Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(421 productos)
- ADN girasa(11 productos)
- ADN-PK(51 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
Mostrar 3 subcategorías más
Se han encontrado 958 productos de "Daño al ADN / Reparación del ADN"
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AES-135
CAS:<p>AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.</p>Fórmula:C33H29F6N3O5SPureza:97.72%Forma y color:SolidPeso molecular:693.66Zidovudine
CAS:<p>Zidovudine, a synthetic dideoxynucleoside, blocks DNA replication by inhibiting DNA polymerase after activation.</p>Fórmula:C10H13N5O4Pureza:99.84% - 99.91%Forma y color:White To Off-White CrystalsPeso molecular:267.24Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Fórmula:C6H12N2O4PtPureza:98% - 99.72%Forma y color:White Crystalline PowderPeso molecular:371.25Mifobate
CAS:Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。Fórmula:C11H17ClO7P2Pureza:99.12%Forma y color:SolidPeso molecular:358.65GED-0507-34 Levo
CAS:<p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>Fórmula:C10H13NO3Pureza:98.19%Forma y color:SolidPeso molecular:195.22Moxifloxacin hydrochloride
CAS:<p>Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria and atypical pathogens.</p>Fórmula:C21H25ClFN3O4Pureza:99.91% - >99.99%Forma y color:SolidPeso molecular:437.89Dithranol
CAS:<p>Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially</p>Fórmula:C14H10O3Pureza:93.49% - 99.33%Forma y color:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingPeso molecular:226.23DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Fórmula:C25H25N3OPureza:98.95%Forma y color:SolidPeso molecular:383.49FEN1-IN-1
CAS:<p>FEN1-IN-1 (LNT-1), a FEN1 active site inhibitor, partly works by coordinating Mg2+ ions.</p>Fórmula:C15H12N2O5SPureza:99.65% - 99.80%Forma y color:SolidPeso molecular:332.33Nalidixic acid
CAS:<p>Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.</p>Fórmula:C12H12N2O3Pureza:99.9% - 99.95%Forma y color:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:232.24Ofloxacin
CAS:<p>Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic.</p>Fórmula:C18H20FN3O4Pureza:99.33% - 99.87%Forma y color:Off-White SolidPeso molecular:361.37Gatifloxacin
CAS:<p>Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.</p>Fórmula:C19H22FN3O4Pureza:99.50% - 99.85%Forma y color:White PowderPeso molecular:375.39LY518674
CAS:<p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>Fórmula:C23H27N3O4Pureza:98.87%Forma y color:SolidPeso molecular:409.48Acyclovir
CAS:<p>Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2,</p>Fórmula:C8H11N5O3Pureza:99.77% - >99.99%Forma y color:Crystals From Methanol SolidPeso molecular:225.2Hydroxychloroquine sulfate
CAS:<p>Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.</p>Fórmula:C18H26ClN3O·H2SO4Pureza:98.92% - 99.88%Forma y color:Odorless SolidPeso molecular:433.95Fleroxacin
CAS:<p>Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.</p>Fórmula:C17H18F3N3O3Pureza:99.58% - 99.79%Forma y color:White Needle-Like CrystalsPeso molecular:369.34Oxaquin TEA
<p>Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and</p>Fórmula:C37H48F2N5O11PPureza:99.79%Forma y color:SolidPeso molecular:807.77Elimusertib hydrochloride(1876467-74-1 free base)
<p>Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor</p>Fórmula:C20H22ClN7OPureza:98.8% - 99.03%Forma y color:SolidPeso molecular:411.89Ceramides Mixture
CAS:<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Fórmula:C36H71NO4Pureza:98%Forma y color:SolidPeso molecular:581.967Abexinostat
CAS:<p>Abexinostat (PCI-24781) is a pan-HDAC inhibitor, strongest on HDAC1; less so on HDACs 2, 3, 6, 10. Very select for HDAC8. In Phase 1/2 trials.</p>Fórmula:C21H23N3O5Pureza:98.19% - 98.43%Forma y color:SolidPeso molecular:397.42Cetaben
CAS:<p>Cetaben, a non-fibrotic drug, lowers cholesterol and triglycerides without PPARα activation.</p>Fórmula:C23H39NO2Pureza:99.59%Forma y color:SolidPeso molecular:361.56Sparfloxacin
CAS:<p>Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.</p>Fórmula:C19H22F2N4O3Pureza:99.67% - >99.99%Forma y color:Light Yellow PowderPeso molecular:392.40Lomefloxacin
CAS:<p>Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.</p>Fórmula:C17H19F2N3O3Pureza:98.59%Forma y color:Off-White To Yellow CrystalsPeso molecular:351.35Topixantrone 2HCl
CAS:<p>Topixantrone 2HCl is a DNA topoisomerase inhibitor with antitumor activity for the study of gastric and prostate cancer.</p>Fórmula:C21H28Cl2N6O2Pureza:99.96% - >99.99%Forma y color:SoildPeso molecular:467.39Tallimustine HCl
