ADN metiltransferasa
Las metiltransferasas de ADN (DNMT) son enzimas que catalizan la adición de grupos metilo a los residuos de citosina en el ADN, lo que lleva al silenciamiento génico. La metilación aberrante del ADN está asociada con diversas enfermedades, incluido el cáncer. Los inhibidores de DNMT bloquean la actividad de estas enzimas, lo que lleva a la reactivación de genes silenciados y la inducción de apoptosis en células cancerosas. Los inhibidores de DNMT se utilizan ampliamente en la investigación epigenética y la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de DNMT de alta calidad para apoyar su investigación en epigenética, metilación del ADN y biología del cáncer.
Se han encontrado 421 productos de "ADN metiltransferasa"
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Chlorogenic Acid
CAS:Fórmula:C16H18O9Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:354.31Caffeic Acid
CAS:Fórmula:C9H8O4Pureza:>98.0%(T)(HPLC)Forma y color:White to Orange to Green powder to crystalPeso molecular:180.161-Hydrazinophthalazine Hydrochloride
CAS:Fórmula:C8H8N4·HClPureza:>99.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:196.645-Azacytidine
CAS:Fórmula:C8H12N4O5Pureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:244.21N-Phthalyl-L-tryptophan
CAS:Fórmula:C19H14N2O4Pureza:>98.0%(T)(HPLC)Forma y color:Light yellow to Amber to Dark green powder to crystalinePeso molecular:334.33Genistein
CAS:Fórmula:C15H10O5Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:270.24(-)-Epigallocatechin Gallate Hydrate
CAS:Fórmula:C22H18O11·xH2OPureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:458.38 (as Anhydrous)Zebularine
CAS:Fórmula:C9H12N2O5Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:228.20Procaine Hydrochloride
CAS:Fórmula:C13H20N2O2·HClPureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:272.77Decitabine
CAS:<p>Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.</p>Fórmula:C8H12N4O4Pureza:98.06% - 99.87%Forma y color:Physical Description Fine White Crystalline Powder Used As A DrugPeso molecular:228.214-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
CAS:Fórmula:C8H12N4O4Pureza:98%Forma y color:SolidPeso molecular:228.2053Ref: IN-DA002NLT
1g99,00€5g255,00€10g563,00€25gA consultar50gA consultar5mg30,00€100gA consultar100mg31,00€250mg53,00€A-395
CAS:<p>A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.</p>Fórmula:C26H35FN4O2SPureza:98.43%Forma y color:SolidPeso molecular:486.65Dihydro-5-azacytidine FA
<p>Dihydro-5-azacytidine FA (DHAC) is a pyrimidine analog that has antitumor activity, inhibits cell growth, inhibits DNA methylation, and may be used in the study of malignant mesothelioma.</p>Fórmula:C9H16N4O7Pureza:>99.99%Forma y color:SolidPeso molecular:292.255-Azacytidine
CAS:<p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>Fórmula:C8H12N4O5Pureza:99.31% - 99.79%Forma y color:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:244.2(E)-3,4-dihydroxycinnamic acid
CAS:Fórmula:C9H8O4Pureza:98%Forma y color:SolidPeso molecular:180.1574(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate
CAS:Fórmula:C22H18O11Pureza:98%Forma y color:SolidPeso molecular:458.3717Ref: IN-DA00IK6L
1g22,00€5g24,00€10g31,00€1kg527,00€25g55,00€50g80,00€5kgA consultar100g114,00€250g177,00€500g302,00€MAK683
CAS:<p>MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).</p>Fórmula:C20H17FN6OPureza:98.25% - 99.92%Forma y color:SolidPeso molecular:376.39Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)
CAS:Fórmula:C8H9ClN4Pureza:98%Forma y color:SolidPeso molecular:196.6369(1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid
CAS:Fórmula:C16H18O9Pureza:98%Forma y color:SolidPeso molecular:354.3087Ref: IN-DA00I681
1g30,00€5g52,00€10g75,00€1kgA consultar25g153,00€100g489,00€250gA consultar500gA consultar50kg41.345,00€250mg26,00€2(1H)-Pyrimidinone, 1-β-D-ribofuranosyl-
CAS:Fórmula:C9H12N2O5Pureza:98%Forma y color:SolidPeso molecular:228.20204H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
CAS:Fórmula:C15H10O5Pureza:97%Forma y color:SolidPeso molecular:270.2369Ref: IN-DA00I8G3
1g26,00€5g24,00€10g31,00€1kg686,00€25g52,00€50g77,00€5kgA consultar100g114,00€10kgA consultar250g181,00€500g320,00€100mg26,00€BVT948
CAS:<p>BVT948 is a protein tyrosine phosphatase (PTP) inhibitor.It can also inhibit lysine methyltransferase SETD8 (KMT5A) and several cytochrome P450 (P450) isoforms.</p>Fórmula:C14H11NO3Pureza:98.87%Forma y color:SolidPeso molecular:241.24Diperodon hydrochloride
