cAMP
cAMP es un segundo mensajero importante en muchos procesos biológicos, incluyendo la regulación del metabolismo, la expresión génica y el crecimiento celular. En la vía de señalización MAPK, cAMP puede modular la actividad de varias quinasas, incluida la PKA, que a su vez influye en la cascada MAPK. La desregulación de la señalización de cAMP está implicada en varias enfermedades, incluyendo el cáncer y los trastornos cardiovasculares. En CymitQuimica, ofrecemos una variedad de moduladores de cAMP para apoyar su investigación en transducción de señales, metabolismo y patología de enfermedades.
Se han encontrado 47 productos de "cAMP"
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HJC0197
CAS:HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.Fórmula:C19H21N3OSPureza:98.05%Forma y color:SolidPeso molecular:339.45Ref: TM-T15485
2mg38,00€5mg54,00€10mg86,00€25mg135,00€50mg188,00€100mg283,00€200mg426,00€1mL*10mM (DMSO)64,00€Bithionol
CAS:Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential toFórmula:C12H6Cl4O2SPureza:99.04%Forma y color:White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Peso molecular:356.05CE3F4
CAS:CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).Fórmula:C11H10Br2FNOPureza:97.15% - 98.06%Forma y color:SolidPeso molecular:351.01Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Fórmula:C18H23N5NaO8PPureza:96.56% - 99.76%Forma y color:White PowderPeso molecular:491.37A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.
Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22ESI-05
CAS:ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.Fórmula:C16H18O2SPureza:97.22%Forma y color:SolidPeso molecular:274.38JNJ-39758979
CAS:JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).Fórmula:C11H19N5Pureza:98.33% - 99.62%Forma y color:SolidPeso molecular:221.3Ref: TM-T11723L
1mg48,00€5mg97,00€10mg156,00€25mg255,00€50mg369,00€100mg543,00€200mg738,00€1mL*10mM (DMSO)105,00€MR-L2
CAS:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Fórmula:C19H16Cl3FN4OPureza:98.09% - 98.94%Forma y color:SolidPeso molecular:441.71Ref: TM-T12103
1mg138,00€2mg197,00€5mg334,00€10mg500,00€25mg807,00€50mg1.099,00€100mg1.485,00€500mg2.962,00€1mL*10mM (DMSO)358,00€Mirabegron
CAS:Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.Fórmula:C21H24N4O2SPureza:99.64%Forma y color:Light Yellow To Yellow SolidPeso molecular:396.51Adenosine 3'-monophosphate (sodium salt hydrate)
Adenosine 3'-monophosphate (sodium salt hydrate) (3'-AMP) is a nucleotide and cAMP-generating agonist that elevates cAMP levels in NG108-15 cells.Fórmula:C10H15N5NaO8PForma y color:SolidPeso molecular:387.22MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Fórmula:C27H29N5O5Pureza:99.00%Forma y color:SolidPeso molecular:503.55Ref: TM-T16136
1mg37,00€5mg79,00€10mg119,00€25mg235,00€50mg376,00€100mg603,00€200mg848,00€1mL*10mM (DMSO)88,00€BC 11-38
CAS:BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).Fórmula:C15H16N2OS2Pureza:98.95% - 99.28%Forma y color:SolidPeso molecular:304.43Ref: TM-T21865
1mg34,00€5mg66,00€10mg92,00€25mg192,00€50mg313,00€100mg500,00€200mg708,00€1mL*10mM (DMSO)77,00€2-PCCA hydrochloride
CAS:2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with anFórmula:C30H39Cl2N3OPureza:97.54% - 99.07%Forma y color:SoildPeso molecular:528.56Ref: TM-T80666
1mg86,00€5mg183,00€10mg259,00€25mg416,00€50mg550,00€100mg752,00€200mg1.008,00€1mL*10mM (DMSO)215,00€OX04528
CAS:OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.Fórmula:C16H13F6NO2Pureza:99.74%Forma y color:SoildPeso molecular:365.27GLP-1R modulator L7-028
CAS:GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.Fórmula:C24H28N2O3Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:392.49Anti-Cathelicidin/Camp Polyclonal Antibody
Antibody Type: Rabbit Polyclonal
Application: ELISA,ICC/IF,IF,IHC-Fr,IHC-P
Reactivity: (predicted:Mouse,Rat)Forma y color:LiquidPeso molecular:Theoretical: 19 kDa.Taprenepag
CAS:Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).Fórmula:C24H22N4O5SPureza:98.89% - 99.15%Forma y color:SolidPeso molecular:478.52Ref: TM-T3174
1mg35,00€5mg65,00€10mg97,00€25mg188,00€50mg311,00€100mg449,00€200mg628,00€1mL*10mM (DMSO)70,00€PSN 375963
CAS:PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.Fórmula:C17H23N3OPureza:99.63%Forma y color:SolidPeso molecular:285.38Ref: TM-T23204
5mg46,00€10mg65,00€25mg116,00€50mg187,00€100mg306,00€200mg437,00€1mL*10mM (DMSO)64,00€Ro 20-1724
CAS:Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1Fórmula:C15H22N2O3Pureza:98.82% - 99.79%Forma y color:SolidPeso molecular:278.35(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFórmula:C16H21NO3Pureza:99.14%Forma y color:SolidPeso molecular:275.34Cyclic AMP
CAS:cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.Fórmula:C10H12N5O6PPureza:98.01% - >99.99%Forma y color:SolidPeso molecular:329.21SAX-187
CAS:SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.Fórmula:C15H13ClN4O2S2Pureza:97.82% - 98%Forma y color:SolidPeso molecular:380.87Ref: TM-T3183
1mg79,00€5mg152,00€10mg245,00€25mg398,00€50mg532,00€100mg735,00€200mg973,00€1mL*10mM (DMSO)166,00€ESI-09
CAS:ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.Fórmula:C16H15ClN4O2Pureza:97.24% - 99.57%Forma y color:SolidPeso molecular:330.77Glaucine
CAS:Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.
