórmula:C31H36N4O3Pureza:99.55% - 99.68%Forma y color:SolidPeso molecular:512.64PU139
CAS:<p>PU139 is a novel inhibitor of histone acetyltransferase (HAT).</p>Fórmula:C12H7FN2OSPureza:99.96%Forma y color:SolidPeso molecular:246.26KRH102140
CAS:<p>KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.</p>Fórmula:C25H24FNOPureza:98.31% - 99.61%Forma y color:SolidPeso molecular:373.46AGI-24512
CAS:<p>AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in</p>Fórmula:C24H24N4O2Pureza:98.55%Forma y color:SolidPeso molecular:400.47ML192
CAS:<p>ML192 (CID1434953) is a selective GPR55 ligand antagonist.</p>Fórmula:C20H22N4O2SPureza:99.17%Forma y color:SolidPeso molecular:382.48CARM1-IN-1
CAS:<p>CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.</p>Fórmula:C26H21Br2NO3Pureza:98.24%Forma y color:SolidPeso molecular:555.26TM2-115
CAS:<p>TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].</p>Fórmula:C28H38N6O2Pureza:97.67%Forma y color:SolidPeso molecular:490.64ZEN-3411
CAS:<p>ZEN-3411 is an BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.</p>Fórmula:C21H20N4O2Pureza:97.51% - 98.84%Forma y color:SolidPeso molecular:360.41NSC 694623
CAS:<p>NSC 694623: Potent HAT inhibitor, IC50=15.9 μM against PCAF, anti-cancer properties.</p>Fórmula:C16H16N2OSPureza:99.9%Forma y color:SolidPeso molecular:284.38ZEN-3219
CAS:<p>ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).</p>Fórmula:C19H18N2O3Pureza:99.06%Forma y color:SolidPeso molecular:322.36JAK-STAT-IN-1
CAS:<p>JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.</p>Fórmula:C21H21N5O2Pureza:99.59%Forma y color:SolidPeso molecular:375.42Izencitinib
CAS:<p>Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.</p>Fórmula:C22H26N8Pureza:99.82%Forma y color:SolidPeso molecular:402.50OXFBD04
CAS:<p>OXFBD04: Potent BRD4 inhibitor, IC50=166nM, acts on BET bromodomains; moderate CREBBP affinity; anti-cancer properties.</p>Fórmula:C17H16N2O3Pureza:99.56%Forma y color:SolidPeso molecular:296.32Procainamide
CAS:<p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>Fórmula:C13H21N3OPureza:99.92% - 99.92%Forma y color:SolidPeso molecular:235.33Corin
CAS:<p>Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).</p>Fórmula:C26H28N4O2Pureza:99.6%Forma y color:SolidPeso molecular:428.53EZH2-IN-13
CAS:<p>EZH2-IN-13 is a potent EZH2 inhibitor with potential anticancer activity.EZH2-IN-13 may be used to study diseases associated with EZH2 activity.</p>Fórmula:C34H45N5O3Pureza:98.3%Forma y color:SolidPeso molecular:571.75HDAC6 degrader 9c
CAS:<p>HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.</p>Fórmula:C37H45N9O10Pureza:>99.99%Forma y color:SolidPeso molecular:775.81DCPLA-ME
CAS:<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Fórmula:C21H38O2Pureza:99.80%Forma y color:SolidPeso molecular:322.53PARP10-IN-2
CAS:<p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>Fórmula:C14H10N2O2Pureza:99.27%Forma y color:SolidPeso molecular:238.24Butyrolactone 3
CAS:<p>Butyrolactone 3 (MB-3) is a Gcn5 inhibitor with weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and can be used in cancer.</p>Fórmula:C9H12O4Pureza:98.99% - 99.5%Forma y color:SolidPeso molecular:184.19OUL232
CAS:<p>OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.</p>Fórmula:C10H10N4O2SPureza:99.04%Forma y color:SolidPeso molecular:250.28LEM-14
CAS:<p>LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.</p>Fórmula:C25H26N4O4SPureza:98.3%Forma y color:SolidPeso molecular:478.56CD532
CAS:<p>CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.</p>Fórmula:C26H25F3N8OPureza:99.49%Forma y color:SolidPeso molecular:522.52AGI-43192
CAS:<p>AGI-43192: potent MAT2A inhibitor, crosses blood-brain barrier, may help study SAM in CNS and treat cancer.</p>Fórmula:C23H16ClF3N6OPureza:99.89%Forma y color:SolidPeso molecular:484.86EB-47
CAS:<p>EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).</p>Fórmula:C24H27N9O6Pureza:99.81%Forma y color:SolidPeso molecular:537.53HIF-2α-IN-9
CAS:<p>HIF-2α-IN-9 (compound 35r) serves as an HIF-2α inhibitor, effectively suppressing VEGF-A with an IC50 of 305 nM, and modulating growth-promoting genes within</p>Fórmula:C12H13F5O4S2Pureza:98%Forma y color:SolidPeso molecular:380.35HSP70/SIRT2-IN-2
CAS:<p>HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].</p>Fórmula:C17H13N3S3Pureza:98%Forma y color:SolidPeso molecular:355.5GSK2646264
CAS:<p>GSK2646264 (Compound 44) inhibits SYK (pIC50=7.1) and kinases like LCK, LRRK2; penetrates skin.</p>Fórmula:C24H26N2O2Forma y color:SolidPeso molecular:374.48CBP/p300-IN-17
CAS:<p>CBP/p300-IN-17 (compound 7) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.18 μM) and LK2 H3K27 (IC50: 0.69 μM).</p>Fórmula:C25H28N4O3Forma y color:SolidPeso molecular:432.51PARP7-IN-16
CAS:<p>PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.</p>Fórmula:C25H26FN4NaO4Pureza:98%Forma y color:SolidPeso molecular:488.49PHD-IN-1
CAS:<p>PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.</p>Fórmula:C24H23N7O2Pureza:98%Forma y color:SolidPeso molecular:441.49FHT-1204
CAS:<p>FHT-1204 is a potent inhibitor of SMARCA4/SMARCA2 ATPase (BRG1 and BRM) (IC50 ≤ 10 nM).</p>Fórmula:C24H23N5O5S2Forma y color:SolidPeso molecular:525.6HDAC-IN-38
CAS:<p>HDAC-IN-38: Potent HDAC1-3,5,6,8 inhibitor, boosts H3K14/H4K5 acetylation, elevates CBF, lessens cognitive decline & hippocampal atrophy.</p>Fórmula:C27H28ClN3O2Forma y color:SolidPeso molecular:461.98PARP-2-IN-1
CAS:<p>PARP-2-IN-1 is a potent and selective inhibitor of PARP-2(IC50 of 11.5 nM).</p>Fórmula:C21H19F4N5O3Pureza:98%Forma y color:SolidPeso molecular:465.4
