ADN metiltransferasa
Las metiltransferasas de ADN (DNMT) son enzimas que catalizan la adición de grupos metilo a los residuos de citosina en el ADN, lo que lleva al silenciamiento génico. La metilación aberrante del ADN está asociada con diversas enfermedades, incluido el cáncer. Los inhibidores de DNMT bloquean la actividad de estas enzimas, lo que lleva a la reactivación de genes silenciados y la inducción de apoptosis en células cancerosas. Los inhibidores de DNMT se utilizan ampliamente en la investigación epigenética y la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de DNMT de alta calidad para apoyar su investigación en epigenética, metilación del ADN y biología del cáncer.
Se han encontrado 459 productos de "ADN metiltransferasa"
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Arazine
CAS:Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.Fórmula:C20H33NO3SPureza:90%Forma y color:SolidPeso molecular:367.55JNJ-7925476 free base
CAS:JNJ-7925476 is an TRI antidepressant agent.Fórmula:C20H19NPureza:98%Forma y color:SolidPeso molecular:273.37(R)-OR-S1
CAS:(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.Fórmula:C26H34BrN3O4Pureza:98%Forma y color:SolidPeso molecular:532.47Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Fórmula:C9H16N2O6Pureza:98%Forma y color:SolidPeso molecular:248.23MS453
CAS:MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Fórmula:C20H27N5O3Forma y color:SolidPeso molecular:385.46S-Aristeromycinylhomocysteine
CAS:S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.Fórmula:C15H22N6O4SForma y color:SolidPeso molecular:382.44ZLD10A
CAS:ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.Fórmula:C37H48N4O4Pureza:98%Forma y color:SolidPeso molecular:612.8DC_517
CAS:DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).Fórmula:C33H35N3O2Forma y color:SolidPeso molecular:505.65LEM-14-1189
CAS:LEM-14-1189 inhibits NSD1/2/3 (IC50: 418/111/60 μM), targets nuclear receptors, and may treat cancer and blood diseases.Fórmula:C35H34N6O5S2Pureza:98.06%Forma y color:SolidPeso molecular:682.81PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Fórmula:C24H22N4O4Forma y color:SolidPeso molecular:430.46CSV0C018875 Hydrochloride
CAS:CSV0C018875 Hydrochloride: Novel G9a inhibitor with low toxicity, effective in enzyme/cell assays, outperforms BIX-0129.Fórmula:C18H18Cl2N2OForma y color:SolidPeso molecular:349.255D 595
CAS:D595 is a phenethylamine-type calcium channel blocker. The most potent phenylethylamine with respect to negative inotropy was D595 (EC50: 794 nmol/l).Fórmula:C25H32Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:463.44EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Fórmula:C20H22ClN7OPureza:99.95%Forma y color:SolidPeso molecular:411.89ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Fórmula:C27H28FN3O2Pureza:97.84% - 98.20%Forma y color:SolidPeso molecular:445.53BAY-6035-R-isomer
CAS:BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Fórmula:C22H28N4O3Forma y color:SolidPeso molecular:396.483-Deazaneplanocin A
CAS:3-Deazaneplanocin A (DZNep) is an EZH2 and AHCY inhibitor with antipoxigenic activity that inhibits fibrosis in the liver, kidneys, peritoneum, and airways.Fórmula:C12H14N4O3Pureza:99.03% - 99.68%Forma y color:SolidPeso molecular:262.27Valemetostat tosylate
CAS:Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.Fórmula:C33H42ClN3O7SPureza:98%Forma y color:SolidPeso molecular:660.22MM-102
CAS:MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Forma y color:SolidPeso molecular:669.8Ref: TM-T6333
1mg37,00€2mg49,00€5mg100,00€10mg165,00€25mg334,00€50mg515,00€100mg737,00€1mL*10mM (DMSO)147,00€EPZ032597
CAS:EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancerFórmula:C20H23N7OPureza:99.70%Forma y color:SolidPeso molecular:377.44PRMT4-IN-1
CAS:PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].Fórmula:C23H28FN3OPureza:98%Forma y color:SolidPeso molecular:381.49