CAS:<p>Diperodon hydrochloride (Diperocaine) is a local anesthetic that can be broken down by serolytic enzymes to produce local anesthetic effects.</p>Fórmula:C22H28ClN3O4Pureza:99.91%Forma y color:SolidPeso molecular:433.934-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
CAS:Fórmula:C8H12N4O5Pureza:98%Forma y color:SolidPeso molecular:244.2047Valemetostat
CAS:<p>Valemetostat (DS-3201) is a first-in-class EZH1/2 dual inhibitor, which can be used to study T-cell lymphoma.Cost-effective and quality-assured.</p>Fórmula:C26H34ClN3O4Pureza:98.38% - 99.08%Forma y color:SolidPeso molecular:488.02DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Fórmula:C25H25N3OPureza:98.95%Forma y color:SolidPeso molecular:383.49EBI-2511
CAS:<p>EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines).</p>Fórmula:C34H48N4O4Pureza:99.74%Forma y color:SolidPeso molecular:576.77Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Fórmula:C8H14N2O2Pureza:99.67% - 99.86%Forma y color:White Crystalline PowderPeso molecular:170.21iso-Azalansta
CAS:<p>(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study of cardiovascular disease.</p>Fórmula:C22H24ClN3O2SPureza:99.53% - 99.89%Forma y color:SoildPeso molecular:429.96Tulmimetostat
CAS:<p>Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced</p>Fórmula:C28H36ClN3O5SPureza:98.04% - 99.872%Forma y color:SolidPeso molecular:562.12Amodiaquine dihydrochloride dihydrate
CAS:<p>Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory effects</p>Fórmula:C20H28Cl3N3O3Pureza:99.97%Forma y color:SolidPeso molecular:464.82WDR5-47
CAS:<p>WDR5-47 is a potent small molecule to disturb the interaction of MLL1-WDR5 with IC50 value of 0.3μM.</p>Fórmula:C19H20ClFN4O3Pureza:98.15%Forma y color:SoildPeso molecular:406.84TB22
<p>TB22 is a non-nucleoside inhibitor of DOT1LR231Q with anticancer activity. It inhibits the malignant phenotype of lung cancer cells harboring the R231Q mutation via the MAPK/ERK signaling pathway, making it useful for lung cancer research.</p>Forma y color:Odour SolidLarsucosterol Ammonium salt
CAS:<p>Larsucosterol ammonium salt is a derivative of 25HC3S. It is a DNMT inhibitor, a LXR antagonist, an endogenous epigenetic modulator of lipid metabolism.</p>Fórmula:C27H49NO5SPureza:>99.99% - >99.99%Forma y color:SoildPeso molecular:499.75PRMT5-IN-9
CAS:<p>PRMT5-IN-9 is a novel PRMT5 inhibitor for treating cancer, with an IC 50 of 0.01 μM.</p>Fórmula:C25H23F3N6OForma y color:SolidPeso molecular:480.495UNC6852
CAS:<p>UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.</p>Fórmula:C43H48N10O6SPureza:96.64%Forma y color:SolidPeso molecular:832.97EPZ-719
CAS:<p>EPZ-719: Potent SETD2 inhibitor, IC50=0.005μM, high selectivity, potential for targeted epigenetic therapy.</p>Fórmula:C22H31FN4O3SForma y color:SolidPeso molecular:450.57EZH2-IN-5
CAS:<p>EZH2-IN-5, potent EZH2 inhibitor; IC50: 1.52 nM (wild-type), 4.07 nM (Tyr641 mutant).</p>Fórmula:C26H37BrN4O2Forma y color:SolidPeso molecular:517.512ML234
<p>ML234 is a dual inhibitor targeting EZH2/LSD1, with IC50 values of 0.09 and 0.12 μM, respectively. It demonstrates strong antiproliferative effects on prostate cancer cell lines LNCAP, PC3, and 22RV1. Additionally, ML234 inhibits tumor growth in a 22RV1 xenograft mouse model, showing potential as a research agent in prostate cancer therapeutics.</p>Forma y color:Odour SolidPRMT5-IN-11
CAS:<p>PRMT5-IN-11 demonstrates potent structure-dependent inhibition against the protein methyltransferase PRMT5:MEP50 complex at submicromolar concentrations.</p>Fórmula:C13H17N5O4Forma y color:SolidPeso molecular:307.31A-893
CAS:<p>A-893 is a cell-active inhibitor of Methyltransferase SMYD2 (IC 50 = 2.8 nM) .</p>Fórmula:C29H38Cl2N4O4Forma y color:SolidPeso molecular:577.54UNC2399
CAS:<p>UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC</p>Fórmula:C67H104N10O17SForma y color:SolidPeso molecular:1353.68C 21
CAS:<p>PRMT1 inhibitor, IC50=1.8μM; 5x more selective than PRMT6; >250x over PRMT3, CARM1.</p>Fórmula:C90H161ClN36O24Pureza:98%Forma y color:SolidPeso molecular:2166.94SGC3027
<p>SGC3027 is an inhibitor of histone methyltransferase,also is a first potent, selective and cell active chemical probe for PRMT7.</p>Fórmula:C41H47ClN6O6SPureza:98%Forma y color:SolidPeso molecular:787.37Dot1L-IN-9
<p>Dot1L-IN-9 (Compound 12) is a DOT1L inhibitor with an IC50 of 125 nM. It effectively reduces H3K79 dimethylation and is utilized in leukemia research.</p>Forma y color:Odour SolidXF056-132
CAS:<p>XF056-132 is a potent WDR5 (WD40 repeat domain protein 5) PROTAC degrader [1] .</p>Fórmula:C51H57F4N9O7SForma y color:SolidPeso molecular:1016.11
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