Enzima
Los inhibidores enzimáticos son moléculas que se unen a las enzimas y disminuyen su actividad. Estos inhibidores se utilizan ampliamente en la investigación para estudiar la cinética enzimática, la regulación y el papel de enzimas específicas en las vías metabólicas. Los inhibidores enzimáticos también son cruciales en el desarrollo de fármacos, ya que muchos agentes terapéuticos funcionan inhibiendo enzimas involucradas en procesos patológicos. Al dirigirse a las enzimas, estos inhibidores pueden modular las vías bioquímicas y ofrecer tratamientos potenciales para diversas enfermedades. En CymitQuimica, ofrecemos una amplia selección de inhibidores enzimáticos de alta calidad para apoyar su investigación en bioquímica, farmacología y descubrimiento de fármacos.
Subcategorías de "Enzima"
- Anhídrido carbónico(197 productos)
- Hidroxilasa(36 productos)
- MPO(2 productos)
- Reductasa(51 productos)
- Tirosinasa(71 productos)
Se han encontrado 3621 productos de "Enzima"
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Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Fórmula:C12H21NO8SPureza:99.79% - 99.92%Forma y color:White To Off-White Crystalline PowderPeso molecular:339.36Acipimox
CAS:Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.Fórmula:C6H6N2O3Pureza:98.98%Forma y color:Low Yellow Liquid Or CrystallinePeso molecular:154.12Telotristat ethyl
CAS:Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Fórmula:C27H26ClF3N6O3Pureza:98% - 99.89%Forma y color:White SolidPeso molecular:574.98Zonisamide
CAS:Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Fórmula:C8H8N2O3SPureza:99.05% - 99.9%Forma y color:Off-White PowderPeso molecular:212.23p-Ethynylphenylalanine hydrochloride
CAS:p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Fórmula:C11H12ClNO2Pureza:99.03%Forma y color:SolidPeso molecular:225.67Tioxolone
CAS:Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Fórmula:C7H4O3SPureza:97.79%Forma y color:Light Yellow To Beige PowderPeso molecular:168.17KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Fórmula:C29H31N5O5SPureza:99.28%Forma y color:SolidPeso molecular:561.65Brinzolamide
CAS:Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Fórmula:C12H21N3O5S3Pureza:99.84% - >99.99%Forma y color:Crystalline SolidPeso molecular:383.51pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Fórmula:C6H6NO6PPureza:99.82%Forma y color:SolidPeso molecular:219.09Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Fórmula:C11H15NO5Pureza:99.96%Forma y color:Crystals From Benzene SolidPeso molecular:241.24Methazolamide
CAS:Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Fórmula:C5H8N4O3S2Pureza:99.31% - 99.77%Forma y color:Crystals From Water SolidPeso molecular:236.275-Feruloylquinic acid
CAS:5-Feruloylquinic acid, a potent Sirt1 activator, may aid in developing anti-aging drugs.Fórmula:C17H20O9Pureza:99.03%Forma y color:SolidPeso molecular:368.34Flanvotumab
CAS:Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Pureza:> 95%Forma y color:LiquidPeso molecular:145.42 kDaHydrochlorothiazide
CAS:Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。Fórmula:C7H8ClN3O4S2Pureza:99.43% - 99.50%Forma y color:Crystals Physical Description Crystals Or White Powder (Ntp 1992)Peso molecular:297.74ACT-678689
CAS:ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].Fórmula:C23H22ClFN6O4S2Pureza:99.46%Forma y color:SolidPeso molecular:565.04Ref: TM-T14119
1mg107,00€5mg245,00€1mL*10mM (DMSO)308,00€10mg371,00€25mg620,00€50mg858,00€100mg1.153,00€200mg1.549,00€Fenclonine
CAS:Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Fórmula:C9H10ClNO2Pureza:98.81% - >99.99%Forma y color:Crystals From Methanol White SolidPeso molecular:199.63Actarit
CAS:Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.Fórmula:C10H11NO3Pureza:99.64% - 99.74%Forma y color:White Or Off-White Crystal Or Crystalline SolidPeso molecular:193.2Arbutin
CAS:Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.Fórmula:C12H16O7Pureza:99.58% - 99.93%Forma y color:Colorless Elongated Prisms From Moist Ethyl Acetate White PowderPeso molecular:272.25Benzthiazide
CAS:Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.
