NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 383 productos de "NF-κB"
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Denosumab
CAS:Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFórmula:C6404H9912N1724O2004S50Pureza:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Forma y color:LiquidPeso molecular:144.71 kDaJTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.Fórmula:C17H13NaO4Pureza:99.95%Forma y color:SolidPeso molecular:304.27Ref: TM-T8951
1mg37,00€2mg50,00€5mg65,00€1mL*10mM (DMSO)77,00€10mg95,00€25mg210,00€50mg339,00€100mg495,00€500mg1.099,00€Diethylmaleate
CAS:Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.Fórmula:C8H12O4Pureza:98%Forma y color:Colourless LiquidPeso molecular:172.18Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Fórmula:C7H4O6Pureza:99.03%Forma y color:SolidPeso molecular:184.10Ac2-26 acetate
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).Fórmula:C141H210N32O44SPureza:98%Forma y color:SolidPeso molecular:3089.43Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
Fórmula:C19H23NO4Pureza:99.02% - 99.73%Forma y color:White PowderPeso molecular:329.39ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Fórmula:C32H22O10Pureza:98% - 99.75%Forma y color:SolidPeso molecular:566.51AZD3264
CAS:AZD3264 is a new type IKK2 inhibitor.Fórmula:C21H23N5O4SPureza:98.98% - 99.17%Forma y color:SolidPeso molecular:441.5Ref: TM-T6771
1mg49,00€2mg66,00€5mg98,00€1mL*10mM (DMSO)108,00€10mg152,00€25mg295,00€50mg475,00€100mg762,00€500mg1.521,00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Fórmula:C40H52O4Pureza:95.10% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Fórmula:C29H31NO7Pureza:95.32% - 99.67%Forma y color:SolidPeso molecular:505.56Ref: TM-TQ0131
500µg155,00€1mg187,00€5mg410,00€1mL*10mM (DMSO)449,00€10mg710,00€25mg1.381,00€50mg2.352,00€Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。Fórmula:C13H12Cl2O4Pureza:98.61% - 99.85%Forma y color:Crystals Physical Description White Solid (Ntp 1992)Peso molecular:303.14Quinoclamine
CAS:Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.Fórmula:C10H6ClNO2Pureza:99.13% - 99.28%Forma y color:Orange PowderPeso molecular:207.617,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Fórmula:C15H10O4Pureza:99.39% - 99.6%Forma y color:SolidPeso molecular:254.24Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Fórmula:C19H18FN3OPureza:98.24% - 99.80%Forma y color:SolidPeso molecular:323.36Ref: TM-T4463
2mg46,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg170,00€50mg222,00€100mg344,00€200mg512,00€500mg823,00€Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Fórmula:C20H34OPureza:99.17% - ≥98%Forma y color:SolidPeso molecular:290.48Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:SolidPeso molecular:274.3614-Deoxy-11,12-didehydroandrographolide
CAS:14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.Fórmula:C20H28O4Pureza:99.13% - 99.93%Forma y color:SolidPeso molecular:332.43Ref: TM-TQ0185
1mg65,00€1mL*10mM (DMSO)138,00€5mg152,00€10mg215,00€25mg355,00€50mg530,00€100mg735,00€Rucaparib Phosphate
CAS:Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.Fórmula:C19H18FN3O·H3PO4Pureza:99.37%Forma y color:SolidPeso molecular:421.36Ref: TM-T6127
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg109,00€25mg178,00€50mg235,00€100mg371,00€200mg553,00€Damascenone
CAS:Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.Fórmula:C13H18OPureza:99.81%Forma y color:Colorless LiquidPeso molecular:190.28
