Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 112 productos de "Receptor de IL"
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Sarilumab
CAS:<p>Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.</p>Pureza:97.4%Forma y color:LiquidPeso molecular:144.12 kDaIxekizumab
CAS:<p>Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.</p>Pureza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.2 kDaRisankizumab
CAS:<p>Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.</p>Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Forma y color:LiquidPeso molecular:145.85 kDaOlamkicept
CAS:<p>Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.</p>Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Forma y color:LiquidBrodalumab
CAS:<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Pureza:98.3%Forma y color:LiquidPeso molecular:144.06 kDaBRD6989
CAS:<p>BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.</p>Fórmula:C16H16N4Pureza:99.43%Forma y color:SolidPeso molecular:264.33Enokizumab
CAS:<p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Forma y color:LiquidPeso molecular:145.98 kDa2-Benzothiazolamine
CAS:<p>2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.</p>Fórmula:C7H6N2SPureza:99.09% - 99.3%Forma y color:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecular:150.2PF-07038124 HCl
CAS:<p>PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.</p>Fórmula:C18H23BClNO4Pureza:97.34% - 99.13%Forma y color:SoildPeso molecular:363.64Imsidolimab
CAS:<p>Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.</p>Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Forma y color:LiquidOlokizumab
CAS:<p>Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.</p>Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Forma y color:LiquidDupilumab
CAS:<p>Dupilumab (REGN-668) is a systemic immunomodulator for AD.</p>Pureza:95.00% - >99.2%Forma y color:LiquidVobarilizumab
CAS:<p>Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.</p>Pureza:>95%Forma y color:LiquidMirikizumab
CAS:<p>Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).</p>Pureza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Forma y color:LiquidXeligekimab
CAS:<p>Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.</p>Pureza:95%Forma y color:LiquidYQ128
CAS:<p>YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.</p>Fórmula:C27H29ClN2O4S2Pureza:99.89%Forma y color:SolidPeso molecular:545.11Bermekimab
CAS:<p>Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.</p>Forma y color:LiquidPeso molecular:145.45 kDaAbrezekimab
CAS:<p>Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.</p>Pureza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Forma y color:LiquidPeso molecular:48.1 kDaSiltuximab
CAS:<p>Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.</p>Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:144.98 kDaElsilimomab
CAS:<p>Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.</p>Pureza:>95%Forma y color:LiquidBriakinumab
CAS:<p>Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.</p>Pureza:>95%Forma y color:LiquidPerakizumab
CAS:<p>Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.</p>Pureza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.4 (kDa)Vunakizumab
CAS:<p>Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.</p>Pureza:95%Forma y color:LiquidLevilimab
CAS:<p>Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.</p>Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:LiquidOrdesekimab
CAS:<p>Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:145.12 kDaTildrakizumab
CAS:<p>Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:144.44 kDaAmlexanox
CAS:<p>Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.</p>Fórmula:C16H14N2O4Pureza:99.67% - ≥95%Forma y color:White Crystalline SolidPeso molecular:298.29IL-15-IN-1
CAS:<p>IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).</p>Fórmula:C30H36N6O4SPureza:99.16%Forma y color:SolidPeso molecular:576.71Spesolimab
CAS:<p>Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:150 kDaNidanilimab
CAS:<p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>Pureza:> 95%Forma y color:SoildPeso molecular:150 kDaTemtokibart
CAS:<p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>Forma y color:LiquidPeso molecular:145.5Pascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:147.18 kDaPF-06342674
<p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>Forma y color:LiquidPeso molecular:145.5kDaStapokibart
CAS:<p>Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.</p>Pureza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Forma y color:LiquidDaclizumab
CAS:<p>Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:144.12 kDaMacrophage-activating lipopeptide 2 TFA
<p>Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,</p>Fórmula:C99H167N19O30S·xC2HF3O2Pureza:97.56%Forma y color:SolidPeso molecular:2135.56 (free base)CNTO 607
<p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Forma y color:Odour LiquidAnti-inflammatory agent 42
CAS:<p>Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.</p>Fórmula:C20H12N2OSPureza:98.13%Forma y color:SolidPeso molecular:328.39Mepolizumab
CAS:<p>Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.</p>Pureza:98% - 98%Forma y color:LiquidABX-IL8
<p>ABX-IL8 is a humanized antibody targeting IL-8, capable of interfering with tube formation in human umbilical vein endothelial cells.</p>Pureza:>95%Forma y color:LiquidPeso molecular:145.5 kDaTorudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Forma y color:Odour LiquidDectrekumab
CAS:<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Forma y color:LiquidReslizumab
CAS:<p>Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.</p>Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:N/AZiltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Pureza:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:SoildGuselkumab
CAS:<p>Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.</p>Pureza:SDS-PAGE:95% SEC-HPLC:98.97%Forma y color:LiquidPeso molecular:144.8 kDaNosantine racemate
CAS:<p>Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).</p>Fórmula:C14H22N4O2Pureza:98%Forma y color:SolidPeso molecular:278.35MyD88-IN-1
CAS:<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Fórmula:C23H24N6O7SPureza:>99.99%Forma y color:SoildPeso molecular:528.54Canakinumab
CAS:<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Pureza:98.8%Forma y color:LiquidPeso molecular:145.18 kDaY13g dihydrochloride
<p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>Fórmula:C16H25ClN2O4Pureza:97.81%Forma y color:SoildPeso molecular:344.83ABzOH
CAS:<p>2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.</p>Fórmula:C12H10O2Pureza:99.43%Forma y color:SolidPeso molecular:186.21