Fórmula:C15H14ClN3O4S3Pureza:99.34% - 99.79%Forma y color:Crystals From Acetone SolidPeso molecular:431.942-Methoxy-4-propylphenol
CAS:2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.
Fórmula:C10H14O2Forma y color:SolidPeso molecular:166.22hCAXII-IN-7
hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.Fórmula:C26H25N5O6S2Pureza:98%Forma y color:SolidPeso molecular:567.64hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Fórmula:C16H14F3N3O4SForma y color:SolidPeso molecular:401.36hCAIX/XII-IN-7
Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM forFórmula:C17H14N6O3SPureza:98%Forma y color:SolidPeso molecular:382.4Tyrosinase-IN-19
Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals andPureza:98%Forma y color:Odour SolidL-Lactate Dehydrogenase from bovine heart, powder, approx. 300 U/mg
CAS:Forma y color:Lyophilised powderhCA/VEGFR-2-IN-1
hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (Fórmula:C21H17FN6O3SPureza:98%Forma y color:SolidPeso molecular:452.46Tyrosinase-IN-13
Tyrosinase-IN-13 (compound 3c), stemming from Flurbiprofen, acts as a potent non-competitive inhibitor of tyrosinase, exhibiting IC50 and Ki values of 68 μM andFórmula:C23H18ClFN4OSPureza:98%Forma y color:SolidPeso molecular:452.93Tyrosinase
CAS:Tyrosinase (Polyphenol oxidase) is a key rate-limiting enzyme encoded by the TYR gene that controls melanin production and catalyzes tyrosine oxidation.
Forma y color:SolidhCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFórmula:C23H26N6O5SPureza:98%Forma y color:SolidPeso molecular:498.55(E)-Dehydrodiconiferyl alcohol
CAS:(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.Fórmula:C20H22O6Forma y color:SolidPeso molecular:358.39Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Forma y color:LiquidPeso molecular:145.55 kDaCA inhibitor 2
Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].Fórmula:C7H9N7O3S3Pureza:98%Forma y color:SolidPeso molecular:335.39mTRP-2 (180-188)
CAS:This peptide is a TRP-tyrosinase-related protein. Its immunization results in effective induction of antitumor immunity.Fórmula:C61H78N10O14Pureza:98%Forma y color:SolidPeso molecular:1175.33Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Fórmula:C19H14BrClN4OForma y color:SolidPeso molecular:429.7CAIX-IN-4
CAIX-IN-4 (Compound 8b) is a selective inhibitor of carbonic anhydrase IX (CAIX) with an IC50 value of 0.32 μM. It holds potential for research in cancer, such as renal cell carcinoma.Forma y color:Odour SolidGZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Fórmula:C88H126F3N6NaO24S4Peso molecular:1858.755612,3-Dihydroisoginkgetin
CAS:2,3-Dihydroisoginkgetin is a Tyrosinase inhibitor with 36.84% inhibition at 0.1 mM.Fórmula:C32H24O10Pureza:98%Forma y color:SolidPeso molecular:568.53Invertase, from Saccharomyces cerevisiae
CAS:Forma y color:White to faint-yellow or light-brown powderhTYR/AbTYR-IN-1
CAS:hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.Fórmula:C18H20N2O3Pureza:99.73%Forma y color:SoildPeso molecular:312.36hCAIX/VII-IN-1
hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.Fórmula:C16H13BFN3O3Pureza:98%Forma y color:SolidPeso molecular:325.1hCA XII-IN-6
Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferativeFórmula:C11H9N5O3S2Pureza:98%Forma y color:SolidPeso molecular:323.35Carbonic anhydrase inhibitor 15
Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].Fórmula:C27H33N5O2S2Pureza:98%Forma y color:SolidPeso molecular:523.71α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Fórmula:C25H22N6OS2Forma y color:SolidPeso molecular:486.61ATP2A2 Protein, Human, Recombinant (C-His)
ATP2A2 Protein, Human, Recombinant (C-His) is expressed in E.Pureza:95%Forma y color:SoildPeso molecular:55.2 kDa (Predicted)Ref: TM-TMPH-03766
5µg89,00€10µg129,00€20µg205,00€50µg307,00€100µg419,00€200µg636,00€500µg1.132,00€1mg1.718,00€KRAS Protein, Human, Recombinant (G12C, His)
KRAS Protein, Human, Recombinant (G12C, His) is expressed in E.Pureza:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Forma y color:Lyophilized PowderPeso molecular:26 KDa (reducing condition)Ref: TM-TMPJ-00510
5µg44,00€10µg59,00€20µg95,00€50µg166,00€100µg259,00€200µg409,00€500µg800,00€1mg1.205,00€Carbonic anhydrase