CAS:<p>Tallimustine HCl, an AT-specific alkylating agent, treats leukemia in immunodeficiency mouse models.</p>Fórmula:C32H39Cl3N10O4Pureza:98.52%Forma y color:SoildPeso molecular:734.081-Naphthohydroxamic acid
CAS:<p>1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1</p>Fórmula:C11H9NO2Pureza:99.19%Forma y color:SolidPeso molecular:187.19Adenine
CAS:<p>Adenine: a purine nucleobase vital for ATP, NAD, FAD production, and DNA/RNA synthesis.</p>Fórmula:C5H5N5Pureza:99.39% - 99.95%Forma y color:SolidPeso molecular:135.13Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Fórmula:C8H14N2O2Pureza:99.67% - 99.86%Forma y color:White Crystalline PowderPeso molecular:170.21Nalidixic acid sodium salt
CAS:<p>Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.</p>Fórmula:C12H11N2NaO3Pureza:99.72% - 99.95%Forma y color:White To Off-White PowderPeso molecular:254.22LTURM34
CAS:<p>LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.</p>Fórmula:C24H18N2O3SPureza:99.34%Forma y color:SolidPeso molecular:414.48Altretamine
CAS:<p>Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.</p>Fórmula:C9H18N6Pureza:99.54%Forma y color:Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)Peso molecular:210.28G150
CAS:<p>G150 suppresses DSDNA-induced interferon; IC50: 10.2 nM. It's a potent, selective H-CGAS inhibitor.</p>Fórmula:C18H16Cl2N4O2Pureza:97.75%Forma y color:SolidPeso molecular:391.255-Azacytidine
CAS:<p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>Fórmula:C8H12N4O5Pureza:99.31% - 99.79%Forma y color:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:244.2Telomerase-IN-2
CAS:<p>Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).</p>Fórmula:C34H39N3O9Pureza:99.32%Forma y color:SolidPeso molecular:633.69NSC 31150
CAS:<p>Indomethacin sodium hydrate (Indometacin sodium hydrate) is a COX1/2 inhibitor that induces migraine headaches and may be used in studies of rheumatoid joints.</p>Fórmula:C10H5Cl2NO2SPureza:98.07%Forma y color:SolidPeso molecular:274.12MSDC-0602K
CAS:<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Fórmula:C19H16KNO5SPureza:99.42%Forma y color:SolidPeso molecular:409.5Candesartan
CAS:<p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>Fórmula:C24H20N6O3Pureza:98.3% - 99.55%Forma y color:Colorless Solid CrystallinePeso molecular:440.47Ciprofloxacin
CAS:<p>Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!</p>Fórmula:C17H18FN3O3Pureza:98.77% - 99.91%Forma y color:White PowderPeso molecular:331.34STL127705
CAS:<p>STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.</p>Fórmula:C22H20FN5O4Pureza:99.53% - 99.81%Forma y color:SolidPeso molecular:437.42BRD 4354
CAS:<p>BRD 4354 is an inhibitor of HDAC5 and HDAC9. For HDAC5 and HDAC9, the IC50s values are 0.85 and 1.88 μM, respectively.</p>Fórmula:C21H23ClN4OPureza:99.86%Forma y color:SolidPeso molecular:382.89Balofloxacin
CAS:<p>Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.</p>Fórmula:C20H24FN3O4Pureza:99.62% - 99.98%Forma y color:Crystalline SolidPeso molecular:389.42Niraparib (R-enantiomer)
CAS:<p>Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).</p>Fórmula:C19H20N4OPureza:99.83%Forma y color:SolidPeso molecular:320.39Procarbazine hydrochloride
CAS:<p>Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities.</p>Fórmula:C12H19N3O·HClPureza:96.99% - ≥98%Forma y color:(Ntp 1992)Peso molecular:257.76Chlorambucil
CAS:<p>Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.</p>Fórmula:C14H19Cl2NO2Pureza:97.37% - 98.45%Forma y color:Off-White Slightly Granular Powder Melting Point 65-69°CPeso molecular:304.21Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Fórmula:C10H11ClO3Pureza:99.47% - 99.8%Forma y color:Pale Yellow SolidPeso molecular:214.65Cisplatin
CAS:<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Fórmula:Cl2H6N2PtPureza:97.13% - 99.63%Forma y color:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecular:300.04Methotrexate
CAS:<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Fórmula:C20H22N8O5Pureza:96.84% - 99.91%Forma y color:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44Ciprofloxacin monohydrochloride
CAS:<p>Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.</p>Fórmula:C17H18FN3O3·HClPureza:99.5% - >99.99%Forma y color:White Or Light Yellow Crystalline PowderPeso molecular:367.80Foscarnet sodium
CAS:<p>Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.</p>Fórmula:CNa3O5PPureza:98.52%Forma y color:White Or Almost White Crystalline PowderPeso molecular:191.95SIRT-IN-2
CAS:<p>SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).</p>Fórmula:C15H21N5O3S2Pureza:98.26%Forma y color:SolidPeso molecular:383.49
