TLR
Los receptores tipo Toll (TLR) son una clase de proteínas que desempeñan un papel crítico en el sistema inmunitario innato al reconocer patrones moleculares asociados a patógenos (PAMP) e iniciar respuestas inmunitarias. Los TLR están involucrados en la detección de una amplia gama de patógenos, incluidos bacterias, virus y hongos, y son esenciales para la activación de las vías de señalización inflamatorias. La desregulación de la señalización de los TLR se asocia con enfermedades inflamatorias crónicas, trastornos autoinmunes y cáncer. En CymitQuimica, ofrecemos una variedad de moduladores de TLR de alta calidad para apoyar su investigación en inmunidad innata, inflamación y enfermedades infecciosas.
Se han encontrado 66 productos de "TLR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
CU-CPD107
CAS:<p>CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.</p>Fórmula:C16H21IN2O2Pureza:98%Forma y color:SolidPeso molecular:400.25TLR7 agonist 28
CAS:<p>TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.</p>Fórmula:C26H25N9O7Forma y color:SolidPeso molecular:575.533Creatine ethyl ester
CAS:<p>Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.</p>Fórmula:C6H13N3O2Forma y color:SolidPeso molecular:159.186SARM1-IN-4
CAS:<p>SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.</p>Fórmula:C13H17F2N3O2Forma y color:SolidPeso molecular:285.29LHC-165
CAS:<p>LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.</p>Fórmula:C29H32F2N3O7PPureza:98%Forma y color:SolidPeso molecular:603.55TLR7/8/9 antagonist 2
CAS:<p>TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.</p>Fórmula:C23H31N7Pureza:98%Forma y color:SoildPeso molecular:405.54
