RAAS
Los inhibidores del sistema renina-angiotensina-aldosterona (RAAS) son compuestos que se dirigen a la vía del RAAS, conocida principalmente por su papel en la regulación de la presión arterial y el equilibrio de líquidos, pero que también influye en la angiogénesis. La vía del RAAS puede contribuir al desarrollo de nuevos vasos sanguíneos en los tumores, apoyando así su crecimiento. Inhibir los componentes del RAAS puede, por lo tanto, tener efectos antiangiogénicos, lo que convierte a estos inhibidores en herramientas valiosas en el tratamiento de ciertos cánceres y trastornos vasculares. En CymitQuimica, ofrecemos una gama de inhibidores de alta calidad del RAAS para apoyar su investigación en biología cardiovascular, oncología y angiogénesis.
Se han encontrado 91 productos para "RAAS".
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Valsartan Methyl Ester
CAS:Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.Fórmula:C25H31N5O3Pureza:99.54%Forma y color:White SolidPeso molecular:449.55Ref: TM-T67848
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg82,00€25mg129,00€50mg182,00€100mg264,00€200mg386,00€Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Fórmula:C22H23ClN6OPureza:99.48% - >99.99%Forma y color:SolidPeso molecular:422.91Pomisartan 2HCl
Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.Fórmula:C31H32Cl2N4O2Pureza:99.88%Forma y color:SoildPeso molecular:563.52Losartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFórmula:C22H22ClKN6OPureza:99.9% - >99.99%Forma y color:White To Off-White Crystalline PowderPeso molecular:461.01Olmesartan Medoxomil
CAS:Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.Fórmula:C29H30N6O6Pureza:99.89% - 99.9%Forma y color:SolidPeso molecular:558.59Ref: TM-T1518
5mg34,00€10mg50,00€1mL*10mM (DMSO)55,00€25mg57,00€50mg63,00€100mg93,00€200mg137,00€500mg260,00€Zansecimab
CAS:Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.Pureza:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.23 kDaA 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Fórmula:C39H60N12O11Pureza:98%Forma y color:SolidPeso molecular:872.97Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Fórmula:C42H64N12O11Forma y color:SolidPeso molecular:913.03Eprosartan
CAS:Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.Fórmula:C23H24N2O4SPureza:99.99%Forma y color:SolidPeso molecular:424.51PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.Forma y color:Odour SolidTetrahydro Aldosterone
CAS:Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.Fórmula:C21H32O5Forma y color:SolidPeso molecular:364.48Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Fórmula:C90H120N22O16SForma y color:SolidPeso molecular:1798.15Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Fórmula:C42H55F3N8O10Pureza:98%Forma y color:SolidPeso molecular:888.93[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Fórmula:C46H73N13O10Pureza:98%Forma y color:SolidPeso molecular:968.15TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Fórmula:C44H61N9O11Pureza:99.94%Forma y color:SolidPeso molecular:892.01Ref: TM-T40220L
1mg109,00€2mg154,00€5mg235,00€10mg349,00€1mL*10mM (DMSO)389,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Fórmula:C48H77N13O12Pureza:99.36%Forma y color:SolidPeso molecular:1028.2Ref: TM-T7575L1
2mg34,00€5mg46,00€10mg60,00€1mL*10mM (DMSO)90,00€25mg119,00€50mg192,00€100mg289,00€200mg415,00€Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Fórmula:C54H101N15O12SPureza:98%Forma y color:SolidPeso molecular:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Fórmula:C30H23N4O8·KPureza:99.99%Forma y color:SolidPeso molecular:606.62Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFórmula:C26H36N6O5Pureza:98%Forma y color:SolidPeso molecular:512.6CGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Fórmula:C54H73N13O13Pureza:99.06% - 99.92%Forma y color:SolidPeso molecular:1112.24Ref: TM-T14939L
1mg93,00€5mg279,00€10mg403,00€1mL*10mM (DMSO)622,00€25mg623,00€50mg837,00€100mg1.108,00€200mg1.504,00€Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Fórmula:C24H37N7O8Pureza:98%Forma y color:SolidPeso molecular:551.59Saralasin
CAS:Competitive non-selective angiotensin II antagonist.Fórmula:C42H65N13O10Pureza:98%Forma y color:SolidPeso molecular:912C-Type Natriuretic Peptide (1-53), human
