RAAS
Los inhibidores del sistema renina-angiotensina-aldosterona (RAAS) son compuestos que se dirigen a la vía del RAAS, conocida principalmente por su papel en la regulación de la presión arterial y el equilibrio de líquidos, pero que también influye en la angiogénesis. La vía del RAAS puede contribuir al desarrollo de nuevos vasos sanguíneos en los tumores, apoyando así su crecimiento. Inhibir los componentes del RAAS puede, por lo tanto, tener efectos antiangiogénicos, lo que convierte a estos inhibidores en herramientas valiosas en el tratamiento de ciertos cánceres y trastornos vasculares. En CymitQuimica, ofrecemos una gama de inhibidores de alta calidad del RAAS para apoyar su investigación en biología cardiovascular, oncología y angiogénesis.
Se han encontrado 87 productos de "RAAS"
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Losartan potassium
CAS:<p>Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the</p>Fórmula:C22H22ClKN6OPureza:99.9% - >99.99%Forma y color:White To Off-White Crystalline PowderPeso molecular:461.01Telmisartan
CAS:<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Fórmula:C33H30N4O2Pureza:99.88% - 99.97%Forma y color:White Or Off White Crystalline PowderPeso molecular:514.62Zansecimab
CAS:<p>Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.</p>Pureza:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Forma y color:LiquidPomisartan 2HCl
<p>Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.</p>Fórmula:C31H32Cl2N4O2Pureza:99.88%Forma y color:SoildPeso molecular:563.52Olmesartan Medoxomil
CAS:<p>Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.</p>Fórmula:C29H30N6O6Pureza:99.89% - 99.9%Forma y color:White To Off-White Crystalline PowderPeso molecular:558.59Losartan
CAS:<p>Losartan (DuP-753) is an angiotensin II receptor antagonist.</p>Fórmula:C22H23ClN6OPureza:99.48% - >99.99%Forma y color:Off White Solid PowderPeso molecular:422.91Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Fórmula:C90H120N22O16SPeso molecular:1798.15Angiotensin II (3-8), human TFA
<p>Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.</p>Fórmula:C42H55F3N8O10Pureza:98%Forma y color:SolidPeso molecular:888.93Tetrahydro Aldosterone
CAS:<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Fórmula:C21H32O5Forma y color:SolidPeso molecular:364.48TRV055 acetate
<p>TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.</p>Fórmula:C44H61N9O11Pureza:99.84%Forma y color:SolidPeso molecular:892.01PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Forma y color:Odour SolidAlunacedase alfa
CAS:<p>Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.</p>Pureza:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Forma y color:LiquidEprosartan
CAS:<p>Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.</p>Fórmula:C23H24N2O4SPureza:>99.99%Forma y color:SolidPeso molecular:424.51Aclerastide
CAS:<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Fórmula:C42H64N12O11Forma y color:SolidPeso molecular:913.03[Sar1, Ile8]-Angiotensin II
CAS:<p>[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.</p>Fórmula:C46H73N13O10Pureza:98%Forma y color:SolidPeso molecular:968.15TRV056
CAS:<p>TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.</p>Fórmula:C52H74N14O13Forma y color:SolidPeso molecular:1103.249C-Type Natriuretic Peptide (1-53), human
CAS:<p>CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.</p>Fórmula:C251H417N81O71S3Pureza:98%Forma y color:SolidPeso molecular:5801.77[Sar1, Ile8]-Angiotensin II acetate
<p>'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.</p>Fórmula:C48H77N13O12Pureza:99.36%Forma y color:SolidPeso molecular:1028.2Handle region peptide, rat
CAS:<p>Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.</p>Fórmula:C54H101N15O12SPureza:98%Forma y color:SolidPeso molecular:1184.54Azilsartan Medoxomil Potassium
CAS:<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Fórmula:C30H23N4O8·KPureza:98.72%Forma y color:SolidPeso molecular:606.62[Sar1, Ile8]-Angiotensin II TFA
<p>[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.</p>Fórmula:C48H74F3N13O12Pureza:98%Forma y color:SolidPeso molecular:1082.18CGP-42112 acetate
<p>CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.</p>Fórmula:C54H73N13O13Pureza:99.06% - 99.92%Forma y color:SoildPeso molecular:1112.24Saralasin
CAS:Competitive non-selective angiotensin II antagonist.Fórmula:C42H65N13O10Pureza:98%Forma y color:PowderPeso molecular:912Angiotensin II (1-4), human