CAS:Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.Forma y color:SolidCAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Fórmula:C16H13FNO4PForma y color:SolidPeso molecular:333.05662Carbonic anhydrase inhibitor 21
Compound 5h, known as Carbonic anhydrase inhibitor 21, is a specific inhibitor of carbonic anhydrase (hCA IX) with a K\(_i\) of 15.1 nM, demonstrating high selectivity compared to other isoforms studied. This compound is utilized in anticancer research.Fórmula:C32H48N4O10P2S2Peso molecular:774.22871hCAIX/XII-IN-10
hCAIX/XII-IN-10 (compound DK-8) is an inhibitor of Carbonic Anhydrase, showing potent inhibitory activity against the tumor-associated membrane-bound isoforms hCA IX and XII, with Ki values of 32.5 nM and 29.2 nM, respectively.Fórmula:C17H13N3O5SPeso molecular:371.05759Tyrosinase-IN-21
Tyrosinase-IN-21 (compound 3g) is a tyrosinase inhibitor with an IC50 value of 80.93 μM.Fórmula:C23H20N4O3S2Peso molecular:464.09768Chlorthalidone Impurity G
CAS:Chlorthalidone impurity G, a thiazide-like diuretic's contaminant, has mild antihypertensive properties and inhibits several carbonic anhydrase isoforms.Fórmula:C14H9Cl2NO2Forma y color:SolidPeso molecular:294.13Carbonic anhydrase inhibitor 24
Carbonic anhydrase inhibitor24 (Compound 11) is an inhibitor of human carbonic anhydrase. It exhibits Ki values of 10.7 nM and 7.5 nM against hCAs IX and XII, respectively.Fórmula:C16H14Cl2N2O6SPeso molecular:431.99496Pseudostellarin G
CAS:Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Fórmula:C42H56N8O9Forma y color:SolidPeso molecular:816.94hCAXII-IN-9
hCAXII-IN-9 (Compound 3I) is a selective hCAXII inhibitor with Ki values of 28 nM for hCAXII, 7192.6 nM for hCAI, 188.6 nM for hCAII, and greater than 100000 nM for hCAIX. This compound may be utilized in anti-tumor research.Fórmula:C24H30N3O7PSPeso molecular:535.15421CAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Fórmula:C23H21N5O3SForma y color:SolidPeso molecular:447.51Carbonic anhydrase inhibitor 26
Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.Fórmula:C17H14N6O4Forma y color:SolidPeso molecular:366.33AV22-149
AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .Fórmula:C23H28F3N3O6S2Forma y color:SolidPeso molecular:563.61Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Fórmula:C15H19NO3Forma y color:SolidPeso molecular:261.32β-Glucosidase, from almonds
CAS:Pureza:approx. 90% (biuret)Forma y color:White to pale yellow or beige powderPeso molecular:-hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Fórmula:C13H10FN3O4Peso molecular:291.06553Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Fórmula:C26H28N4O6S2Peso molecular:556.14503Swertiajaponin
CAS:Swertiajaponin possesses antimicrobial activity.Fórmula:C22H22O11Pureza:99.85%Forma y color:SolidPeso molecular:462.4DOTA-XYIMSR-01
CAS:DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Fórmula:C61H88N16O22S2Forma y color:SolidPeso molecular:1461.57Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Fórmula:C23H22FN3O5SForma y color:SolidPeso molecular:471.12642hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Fórmula:C22H23FN6O5SPureza:98%Forma y color:SolidPeso molecular:502.52α-Pyrone
CAS:Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9Fórmula:C5H4O2Forma y color:SolidPeso molecular:96.08Tyrosinase-IN-40
Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.Fórmula:C34H29N9O10Forma y color:SolidPeso molecular:723.648SH7s
SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.Fórmula:C24H19ClF3N5O4SForma y color:SolidPeso molecular:565.95Thrombopoietin Protein, Mouse, Recombinant
Expression system: E. coli
Length: 22-195, Partial
Activity: Cell ActivityForma y color:Lyophilized PowderPeso molecular:18.7 kDa (Predicted)TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Fórmula:C35H51N3O3Forma y color:SolidPeso molecular:561.798hCAI/II/IV-IN-28
CAS:hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.Fórmula:C14H15N3O3SPureza:98.25%Forma y color:SolidPeso molecular:305.35Tyrosinase-IN-14
Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicityFórmula:C21H13Br2N3O3SPureza:98%Forma y color:SolidPeso molecular:547.22Tyrosinase-IN-15
Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].Pureza:98%Forma y color:Odour SolidDorzolamide
CAS:Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
Fórmula:C10H16N2O4S3Pureza:98%Forma y color:White Or Almost White Crystalline PowderPeso molecular:324.44hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Fórmula:C23H22N4O7S2Forma y color:SolidPeso molecular:530.573Butobendine
CAS:Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Fórmula:C32H48N2O10Forma y color:SolidPeso molecular:620.73Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Fórmula:C17H16N6O3SForma y color:SolidPeso molecular:384.41Potassium iodide
CAS:Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。Fórmula:IKForma y color:White Solid CrystallinePeso molecular:166.01Carbonic anhydrase inhibitor 31
Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.Fórmula:C24H20N6O5SForma y color:SolidPeso molecular:504.12159hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Fórmula:C19H18N2O3SForma y color:SolidPeso molecular:354.42VM4-037
CAS:VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Fórmula:C26H29FN6O7S2Forma y color:SolidPeso molecular:620.67CAIX Inhibitor S4
CAS:CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.Fórmula:C15H17N3O4SPureza:99.07%Forma y color:SolidPeso molecular:335.38Ref: TM-T36758
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg90,00€25mg178,00€50mg334,00€100mg500,00€500mg1.099,00€hCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Fórmula:C24H28N6O6SPureza:98%Forma y color:SolidPeso molecular:528.58hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Forma y color:Odour SolidCarbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Forma y color:Odour SolidhCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Fórmula:C24H17Cl2N3O3S2Forma y color:SolidPeso molecular:530.446IOX2-NH2-1
CAS:IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Forma y color:SoildPeso molecular:367.36Tyrosinase-IN-26
Tyrosinase-IN-26 (compound 13) is a non-competitive inhibitor of tyrosinase, with an IC50 value of 68.86 µM. It is capable of inhibiting melanin production.Fórmula:C25H24N2O6Peso molecular:448.16344Chlorzolamide
CAS:CHLORZOLAMIDE is a sulfonamide-based inhibitor that exhibits cytotoxic effects on prostate cancer cells.Fórmula:C8H6ClN3O2S2Peso molecular:275.74Chlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Forma y color:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Forma y color:Odour SolidPeroxidase
CAS:Pureza:≥ 85units/mg (dry basis)Forma y color:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-DPP IV/hCA II-IN-1
CAS:DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).Fórmula:C17H20N2O5SForma y color:SolidPeso molecular:364.42[Asp371]-Tyrosinase (369-377), human
CAS:Tyrosinase (369-377,YMDGTMSQV) originates from tyrosinase and needs TAP and proteosome for cell presentation.Fórmula:C42H66N10O16S2Pureza:98%Forma y color:SolidPeso molecular:1031.16hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Fórmula:C22H20N4O6S2Forma y color:SolidPeso molecular:500.547CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Fórmula:C19H16ClN3O5S2Forma y color:SolidPeso molecular:465.93Trypsin, bovine origin
CAS:Pureza:≥ 2000units/mg (USP)Forma y color:White or almost white crystalline powderPeso molecular:-hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Fórmula:C20H25N3O4SForma y color:SolidPeso molecular:403.5hCAIX/XII-IN-9
hCAIX/XII-IN-9 (compound 8) is a potent inhibitor of carbonic anhydrase (CA), with Ki values of 1658 nM for hCA I, 184.8 nM for hCA II, 8.9 nM for hCA IX, and 64.8 nM for hCA XII.Fórmula:C26H25N5O5S2Peso molecular:551.12971Phenylsulfamide
CAS:Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and anFórmula:C6H8N2O2SForma y color:SolidPeso molecular:172.2Pyridine-2-aldoxime methochloride
CAS:Fórmula:C7H9N2O·ClPureza:≥ 98.0%Forma y color:White to off-white or light yellow crystalline powderPeso molecular:172.61Pyrocatechol
CAS:Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Fórmula:C6H6O2Pureza:99.96%Forma y color:SolidPeso molecular:110.11TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingForma y color:Odour Solid(Iso)-Samixogrel
