cAMP
cAMP es un segundo mensajero importante en muchos procesos biológicos, incluyendo la regulación del metabolismo, la expresión génica y el crecimiento celular. En la vía de señalización MAPK, cAMP puede modular la actividad de varias quinasas, incluida la PKA, que a su vez influye en la cascada MAPK. La desregulación de la señalización de cAMP está implicada en varias enfermedades, incluyendo el cáncer y los trastornos cardiovasculares. En CymitQuimica, ofrecemos una variedad de moduladores de cAMP para apoyar su investigación en transducción de señales, metabolismo y patología de enfermedades.
Se han encontrado 47 productos de "cAMP"
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HJC0197
CAS:<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Fórmula:C19H21N3OSPureza:98.05%Forma y color:SolidPeso molecular:339.45Bithionol
CAS:<p>Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to</p>Fórmula:C12H6Cl4O2SPureza:99.04%Forma y color:White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Peso molecular:356.05CE3F4
CAS:<p>CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).</p>Fórmula:C11H10Br2FNOPureza:97.15% - 98.06%Forma y color:SolidPeso molecular:351.01Bucladesine sodium
CAS:<p>Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.</p>Fórmula:C18H23N5NaO8PPureza:96.56% - 99.76%Forma y color:White PowderPeso molecular:491.37A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22ESI-05
CAS:<p>ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.</p>Fórmula:C16H18O2SPureza:97.22%Forma y color:SolidPeso molecular:274.38JNJ-39758979
CAS:<p>JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).</p>Fórmula:C11H19N5Pureza:98.33% - 99.62%Forma y color:SolidPeso molecular:221.3MR-L2
CAS:<p>MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).</p>Fórmula:C19H16Cl3FN4OPureza:98.09% - 98.94%Forma y color:SolidPeso molecular:441.71Mirabegron
CAS:<p>Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.</p>Fórmula:C21H24N4O2SPureza:99.64%Forma y color:Light Yellow To Yellow SolidPeso molecular:396.51Adenosine 3'-monophosphate (sodium salt hydrate)
<p>Adenosine 3'-monophosphate (sodium salt hydrate) (3'-AMP) is a nucleotide and cAMP-generating agonist that elevates cAMP levels in NG108-15 cells.</p>Fórmula:C10H15N5NaO8PForma y color:SolidPeso molecular:387.22MRS-1706
CAS:<p>MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.</p>Fórmula:C27H29N5O5Pureza:99.00%Forma y color:SolidPeso molecular:503.55BC 11-38
CAS:<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Fórmula:C15H16N2OS2Pureza:98.95% - 99.28%Forma y color:SolidPeso molecular:304.432-PCCA hydrochloride
CAS:<p>2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an</p>Fórmula:C30H39Cl2N3OPureza:97.54% - 99.36%Forma y color:SoildPeso molecular:528.56OX04528
CAS:<p>OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.</p>Fórmula:C16H13F6NO2Pureza:99.74%Forma y color:SoildPeso molecular:365.27GLP-1R modulator L7-028
CAS:<p>GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.</p>Fórmula:C24H28N2O3Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:392.49Anti-Cathelicidin/Camp Polyclonal Antibody
<p>Antibody Type: Rabbit Polyclonal<br><br>Application: IHC-P,IHC-Fr,ICC/IF,IF,ELISA<br><br>Reactivity: (predicted:Mouse,Rat)</p>Forma y color:LiquidPeso molecular:Theoretical: 19 kDa.Taprenepag
CAS:<p>Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).</p>Fórmula:C24H22N4O5SPureza:98.89% - 99.15%Forma y color:SolidPeso molecular:478.52PSN 375963
CAS:<p>PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.</p>Fórmula:C17H23N3OPureza:99.63%Forma y color:SolidPeso molecular:285.38Ro 20-1724
CAS:<p>Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1</p>Fórmula:C15H22N2O3Pureza:98.82% - 99.79%Forma y color:SolidPeso molecular:278.35(S)-(+)-Rolipram
CAS:<p>(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the</p>Fórmula:C16H21NO3Pureza:99.14%Forma y color:SolidPeso molecular:275.34Cyclic AMP
CAS:<p>cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.</p>Fórmula:C10H12N5O6PPureza:98.01% - >99.99%Forma y color:SolidPeso molecular:329.21SAX-187
