NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 383 productos de "NF-κB"
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20(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Fórmula:C42H72O13Pureza:98.11% - 99.93%Forma y color:SolidPeso molecular:785.012,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFórmula:C4H6N4OPureza:99.82%Forma y color:White Solid CrystalsPeso molecular:126.12Andrographolide
CAS:Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potentialFórmula:C20H30O5Pureza:99.39% - 99.97%Forma y color:PowderPeso molecular:350.458-Deoxygartanin
CAS:8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFórmula:C23H24O5Pureza:99.04% - 99.88%Forma y color:SolidPeso molecular:380.43TAK-243
CAS:TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).Fórmula:C19H20F3N5O5S2Pureza:98.09% - 98.93%Forma y color:SolidPeso molecular:519.52Ref: TM-T16974
1mg46,00€2mg60,00€5mg90,00€1mL*10mM (DMSO)102,00€10mg142,00€25mg254,00€50mg434,00€100mg623,00€Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Fórmula:C17H16O4Pureza:99.18% - 99.35%Forma y color:Less Transparent Liquid Colorless Transparent LiquidPeso molecular:284.31Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Fórmula:C30H48O3Pureza:98.22% - 99.7%Forma y color:White Crystalline PowderPeso molecular:456.70Indacaterol
CAS:Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.Fórmula:C24H28N2O3Pureza:99.96%Forma y color:SolidPeso molecular:392.49Rucaparib monocamsylate
CAS:Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.Fórmula:C29H34FN3O5SPureza:99.82%Forma y color:SolidPeso molecular:555.66Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Fórmula:C15H8N2O2Pureza:99.64% - 99.94%Forma y color:SolidPeso molecular:248.24Sauchinone
CAS:Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.Fórmula:C20H20O6Pureza:99.12% - >99.99%Forma y color:SolidPeso molecular:356.37Sanggenon C
CAS:Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.Fórmula:C40H36O12Pureza:97.76% - 99.76%Forma y color:SolidPeso molecular:708.71Ref: TM-T4S1615
1mg88,00€5mg178,00€10mg268,00€1mL*10mM (DMSO)269,00€25mg467,00€50mg665,00€100mg888,00€200mg1.234,00€HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFórmula:C22H22O11Pureza:97.63% - 99.66%Forma y color:SolidPeso molecular:462.40SC75741
CAS:SC75741 is a potent P65 inhibitor with IC50 of 200 nMFórmula:C29H23N7O2S2Pureza:99.44% - 99.54%Forma y color:SolidPeso molecular:565.67Ref: TM-T6661
1mg40,00€5mg73,00€1mL*10mM (DMSO)93,00€10mg105,00€25mg177,00€50mg281,00€100mg432,00€200mg618,00€Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Fórmula:C6H9NOS2Pureza:97.55% - 99.67%Forma y color:Slightly Yellowish LiquidPeso molecular:175.27Ref: TM-TL0016
1mg34,00€2mg46,00€1mL*10mM (DMSO)65,00€5mg66,00€10mg92,00€25mg167,00€50mg241,00€100mg359,00€200mg525,00€Ginsenoside Rg5
CAS:Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.Fórmula:C42H70O12Pureza:98% - 99.65%Forma y color:SolidPeso molecular:767.00Ref: TM-T6S1487
1mg107,00€5mg251,00€1mL*10mM (DMSO)341,00€10mg404,00€25mg665,00€50mg888,00€100mg1.251,00€WAY-169916
CAS:WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.Fórmula:C17H13F3N2O2Pureza:98.63% - 98.64%Forma y color:SolidPeso molecular:334.29Ref: TM-T8981
2mg39,00€5mg60,00€1mL*10mM (DMSO)89,00€10mg92,00€25mg187,00€50mg313,00€100mg450,00€200mg620,00€Astilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Fórmula:C21H22O11Pureza:97% - 99.86%Forma y color:White PowderPeso molecular:450.39Ref: TM-T2794
5mg49,00€1mL*10mM (DMSO)49,00€10mg73,00€25mg133,00€50mg212,00€100mg316,00€200mg452,00€500mg737,00€Praeruptorin A
CAS:Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulinFórmula:C21H22O7Pureza:99.63% - 99.65%Forma y color:SolidPeso molecular:386.4Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Fórmula:C30H45ClO6Pureza:98.9% - 99.53%Forma y color:SolidPeso molecular:537.13Ref: TM-T3907
2mg34,00€5mg50,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg318,00€
