Hidroxilasa
Las hidroxilasas son una clase de enzimas que catalizan la hidroxilación de sustratos, añadiendo frecuentemente grupos hidroxilo (-OH) a posiciones específicas dentro de las moléculas. Estas enzimas están involucradas en una amplia variedad de rutas bioquímicas, incluyendo la síntesis de hormonas, procesos de desintoxicación y el metabolismo de fármacos. Los inhibidores y activadores de hidroxilasas son herramientas valiosas en la investigación de trastornos metabólicos, metabolismo de fármacos y regulación hormonal. En CymitQuimica, ofrecemos una selección de reactivos de hidroxilasas de alta calidad para apoyar su investigación en bioquímica, farmacología y regulación metabólica.
Se han encontrado 35 productos de "Hidroxilasa"
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Fenclonine
CAS:Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Fórmula:C9H10ClNO2Pureza:98.81% - >99.99%Forma y color:Crystals From Methanol White SolidPeso molecular:199.63ACT-678689
CAS:ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].Fórmula:C23H22ClFN6O4S2Pureza:99.46%Forma y color:SolidPeso molecular:565.04Ref: TM-T14119
1mg113,00€5mg259,00€10mg393,00€25mg655,00€50mg905,00€100mg1.216,00€200mg1.634,00€1mL*10mM (DMSO)324,00€Telotristat ethyl
CAS:Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Fórmula:C27H26ClF3N6O3Pureza:98% - 99.89%Forma y color:White SolidPeso molecular:574.98p-Ethynylphenylalanine hydrochloride
CAS:p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Fórmula:C11H12ClNO2Pureza:99.03%Forma y color:SolidPeso molecular:225.67Butobendine
CAS:Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Fórmula:C32H48N2O10Peso molecular:620.73IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Forma y color:SoildPeso molecular:367.36TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Fórmula:C21H18N6O4SForma y color:SolidPeso molecular:450.47TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingForma y color:Odour SolidGSK180
CAS:GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.Fórmula:C10H7Cl2NO4Forma y color:SolidPeso molecular:276.07Cuprizone
CAS:Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.Fórmula:C14H22N4O2Pureza:≥98%Forma y color:SolidPeso molecular:278.35FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Fórmula:C12H9ClN2O4Pureza:97.1% - >99.99%Forma y color:SolidPeso molecular:280.66Ro 61-8048
CAS:Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Fórmula:C17H15N3O6S2Pureza:98% - >99.99%Forma y color:SolidPeso molecular:421.45Ref: TM-T1896
2mg39,00€5mg57,00€10mg77,00€25mg120,00€50mg188,00€100mg299,00€200mg540,00€500mg868,00€1mL*10mM (DMSO)64,00€Telotristat
CAS:Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.Fórmula:C25H22ClF3N6O3Pureza:99.70%Forma y color:SolidPeso molecular:546.93Ref: TM-T21506
5mg48,00€10mg65,00€25mg126,00€50mg197,00€100mg320,00€200mg447,00€1mL*10mM (DMSO)55,00€p-Fluoro-L-phenylalanine
CAS:p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.Fórmula:C9H10FNO2Pureza:99.63%Forma y color:White To Off-White PowderPeso molecular:183.18Fenclonine hydrochloride
CAS:Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Fórmula:C9H11Cl2NO2Forma y color:SolidPeso molecular:236.095Telotristat Etiprate
CAS:Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.Fórmula:C27H26ClF3N6O3·C9H9NO3Pureza:99.21% - 99.83%Forma y color:White SolidPeso molecular:754.15Ref: TM-T6044
2mg46,00€5mg66,00€10mg92,00€25mg150,00€50mg183,00€100mg325,00€500mg780,00€1mL*10mM (DMSO)85,00€Tetrahydropapaverine hydrochloride
CAS:<p>Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.</p>Fórmula:C20H26ClNO4Pureza:99.08%Forma y color:White Crystal PowderPeso molecular:379.878Mildronate
CAS:Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitineFórmula:C6H14N2O2Pureza:99.94%Forma y color:White Crystalline PowderPeso molecular:146.19TETRAHYDROPIPERINE
CAS:Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.Fórmula:C17H23NO3Pureza:98.04% - 99.61%Forma y color:Off-White Low Melting Solid With Characteristic OdourPeso molecular:289.37Nepicastat
CAS:Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.Fórmula:C14H15F2N3SForma y color:SolidPeso molecular:295.35
