Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 110 productos de "Receptor de IL"
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Risankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Forma y color:LiquidPeso molecular:145.85 kDaTildrakizumab
CAS:Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.Pureza:> 95%Forma y color:LiquidPeso molecular:144.44 kDaAbrezekimab
CAS:Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.Pureza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Forma y color:LiquidPeso molecular:48.1 kDaSiltuximab
CAS:Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:144.98 kDaPerakizumab
CAS:Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.Pureza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.8 kDaOrdesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Pureza:> 95%Forma y color:LiquidPeso molecular:145.12 kDaBriakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Pureza:>95%Forma y color:LiquidPeso molecular:143.86 kDaOlamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:93.14 kDaImsidolimab
CAS:Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.71 kDaSarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Pureza:97.4%Forma y color:LiquidPeso molecular:144.12 kDaPF-07038124 HCl
CAS:PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.Fórmula:C18H23BClNO4Pureza:97.34% - 99.13%Forma y color:SoildPeso molecular:363.64Brodalumab
CAS:Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.Pureza:98.3%Forma y color:LiquidPeso molecular:144.06 kDaOlokizumab
CAS:Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.39 kDaDupilumab
CAS:Dupilumab (REGN-668) is a systemic immunomodulator for AD.Pureza:95.00% - >99.2%Forma y color:LiquidPeso molecular:149.8 kDaXeligekimab
CAS:Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.Pureza:95%Forma y color:LiquidPeso molecular:147.34 kDaElsilimomab
CAS:Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.Pureza:>95%Forma y color:LiquidPeso molecular:145.96 kDaVobarilizumab
CAS:Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.Pureza:>95%Forma y color:LiquidPeso molecular:78.2 kDaBermekimab
CAS:Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.Forma y color:LiquidPeso molecular:145.45 kDa2-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Fórmula:C7H6N2SPureza:99.09% - 99.3%Forma y color:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecular:150.2IL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Fórmula:C30H36N6O4SPureza:99.16%Forma y color:SolidPeso molecular:576.71Ref: TM-T11634
1mg84,00€5mg161,00€1mL*10mM (DMSO)198,00€10mg245,00€25mg406,00€50mg572,00€100mg772,00€200mg1.035,00€Nidanilimab
CAS:Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.
Pureza:> 95%Forma y color:SoildPeso molecular:150 kDaSpesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Pureza:> 95%Forma y color:LiquidPeso molecular:150 kDaYQ128
CAS:YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.Fórmula:C27H29ClN2O4S2Pureza:99.89%Forma y color:SolidPeso molecular:545.11Ref: TM-T13375
1mg52,00€5mg113,00€1mL*10mM (DMSO)137,00€10mg177,00€25mg289,00€50mg485,00€100mg700,00€Vunakizumab
CAS:Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.Pureza:95%Forma y color:LiquidPeso molecular:146.38 kDaEnokizumab
CAS:Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.
Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Forma y color:LiquidPeso molecular:145.98 kDaIxekizumab
CAS:Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.Pureza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.2 kDaMirikizumab
CAS:Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).Pureza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.26 kDaGuselkumab
CAS:Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.Pureza:SDS-PAGE:95% SEC-HPLC:98.97%Forma y color:LiquidPeso molecular:144.8 kDaDaclizumab
CAS:Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:144.12 kDaABzOH
CAS:2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.
Fórmula:C12H10O2Pureza:99.43%Forma y color:SolidPeso molecular:186.21Reslizumab
CAS:Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:N/AEfavaleukin alfa
CAS:Efavaleukin alfa (AMG592) is a human monoclonal antibody comprising the IGHG1 Fc fragment fused to interleukin-2 (IL-2).Forma y color:LiquidStapokibart
CAS:Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.Pureza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.3 kDaCNTO 607
CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.11 kDaNosantine racemate
CAS:Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).Fórmula:C14H22N4O2Pureza:98%Forma y color:SolidPeso molecular:278.35Temtokibart
CAS:Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.Forma y color:LiquidPeso molecular:142.34 kDaMacrophage-activating lipopeptide 2 TFA
Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,Fórmula:C99H167N19O30S·xC2HF3O2Pureza:97.56%Forma y color:SolidPeso molecular:2135.56 (free base)Mepolizumab
CAS:Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.Pureza:98% - 98%Forma y color:LiquidPeso molecular:146.24 kDaTorudokimab
Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.71 kDaZiltivekimab
CAS:Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.Pureza:97.2% (SDS-PAGE); 98.9% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:SoildPeso molecular:145.39 kDaPF-06342674
PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.Forma y color:LiquidPeso molecular:145.14 kDaTriphenyl phosphate
CAS:Triphenyl phosphate is an flame retardant and endocrine disruptor that activates MAO-A/ROS/NF-κB pathways, disrupting placental tryptophan metabolism.Fórmula:C18H15O4PPureza:99.94%Peso molecular:326.288Y13g dihydrochloride
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are
Fórmula:C16H25ClN2O4Pureza:97.81%Forma y color:SoildPeso molecular:344.83Anti-inflammatory agent 42
CAS:Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.Fórmula:C20H12N2OSPureza:99.47%Forma y color:SolidPeso molecular:328.39RYTVELA TFA
CAS:RYTVELA TFA is a variant interleukin-1 receptor inhibitor with anti-inflammatory activity for the prevention of preterm labor and fetal protection.Fórmula:C38H62N10O12Forma y color:SolidPeso molecular:850.96Canakinumab
CAS:Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).
Pureza:98.8%Forma y color:LiquidPeso molecular:145.18 kDaPascolizumab
CAS:Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.Pureza:> 95%Forma y color:LiquidPeso molecular:147.18 kDaDectrekumab
CAS:Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.27 kDaMyD88-IN-1
CAS:MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.Fórmula:C23H24N6O7SPureza:99.99%Forma y color:SoildPeso molecular:528.54Ref: TM-T77353
1mg52,00€5mg156,00€1mL*10mM (DMSO)170,00€10mg225,00€25mg374,00€50mg464,00€100mg660,00€500mg1.359,00€IL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Fórmula:C33H41FN6O4Pureza:99.46%Forma y color:SolidPeso molecular:604.71
