TLR
Los receptores tipo Toll (TLR) son una clase de proteínas que desempeñan un papel crítico en el sistema inmunitario innato al reconocer patrones moleculares asociados a patógenos (PAMP) e iniciar respuestas inmunitarias. Los TLR están involucrados en la detección de una amplia gama de patógenos, incluidos bacterias, virus y hongos, y son esenciales para la activación de las vías de señalización inflamatorias. La desregulación de la señalización de los TLR se asocia con enfermedades inflamatorias crónicas, trastornos autoinmunes y cáncer. En CymitQuimica, ofrecemos una variedad de moduladores de TLR de alta calidad para apoyar su investigación en inmunidad innata, inflamación y enfermedades infecciosas.
Se han encontrado 66 productos de "TLR"
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Neoseptin-3
CAS:<p>Neoseptin-3 is a novel small molecule agonist of mouse mTLR4/MD2 with EC50=18.5 μM that does not activate human TLR4/MD2.</p>Fórmula:C29H34N2O4Pureza:98%Forma y color:SolidPeso molecular:474.59Toll-like receptor modulator
CAS:<p>Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.</p>Fórmula:C15H13F5N2O2Pureza:98%Forma y color:SolidPeso molecular:348.27Pam3CSK4
CAS:<p>Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.</p>Fórmula:C81H156N10O13SPureza:98%Forma y color:SolidPeso molecular:1510.23Bropirimine
CAS:<p>Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.</p>Fórmula:C10H8BrN3OPureza:99.01%Forma y color:SolidPeso molecular:266.09TLR7 agonist 2
CAS:<p>TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).</p>Fórmula:C17H16N6O2Pureza:99.33%Forma y color:SolidPeso molecular:336.35TLR7/8 agonist 1
CAS:<p>TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.</p>Fórmula:C22H25N5Pureza:99.4%Forma y color:SolidPeso molecular:359.47Telratolimod
CAS:<p>Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.</p>Fórmula:C36H59N5O2Pureza:98.61%Forma y color:SolidPeso molecular:593.89Enpatoran
CAS:<p>Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM).</p>Fórmula:C16H15F3N4Pureza:97.08% - 99.38%Forma y color:SolidPeso molecular:320.31Gardiquimod
CAS:<p>Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.</p>Fórmula:C17H23N5OPureza:98.02% - 99.68%Forma y color:SolidPeso molecular:313.4CU-CPT-8m
CAS:<p>CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)</p>Fórmula:C14H12N4OPureza:99.00%Forma y color:SolidPeso molecular:252.27SM-324405
CAS:<p>SM-324405 is an agonist of TLR7.</p>Fórmula:C19H23N5O4Pureza:97.83%Forma y color:SolidPeso molecular:385.42CU-CPT9b
CAS:<p>CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).</p>Fórmula:C16H13NO2Pureza:98.1%Forma y color:SolidPeso molecular:251.28MD2-IN-1
CAS:<p>MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).</p>Fórmula:C20H22O6Pureza:99.87%Forma y color:SolidPeso molecular:358.39C29
CAS:<p>C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.</p>Fórmula:C16H15NO4Pureza:96.34% - 97.37%Forma y color:SolidPeso molecular:285.29TLR3-IN-1
CAS:<p>TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.</p>Fórmula:C18H13ClFNO3SPureza:98.56%Forma y color:SolidPeso molecular:377.82CU-CPT-9a
CAS:<p>CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-</p>Fórmula:C17H15NO2Pureza:99.01%Forma y color:SolidPeso molecular:265.31TLR7/8/9-IN-1
CAS:<p>TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.</p>Fórmula:C27H37N3O2Pureza:99.56%Forma y color:SolidPeso molecular:435.6Pam3CSK4 TFA (112208-00-1 free base)
CAS:<p>Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.</p>Fórmula:C87H159F9N10O19SPureza:96.4% - 99.01%Forma y color:SolidPeso molecular:1852.33TLR4-IN-C34
CAS:<p>TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis</p>Fórmula:C17H27NO9Pureza:99.69%Forma y color:SolidPeso molecular:389.41V209
CAS:<p>1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.</p>Fórmula:C16H17N5O5Pureza:99.61%Forma y color:SolidPeso molecular:359.34