CAS:(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Fórmula:C25H25ClN2O4SPureza:98.85%Forma y color:SolidPeso molecular:484.99Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFórmula:C47H64N14O10Forma y color:SolidPeso molecular:985.1Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Fórmula:C4H5NO4SForma y color:SolidPeso molecular:163.15hCA-I/hCA-II-IN-1
hCA-I/hCA-II-IN-1 (Compound P4) is a potent dual inhibitor of human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II), with Ki values of 0.22 μM and 0.33 μM respectively. hCA-I/hCA-II-IN-1 is useful for research into diseases related to CA enzymes, including glaucoma, hypertension, and ulcers.Forma y color:Odour SolidProteinase K
CAS:Pureza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Forma y color:White or almost white lyophilized powderPeso molecular:-P-Hydroxybenzoate Hydroxylase
CAS:Forma y color:Yellowish lyophilised powderPeso molecular:55 ~ 60 kDahCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Fórmula:C20H25N3O4SForma y color:SolidPeso molecular:403.5Lysozyme, from chicken egg white
CAS:Pureza:≥ 20,000U/mgForma y color:White to off-white powderPeso molecular:-Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Forma y color:Odour SolidCalmodulin-dependent Protein Kinase II fragment 290-309
CAS:Fórmula:C103H185N31O24SPeso molecular:2273.83Anhydrotetracycline hydrochloride
CAS:Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.Fórmula:C22H23ClN2O7Pureza:98% - 98.90%Forma y color:SolidPeso molecular:462.88CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Forma y color:Odour SolidhCAII-IN-8
CAS:Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Fórmula:C15H16N2O5SPureza:99.73%Forma y color:SoildPeso molecular:336.36Ref: TM-T67774
5mg42,00€1mL*10mM (DMSO)52,00€10mg64,00€25mg116,00€50mg167,00€100mg241,00€200mg339,00€Diaminopropionoyl tripeptide-33
CAS:Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].Fórmula:C17H27N7O6Pureza:98%Forma y color:SolidPeso molecular:425.44CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Forma y color:Odour SolidTPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Fórmula:C21H18N6O4SForma y color:SolidPeso molecular:450.475,6-Dihydro-2H-pyran-2-one
CAS:5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Fórmula:C5H6O2Forma y color:SolidPeso molecular:98.1Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Forma y color:Odour SolidCA Ⅱ-IN-1
CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.Fórmula:C18H19NO6SForma y color:SolidPeso molecular:377.41Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Fórmula:C15H14F3N3O4S2Pureza:98% - >99.99%Forma y color:Crystals From Dioxane SolidPeso molecular:421.41FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.Pureza:97.5%Forma y color:Lyophilized PowderPeso molecular:35.6 kDa (predicted)ErbB4 Protein, Human, Rhesus, Recombinant (hFc)
ErbB4 Protein, Human, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:96.6 kDa (predicted); 117 kDa (reducing conditions)Ref: TM-TMPY-02814
5µg77,00€10µg109,00€20µg174,00€50µg350,00€100µg668,00€200µg1.017,00€500µg2.071,00€1mg4.207,00€TrkA Protein, Canine, Recombinant (hFc)
TrkA Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:42.3 kDa (predicted); 55-61 kDa (reducing conditions)TrkB Protein, Human, Recombinant (His)
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:99.3%Forma y color:Lyophilized PowderPeso molecular:45.7 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Mer Protein, Mouse, Recombinant (His & GST)
Mer Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Forma y color:Lyophilized PowderPeso molecular:61.7 kDa (predicted); 58 kDa (reducing conditions)TrkA Protein, Rabbit, Recombinant (His)
TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:43.4 kDa (predicted)TrkB Protein, Canine, Recombinant (hFc)
TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:71.2 kDa (predicted)TrkA Protein, Rat, Recombinant (hFc)
TrkA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:69.2 kDa (predicted); 92-102 kDa (reducing conditions)Cuprizone
CAS:Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.Fórmula:C14H22N4O2Pureza:≥98%Forma y color:SolidPeso molecular:278.35
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