CAS:<p>SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.</p>Fórmula:C15H13ClN4O2S2Pureza:97.82% - 98%Forma y color:SolidPeso molecular:380.87ESI-09
CAS:<p>ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.</p>Fórmula:C16H15ClN4O2Pureza:97.24% - 99.57%Forma y color:SolidPeso molecular:330.77Glaucine
CAS:<p>Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.</p>Fórmula:C21H25NO4Pureza:99.42% - 99.56%Forma y color:SolidPeso molecular:355.43RS-25344 hydrochloride
CAS:<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Fórmula:C19H14ClN5O4Pureza:99.25%Forma y color:SolidPeso molecular:411.8Setipiprant
CAS:<p>Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).</p>Fórmula:C24H19FN2O3Pureza:99.16%Forma y color:SolidPeso molecular:402.42Piclamilast
CAS:<p>Piclamilast (RP 73401) is a PDE4 inhibitor.</p>Fórmula:C18H18Cl2N2O3Pureza:98.28% - 99.57%Forma y color:SolidPeso molecular:381.25Pinoresinol 4-O-β-D-glucopyranoside
CAS:<p>(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.</p>Fórmula:C26H32O11Pureza:99.32% - >99.99%Forma y color:SolidPeso molecular:520.53Forskolin
CAS:<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Fórmula:C22H34O7Pureza:98.83% - 99.96%Forma y color:Less Crystalline Solid Colorless Crystalline SolidPeso molecular:410.5HJC0350
CAS:<p>HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.</p>Fórmula:C15H19NO2SPureza:99.27% - 99.65%Forma y color:SolidPeso molecular:277.38Enoximone
CAS:<p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>Fórmula:C12H12N2O2SPureza:98.53%Forma y color:SolidPeso molecular:248.3LY404039
CAS:<p>LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).</p>Fórmula:C7H9NO6SPureza:99% - 99.92%Forma y color:SolidPeso molecular:235.22Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
<p>Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.</p>Forma y color:Lyophilized PowderPeso molecular:24.7 kDa (predicted)Uliledlimab
CAS:<p>Uliledlimab, a humanized monoclonal antibody against CD73, reduces extracellular adenosine production and modulates immunosuppressive pathways.</p>Pureza:95% - 95%Forma y color:LiquidI942
CAS:<p>I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical</p>Fórmula:C20H19NO4SPureza:99.75%Forma y color:SolidPeso molecular:369.43ESI-08
CAS:<p>ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.</p>Fórmula:C20H23N3OSPureza:97.17%Forma y color:SolidPeso molecular:353.48EPAC 5376753
CAS:<p>EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.</p>Fórmula:C15H8Cl2N2O3SPureza:97.48%Forma y color:SolidPeso molecular:367.21Rp-cAMPS sodium
CAS:<p>Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.</p>Fórmula:C10H11N5NaO5PSPureza:99.71%Forma y color:SolidPeso molecular:367.25KI-7
CAS:<p>KI-7 is an adenosine A2B receptor positive allosteric modulator.</p>Fórmula:C23H18N2O2Pureza:98.33%Forma y color:SolidPeso molecular:354.4UNC0006
CAS:<p>UNC0006 is a β-arrestin-biased dopamine D2 ligand.</p>Fórmula:C24H29Cl2N3O2Pureza:99.35% - 99.97%Forma y color:SolidPeso molecular:462.41Torbafylline
CAS:<p>Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.</p>Fórmula:C16H26N4O4Pureza:98.66% - 99.13%Forma y color:SoildPeso molecular:338.4CJ-42794
CAS:<p>CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).</p>Fórmula:C22H17ClFNO4Pureza:99.92%Forma y color:SolidPeso molecular:413.83NCGC00229600
CAS:<p>NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.</p>Fórmula:C30H29N3O3Pureza:99.31%Forma y color:SolidPeso molecular:479.57CW 008
CAS:<p>CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.</p>Fórmula:C21H14F2N6O2Pureza:97.39%Forma y color:SolidPeso molecular:420.37TP-10
CAS:<p>TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.</p>Fórmula:C26H19F3N4OPureza:99.21%Forma y color:SolidPeso molecular:460.45LGD-6972
CAS:<p>LGD-6972 is an antagonist of glucagon receptor.</p>Fórmula:C43H46N2O5SPureza:98.8% - 99.62%Forma y color:SolidPeso molecular:702.9Vidupiprant
CAS:<p>Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.</p>Fórmula:C28H27Cl2FN2O6SPureza:98.88%Forma y color:SolidPeso molecular:609.49