Fórmula:C21H25NO4Pureza:99.42% - 99.56%Forma y color:SolidPeso molecular:355.43RS-25344 hydrochloride
CAS:RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFórmula:C19H14ClN5O4Pureza:99.25%Forma y color:SolidPeso molecular:411.8Setipiprant
CAS:Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).Fórmula:C24H19FN2O3Pureza:99.16%Forma y color:SolidPeso molecular:402.42Piclamilast
CAS:Piclamilast (RP 73401) is a PDE4 inhibitor.Fórmula:C18H18Cl2N2O3Pureza:98.28% - 99.57%Forma y color:SolidPeso molecular:381.25Pinoresinol 4-O-β-D-glucopyranoside
CAS:(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.Fórmula:C26H32O11Pureza:99.32% - >99.99%Forma y color:SolidPeso molecular:520.53Ref: TM-T4S0792
1mg50,00€5mg96,00€10mg161,00€25mg264,00€50mg370,00€100mg522,00€200mg707,00€1mL*10mM (DMSO)127,00€Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Fórmula:C22H34O7Pureza:98.83% - 99.96%Forma y color:Less Crystalline Solid Colorless Crystalline SolidPeso molecular:410.50Ref: TM-T2939
5mg43,00€10mg56,00€25mg86,00€50mg96,00€100mg144,00€200mg182,00€500mg306,00€1mL*10mM (DMSO)56,00€HJC0350
CAS:HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.Fórmula:C15H19NO2SPureza:99.27% - 99.65%Forma y color:SolidPeso molecular:277.38Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Fórmula:C12H12N2O2SPureza:98.53%Forma y color:SolidPeso molecular:248.3LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Fórmula:C7H9NO6SPureza:99% - 99.92%Forma y color:SolidPeso molecular:235.22Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.Forma y color:Lyophilized PowderPeso molecular:24.7 kDa (predicted)Ref: TM-TMPH-01058
1mg1.794,00€5µg89,00€10µg127,00€20µg204,00€50µg306,00€100µg439,00€200µg666,00€500µg1.184,00€Uliledlimab
CAS:Uliledlimab, a humanized monoclonal antibody against CD73, reduces extracellular adenosine production and modulates immunosuppressive pathways.Pureza:95% - 95.5% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:LiquidI942
CAS:I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilicalFórmula:C20H19NO4SPureza:99.86%Forma y color:SolidPeso molecular:369.43ESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.
Fórmula:C20H23N3OSPureza:97.17%Forma y color:SolidPeso molecular:353.48EPAC 5376753
CAS:EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.Fórmula:C15H8Cl2N2O3SPureza:97.48%Forma y color:SolidPeso molecular:367.21Rp-cAMPS sodium
CAS:Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.Fórmula:C10H11N5NaO5PSPureza:99.71%Forma y color:SolidPeso molecular:367.25KI-7
CAS:KI-7 is an adenosine A2B receptor positive allosteric modulator.Fórmula:C23H18N2O2Pureza:98.33%Forma y color:SolidPeso molecular:354.4Ref: TM-T9238
2mg35,00€5mg55,00€10mg95,00€25mg172,00€50mg264,00€100mg399,00€200mg560,00€1mL*10mM (DMSO)62,00€UNC0006
CAS:UNC0006 is a β-arrestin-biased dopamine D2 ligand.
Fórmula:C24H29Cl2N3O2Pureza:99.35% - 99.97%Forma y color:SolidPeso molecular:462.41Torbafylline
CAS:Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.Fórmula:C16H26N4O4Pureza:99.96% - 99.97%Forma y color:SoildPeso molecular:338.4Ref: TM-T67965
1mg81,00€5mg172,00€10mg259,00€25mg424,00€50mg583,00€100mg800,00€1mL*10mM (DMSO)178,00€CJ-42794
CAS:CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).Fórmula:C22H17ClFNO4Pureza:99.92%Forma y color:SolidPeso molecular:413.83NCGC00229600
CAS:NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.Fórmula:C30H29N3O3Pureza:99.31%Forma y color:SolidPeso molecular:479.57Ref: TM-T12192
1mg64,00€5mg145,00€10mg212,00€25mg373,00€50mg562,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)153,00€CW 008
CAS:CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.Fórmula:C21H14F2N6O2Pureza:97.39%Forma y color:SolidPeso molecular:420.37TP-10
CAS:TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.Fórmula:C26H19F3N4OPureza:99.21%Forma y color:SolidPeso molecular:460.45Ref: TM-T13189
1mg92,00€2mg120,00€5mg187,00€10mg279,00€25mg487,00€50mg705,00€100mg998,00€500mg1.882,00€1mL*10mM (DMSO)188,00€LGD-6972
CAS:LGD-6972 is an antagonist of glucagon receptor.
Fórmula:C43H46N2O5SPureza:98.8% - 99.62%Forma y color:SolidPeso molecular:702.9Vidupiprant
CAS:Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.Fórmula:C28H27Cl2FN2O6SPureza:98.88%Forma y color:SolidPeso molecular:609.49Ref: TM-T17232
1mg63,00€5mg137,00€10mg207,00€25mg375,00€50mg560,00€100mg797,00€500mg1.603,00€1mL*10mM (DMSO)178,00€
