NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 385 productos de "NF-κB"
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Aconine
CAS:1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.Fórmula:C25H41NO9Pureza:99.61% - 99.93%Forma y color:SolidPeso molecular:499.59Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Fórmula:C30H48O6Pureza:98.80% - 99.69%Forma y color:SolidPeso molecular:504.70Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Fórmula:C21H28BN3O5Pureza:95.52% - 99.46%Forma y color:SolidPeso molecular:413.28Ref: TM-T6027
1mg43,00€1mL*10mM (DMSO)89,00€5mg92,00€10mg133,00€25mg260,00€50mg416,00€100mg625,00€200mg868,00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Fórmula:C19H20O6Pureza:99.6% - 99.71%Forma y color:SolidPeso molecular:344.36Aristolochic acid A
CAS:Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.Fórmula:C17H11NO7Pureza:99.85% - 99.97%Forma y color:Yellow PowderPeso molecular:341.27Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFórmula:C9H9NOPureza:98.59% - >99.99%Forma y color:SolidPeso molecular:147.173'-Sialyllactose sodium
CAS:3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis and can be used to study inflammation.Fórmula:C23H38NNaO19Pureza:>99.99%Forma y color:SolidPeso molecular:655.53(S)-(+)-Ibuprofen
CAS:(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Fórmula:C13H18O2Pureza:99.51% - 99.86%Forma y color:Colourless Crystalline SolidPeso molecular:206.28MnTBAP chloride
CAS:MnTBAP chloride: SOD mimetic, peroxynitrite scavenger, halves SOD-E. coli growth time, anti-inflammatory, may aid CKD research.Fórmula:C48H25ClMnN4O8Forma y color:SolidPeso molecular:876.13GSK-872
CAS:GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity and inhibits kinase activity.
Fórmula:C19H17N3O2S2Pureza:99.87% - 99.94%Forma y color:SolidPeso molecular:383.49Tamtuvetmab
CAS:Tamtuvetmab (AT-005), a caninised version of blontuvetmab targeting CD52, enhances progression-free survival (PFS) and demonstrates in vivo efficacy forForma y color:LiquidAnti-Mouse RANKL/CD254 Antibody (IK22/5)
Anti-MouseRANKL/CD254Antibody (IK22/5) is a rat-derived IgG2a, κ antibody inhibitor targeting the mouse RANKL/CD254.Forma y color:Odour LiquidBoserolimab
CAS:Boserolimab, Humanized anti-CD27 agonistic mAb, blocks CD70 binding to CD27, used for lung cancer research.Pureza:95% - 95%Forma y color:LiquidGatralimab
CAS:Gatralimab (anti-CD52 mAb) shows successful lymphocyte depletion & repopulation in Phase 1, supporting its study for relapsing MS.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDa1,3-Dibenzyl-5-fluorouracil
CAS:1,3-Dibenzyl-5-fluorouracil is a chemical inhibitor that suppresses the formation of osteoclasts, functioning by downregulating the signaling pathways of nuclear factor κB ligand receptor activator (Receptor activator of NF-κB ligand, RANKL) and macrophage colony-stimulating factor (M-CSF). This compound is used in the research of metabolic bone diseases.Fórmula:C18H15FN2O2Forma y color:SolidPeso molecular:310.32Kamebakaurin
CAS:Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.Fórmula:C20H30O5Pureza:98.05%Forma y color:SolidPeso molecular:350.45E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Fórmula:C21H30O6Pureza:99.52%Forma y color:SolidPeso molecular:378.46NF-κB-IN-11
CAS:NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.Fórmula:C19H18O5Pureza:98%Forma y color:SolidPeso molecular:326.34APC-0576
CAS:APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.Fórmula:C23H27N3O3Forma y color:SolidPeso molecular:393.481-Dehydro-[10]-gingerdione
CAS:1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.Fórmula:C21H30O4Forma y color:SolidPeso molecular:346.46
![1-Dehydro-[10]-gingerdione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT72208.webp&w=3840&q=75)