CAS:CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.Fórmula:C251H417N81O71S3Pureza:98%Forma y color:SolidPeso molecular:5801.77TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Fórmula:C52H74N14O13Forma y color:SolidPeso molecular:1103.249Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Fórmula:C26H38F3N7O10Pureza:98%Forma y color:SolidPeso molecular:665.62Alunacedase alfa
CAS:Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.Pureza:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Forma y color:LiquidPeso molecular:85.03 kDaNesvacumab
CAS:Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.Pureza:98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.84 kDaAngiotensin II 5-valine
CAS:ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.Fórmula:C49H69N13O12Pureza:98%Forma y color:SolidPeso molecular:N/AAngiotensin amide
CAS:Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.Fórmula:C49H70N14O11Pureza:98%Forma y color:SolidPeso molecular:1031.17Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Fórmula:C129H179N37O24SForma y color:SolidPeso molecular:2662.36444Aliskiren-D6 hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Fórmula:C30H54ClN3O6Pureza:98%Forma y color:SolidPeso molecular:594.26Brain Natriuretic Peptide (1-32), rat
CAS:Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.Fórmula:C146H239N47O44S3Pureza:98%Forma y color:SolidPeso molecular:3452.94TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Fórmula:C34H54N12O7Peso molecular:742.883[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Fórmula:C48H74F3N13O12Pureza:98%Forma y color:SolidPeso molecular:1082.18Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Fórmula:C296H414N86O146P20S19Na20Forma y color:SolidPeso molecular:9201.6Spirapril hydrochloride
CAS:Spirapril hydrochloride (SCH 33844 hydrochloride) is a potent angiotensin converting enzyme inhibitor with antihypertensive activity that competitively blocks the conversion of angiotensin I to angiotensin II, functions as an orally active proagent of spiraprilat, and is extensively utilized in cardiovascular research focused on hypertension and congestive heart failure pathophysiology and therapeutic intervention.Fórmula:C22H31ClN2O5S2Pureza:99.78%Peso molecular:503.07Chlorothiazide (Standard)
CAS:Chlorothiazide (Standard) is the standard substance of Chlorothiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Fórmula:C7H6ClN3O4S2Peso molecular:295.72Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Fórmula:C22H21ClN6O2Pureza:98%Forma y color:SolidPeso molecular:440.919Angiotensin II (3-8), human
CAS:Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.Forma y color:Transparent SolidValsartan-D9
CAS:Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.Fórmula:C24H29N5O3Pureza:98%Forma y color:SolidPeso molecular:444.574PD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Fórmula:C35H34F6N4O7Pureza:98%Forma y color:White SolidPeso molecular:736.66Angiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Fórmula:C78H125N25O23Forma y color:SolidPeso molecular:1780.98Olmesartan-D4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Fórmula:C24H26N6O3Pureza:98%Forma y color:SolidPeso molecular:450.526Azilsartan-D5
CAS:Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.Fórmula:C25H20N4O5Pureza:98%Forma y color:SolidPeso molecular:461.48Olmesartan
CAS:Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.Fórmula:C24H26N6O3Pureza:91.89% - 99.81%Forma y color:White To Beige Solid SolidPeso molecular:446.50Aviptadil Acetate
CAS:Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs.Fórmula:C147H238N44O42S·C2H4O2Pureza:>99.99%Forma y color:SolidPeso molecular:3385.9Angiotensin III, human, mouse
CAS:Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).Fórmula:C46H66N12O9Pureza:98.44%Forma y color:SolidPeso molecular:931.09ANGIOTENSIN IV TFA(12676-15-2(free base))
ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.Fórmula:C42H55F3N8O10Pureza:99.12%Forma y color:SolidPeso molecular:888.92Ref: TM-T7743
2mg40,00€5mg52,00€10mg92,00€1mL*10mM (DMSO)100,00€25mg159,00€50mg230,00€100mg341,00€200mg485,00€Acein acetate
ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.Fórmula:C45H72N10O15Pureza:99.43%Forma y color:SolidPeso molecular:993.11(Sar¹)-Angiotensin II acetate
(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor.Fórmula:C51H75N13O12Pureza:99.89%Forma y color:SoildPeso molecular:1062.22Ref: TM-T35834L
1mg55,00€5mg110,00€10mg167,00€1mL*10mM (DMSO)193,00€25mg258,00€50mg366,00€100mg492,00€
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