Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(50 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
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Se han encontrado 963 productos de "Daño al ADN / Reparación del ADN"
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RG-12525
CAS:<p>RG-12525（NID 525） is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of</p>Fórmula:C25H21N5O2Pureza:95.49%Forma y color:SolidPeso molecular:423.47Ceralasertib formate
CAS:<p>Ceralasertib: an oral ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupts DNA repair, and triggers tumor cell apoptosis.</p>Fórmula:C21H26N6O4SForma y color:SolidPeso molecular:458.54GSK-7227
CAS:<p>GSK-7227 is a novel PPARδ partial agonist that upregulates target genes in muscle cells, indicating its potential role in modulating muscle metabolism and energy.</p>Fórmula:C25H22N2O6SPureza:99.17%Forma y color:SolidPeso molecular:478.52AA-CW236
CAS:<p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>Fórmula:C17H16ClF3N4O2Forma y color:SolidPeso molecular:400.78NC190 sodium
CAS:NC190 inhibits topoisomerase II, halts FM3A cell growth (IC50: 0.019 μg/ml in 48h), and suppresses DNA synthesis by 90% at 0.1 μg/ml.Fórmula:C23H22N4NaO5Pureza:98%Forma y color:SolidPeso molecular:457.442DB-959 (free base)
CAS:<p>DB-959 is a potential agonist of PPAR.</p>Fórmula:C25H27NO5Forma y color:SolidPeso molecular:421.49KDT 501 potassium
CAS:<p>KDT 501, a PPAR agonist and G protein-coupled receptor (GPR) 120 agonist, is used potentially for the treatment of type 2 diabetes.</p>Fórmula:C21H34KO5Pureza:98%Forma y color:SolidPeso molecular:405.596Mitobronitol
CAS:<p>Mitobronitol, a brominated mannitol analog, is an alkylating anticancer drug that aids in reducing allogeneic bone marrow transplant risks.</p>Fórmula:C6H12Br2O4Forma y color:SolidPeso molecular:307.97NC182
CAS:<p>NC182 is a topo II inhibitor that shows selective and potent topo II inhibition on the induction of topo II-dependent DNA fragmentation.</p>Fórmula:C24H24N4O5Pureza:98%Forma y color:SolidPeso molecular:448.47PPARδ agonist 8
CAS:<p>Pparδ agonist 8 is a potent agonist of Pparδ. Pparδ agonist 8 has potential for the study of nonalcoholic fatty liver disease (NAFLD).</p>Fórmula:C25H29NO5Forma y color:SolidPeso molecular:423.5Chloroquinoxaline sulfonamide
CAS:Chloroquinoxaline sulfonamide (Chloroquinoxaline) is an organic micropollutant with antimicrobial activity.Fórmula:C14H11ClN4O2SPureza:99.79% - 99.89%Forma y color:SolidPeso molecular:334.78Bobcat339 hydrochloride
CAS:<p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>Fórmula:C16H13Cl2N3OPureza:99.22%Forma y color:SolidPeso molecular:334.2L82
CAS:<p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>Fórmula:C11H8ClN5O4Pureza:97.45% - 98.91%Forma y color:SolidPeso molecular:309.67ACY-957
CAS:<p>ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.</p>Fórmula:C24H23N5OSPureza:99.79%Forma y color:SolidPeso molecular:429.54BRD4097
CAS:<p>BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve</p>Fórmula:C16H17N3O2Pureza:99.75%Forma y color:SolidPeso molecular:283.33BRD2492
CAS:<p>BRD2492 is an HDAC1 and HDAC2 inhibitor with antiproliferative activity, inhibits HDAC1/2 and induces apoptosis.</p>Fórmula:C20H18N4O2Pureza:99.56%Forma y color:SolidPeso molecular:346.38Dehydroepiandrosterone sulfate
CAS:<p>Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.</p>Fórmula:C19H28O5SPureza:97.18%Forma y color:SolidPeso molecular:368.49SIRT6-IN-5
CAS:<p>SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.</p>Fórmula:C19H14N2O6Pureza:98.77%Forma y color:SolidPeso molecular:366.32Pegamotecan
CAS:<p>Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell</p>Fórmula:C52H48N6O14Pureza:96.40% - 97.83%Forma y color:SolidPeso molecular:980.984Suksdorfin
CAS:<p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>Fórmula:C21H24O7Pureza:98.54%Forma y color:SolidPeso molecular:388.41
