Receptor de IL

Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.

(-)-Bornyl Acetate has an anti-inflammatory effect. It is the primary volatile ingredient in some Chinese …

Amlexanox is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, …

Dexamethasone Acetate is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent …

IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent …

Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France …

BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and …

Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.

Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exosomes …

YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of …

Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct …

Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic …

Isoferulic acid is an effective natural antioxidant in both lipid and aqueous media, it may …

Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in …

2-Aminobenzothiazole is an organic compound.

K-7174 is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 …

Dihydrocucurbitacin B is isolated from the roots of Cayaponia tayuya with anti-cancer activity.

Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity …

Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition …

Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, …

(+/-)-3,9-Dihydroeucomin has immunomodulatory effects, it shows inhibitory effects on PBMC proliferation activated by PHA with …

Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it …

Luteolin-4'-O-glucoside is an inhibitor of IL-5 (IC50 = 3.7 μM) with anti-complementary, antioxidant and anticancer …

Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, …

Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of …

Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia …

Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food …

Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential …

6,4'-Dihydroxy-7-methoxyflavanone is a biologically active compound isolated from the heartwood of Dalbergia odorifera T. Chen …

Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体,与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。

Methylnissolin is a natural product from A. membranaceus.

Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via …

Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic …

Dupilumab is a systemic immunomodulator for AD. Dupilumab is a fully human monoclonal antibody against …

Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced …

Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties …

Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly …

Agrimonolide is a potential α1 adrenergic receptor antagonist, it exerts anti-inflammatory activity, at least in …

Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane …

Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological …

Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced …

Nudiposide has significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells. It also exhibits protective …

Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and …

Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 …

Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of …

Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it …

Morusinol may significantly inhibit arterial thrombosis in vivo due to antiplatelet activity, may exert beneficial …

Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of …

Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could …

Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma …

15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on …

De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects …

1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic …

Mepolizumab is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about …

Triptoquinone A may be a useful candidate for the development of a drug as a …

Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and …

Grossamide possesses potential anti-inflammatory effects, it also has potential anti-neuroinflammatory effects against lipopolysaccharide (LPS)-induced inflammatory …

Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced …

Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in …

Guselkumab is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to …

Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin …

Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic …

3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases.

Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated …

Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen …

(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated …

Mussaenoside has anti-inflammatory action, the mechanism associated with downregulation of nuclear factor-κB.

Hydrangenol 8-O-glucoside may have anti-inflammary activity.

Ac-YVAD-CMK is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. …

Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity.

Carpinontriol B has antimicrobial activity, it at 40 ug/disk caused the formation of zones of …

Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the …

Triptoquinone B is a novel interleukin-1 inhibitor, shows extremely potent inhibitory activities against interleukin-lα and …

Esculentic acid has anti-inflammatory effect, it has protective effects against LPS-induced endotoxic shock may be …

1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for …

Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide …

Nyasol may have potential to be developed as medicines for the treatment of allergies by …

Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. …