NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 445 productos de "NF-κB"
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Micheliolide
CAS:<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Fórmula:C15H20O3Pureza:98% - 99.37%Forma y color:SolidPeso molecular:248.32BI-69A11
CAS:<p>BI-69A11 is a dual AKT/NFkB inhibitor, increasing colon cancer cell sensitivity to mda-7/IL-24.</p>Fórmula:C25H16ClN3O2Pureza:96.97%Forma y color:SolidPeso molecular:425.87Isoquercetin
CAS:<p>1.</p>Fórmula:C21H20O12Pureza:98.08% - 99.76%Forma y color:SolidPeso molecular:464.38Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Fórmula:C21H22O5Pureza:99.03% - 99.9%Forma y color:SolidPeso molecular:354.4Articaine
CAS:<p>Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-</p>Fórmula:C13H20N2O3SForma y color:SolidPeso molecular:284.37IMM-H007
CAS:<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Fórmula:C22H23N5O8Pureza:97.73%Forma y color:SolidPeso molecular:485.45Sulfuretin
CAS:<p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>Fórmula:C15H10O5Pureza:98.91% - 99.86%Forma y color:SolidPeso molecular:270.242,5-Dihydroxyacetophenone
CAS:<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Fórmula:C8H8O3Pureza:99.75%Forma y color:Yellow PowderPeso molecular:152.15Nitidine chloride
CAS:<p>1.</p>Fórmula:C21H18ClNO4Pureza:96.59% - 98.91%Forma y color:SolidPeso molecular:383.82Flaconitine
CAS:<p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>Fórmula:C36H49NO12Pureza:98% - 99.84%Forma y color:SolidPeso molecular:687.77Vanillic Acid
CAS:<p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>Fórmula:C8H8O4Pureza:99.82%Forma y color:White Odourless Crystals Or PowderPeso molecular:168.152-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:<p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>Fórmula:C11H10N2OSPureza:99.48%Forma y color:SolidPeso molecular:218.27BOT-64
CAS:<p>BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole</p>Fórmula:C15H15NO2SPureza:99.73%Forma y color:SolidPeso molecular:273.3518α-Glycyrrhetinic acid
CAS:<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Fórmula:C30H46O4Pureza:98.54% - 99.68%Forma y color:SolidPeso molecular:470.68(E/Z)-IT-603
CAS:<p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>Fórmula:C11H9BrN2O3SPureza:99.35%Forma y color:SolidPeso molecular:329.17Asperulosidic acid
CAS:<p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>Fórmula:C18H24O12Pureza:99.47%Forma y color:SolidPeso molecular:432.38BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Fórmula:C23H26IN7O2SPureza:98% - 99.57%Forma y color:SolidPeso molecular:591.47Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Fórmula:C20H18O6Pureza:99.81%Forma y color:Off White PowderPeso molecular:354.35AS-2444697
CAS:<p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>Fórmula:C19H21ClN6O4Pureza:97.17%Forma y color:SolidPeso molecular:432.86Galloylpaeoniflorin
CAS:<p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>Fórmula:C30H32O15Pureza:99.82%Forma y color:SolidPeso molecular:632.57