CAS:<p>Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.</p>Fórmula:C24H37N7O8Pureza:98%Forma y color:SolidPeso molecular:551.59Angiotensin II (1-4), human TFA
<p>Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.</p>Fórmula:C26H38F3N7O10Pureza:98%Forma y color:SolidPeso molecular:665.62Angiotensin II (5-8), human
CAS:<p>Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II</p>Fórmula:C26H36N6O5Pureza:98%Forma y color:SolidPeso molecular:512.6Valsartan Methyl Ester
CAS:<p>Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.</p>Fórmula:C25H31N5O3Pureza:99.54%Forma y color:SolidPeso molecular:449.55Aliskiren D6 Hydrochloride
CAS:<p>Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).</p>Fórmula:C30H54ClN3O6Pureza:98%Forma y color:SolidPeso molecular:594.26Brain Natriuretic Peptide (1-32), rat
CAS:<p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>Fórmula:C146H239N47O44S3Pureza:98%Forma y color:SolidPeso molecular:3452.94Angiotensin II 5-valine
CAS:<p>ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.</p>Fórmula:C49H69N13O12Pureza:98%Forma y color:SolidPeso molecular:N/AAngiotensin amide
CAS:<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Fórmula:C49H70N14O11Pureza:98%Forma y color:SolidPeso molecular:1031.17Nesvacumab
CAS:<p>Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.</p>Pureza:98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Forma y color:LiquidA 779
CAS:<p>A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.</p>Fórmula:C39H60N12O11Pureza:98%Forma y color:SolidPeso molecular:872.97BIBS 39
CAS:<p>BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.</p>Fórmula:C32H36N4O3Pureza:99.28%Forma y color:SolidPeso molecular:524.65Valsartan-d9
CAS:<p>Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.</p>Fórmula:C24H29N5O3Pureza:98%Forma y color:SolidPeso molecular:444.57Losartan (D4 Carboxylic Acid)
CAS:<p>Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.</p>Fórmula:C22H21ClN6O2Pureza:98%Forma y color:SolidPeso molecular:440.92Azilsartan-d5
CAS:<p>Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.</p>Fórmula:C25H20N4O5Pureza:98%Forma y color:SolidPeso molecular:461.48PD 123319 ditrifluoroacetate
CAS:<p>PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.</p>Fórmula:C35H34F6N4O7Pureza:98%Forma y color:SolidPeso molecular:736.66Olmesartan-d4
CAS:<p>Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.</p>Fórmula:C24H26N6O3Pureza:98%Forma y color:SolidPeso molecular:450.53Candesartan-d4
CAS:<p>Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.</p>Fórmula:C24H20N6O3Pureza:98%Forma y color:SolidPeso molecular:444.48Angiotensin II (3-8), human
CAS:<p>Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.</p>Forma y color:SolidOlodanrigan
CAS:<p>Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.</p>Fórmula:C32H29NO5Pureza:98.33%Forma y color:SolidPeso molecular:507.58Angiotensin I/II (1-6)
CAS:<p>Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.</p>Fórmula:C36H55N11O10Pureza:99.44%Forma y color:SolidPeso molecular:801.89Olmesartan
CAS:<p>Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.</p>Fórmula:C24H26N6O3Pureza:91.89% - 99.81%Forma y color:White To Beige Solid SolidPeso molecular:446.5BTB06584
CAS:<p>BTB06584: IF1-dependent F1 Fo-ATPase inhibitor; novel AHAS inhibitor targeting MTB.</p>Fórmula:C19H12ClNO6SPureza:97.63% - ≥95%Forma y color:SolidPeso molecular:417.82Angiotensin II 5-valine TFA
<p>Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.</p>Fórmula:C51H70F3N13O14Pureza:99.69%Forma y color:SolidPeso molecular:1146.18PD 123319
CAS:<p>PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.</p>Fórmula:C31H32N4O3Pureza:98.61% - 99.65%Forma y color:SolidPeso molecular:508.61Trans-Tranilast
CAS:<p>Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It has been used for the treatment of allergic disorders such as atopic dermatitis.</p>Fórmula:C18H17NO5Pureza:99.41% - ≥95%Forma y color:SolidPeso molecular:327.33Eprosartan Mesylate
CAS:<p>Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.</p>Fórmula:C23H24N2O4S·CH4O3SPureza:99.72% - 99.93%Forma y color:A White To Off- White PowderPeso molecular:520.62VTP-27999 TFA
CAS:<p>VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).</p>Fórmula:C28H42ClF3N4O7Pureza:98.84%Forma y color:SolidPeso molecular:639.1
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