cAMP
cAMP es un segundo mensajero importante en muchos procesos biológicos, incluyendo la regulación del metabolismo, la expresión génica y el crecimiento celular. En la vía de señalización MAPK, cAMP puede modular la actividad de varias quinasas, incluida la PKA, que a su vez influye en la cascada MAPK. La desregulación de la señalización de cAMP está implicada en varias enfermedades, incluyendo el cáncer y los trastornos cardiovasculares. En CymitQuimica, ofrecemos una variedad de moduladores de cAMP para apoyar su investigación en transducción de señales, metabolismo y patología de enfermedades.
Se han encontrado 47 productos para "cAMP".
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MR-L2
CAS:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Fórmula:C19H16Cl3FN4OPureza:98.09% - 98.94%Forma y color:SolidPeso molecular:441.71Ref: TM-T12103
1mg138,00€2mg197,00€5mg334,00€1mL*10mM (DMSO)358,00€10mg500,00€25mg807,00€50mg1.099,00€100mg1.485,00€500mg2.962,00€Mirabegron
CAS:Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.Fórmula:C21H24N4O2SPureza:99.64%Forma y color:SolidPeso molecular:396.51Bithionol
CAS:Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential toFórmula:C12H6Cl4O2SPureza:99.04%Forma y color:SolidPeso molecular:356.05JNJ-39758979
CAS:JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).Fórmula:C11H19N5Pureza:98.33% - 99.62%Forma y color:SolidPeso molecular:221.3Ref: TM-T11723L
1mg46,00€5mg92,00€1mL*10mM (DMSO)100,00€10mg147,00€25mg241,00€50mg350,00€100mg515,00€200mg700,00€ESI-05
CAS:ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.Fórmula:C16H18O2SPureza:97.22%Forma y color:SolidPeso molecular:274.38A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Fórmula:C18H23N5NaO8PPureza:96.56% - 99.76%Forma y color:White SolidPeso molecular:491.37HJC0197
CAS:HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.Fórmula:C19H21N3OSPureza:98.05%Forma y color:SolidPeso molecular:339.45Ref: TM-T15485
2mg35,00€5mg51,00€1mL*10mM (DMSO)60,00€10mg81,00€25mg128,00€50mg178,00€100mg268,00€200mg404,00€CE3F4
CAS:CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).Fórmula:C11H10Br2FNOPureza:97.15% - 98.06%Forma y color:White SolidPeso molecular:351.01OX04528
CAS:OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.Fórmula:C16H13F6NO2Pureza:99.74%Forma y color:White SolidPeso molecular:365.27Motapizone
CAS:Motapizone (NAT 05-239) is a selective PDE3 inhibitor that suppresses cytokine release, increases intracellular cAMP, and inhibits human platelet aggregation.Fórmula:C12H12N4OSPureza:95.26%Forma y color:Red SolidPeso molecular:260.32MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Fórmula:C27H29N5O5Pureza:99.00%Forma y color:SolidPeso molecular:503.55Ref: TM-T16136
1mg34,00€5mg74,00€1mL*10mM (DMSO)84,00€10mg113,00€25mg222,00€50mg356,00€100mg572,00€200mg803,00€2-PCCA hydrochloride
CAS:2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with anFórmula:C30H39Cl2N3OPureza:99.07% - 99.9%Forma y color:SolidPeso molecular:528.56Ref: TM-T80666
1mg81,00€5mg173,00€1mL*10mM (DMSO)203,00€10mg245,00€25mg394,00€50mg520,00€100mg712,00€200mg954,00€BC 11-38
CAS:BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).Fórmula:C15H16N2OS2Pureza:98.95% - 99.28%Forma y color:SolidPeso molecular:304.43Ref: TM-T21865
1mg34,00€5mg66,00€1mL*10mM (DMSO)77,00€10mg92,00€25mg192,00€50mg313,00€100mg500,00€200mg708,00€GLP-1R modulator L7-028
CAS:GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.Fórmula:C24H28N2O3Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:392.49Anti-Cathelicidin/Camp Polyclonal Antibody
Antibody Type: Rabbit Polyclonal
Application: ELISA,ICC/IF,IF,IHC-Fr,IHC-P
Reactivity: (predicted:Mouse,Rat)Forma y color:LiquidPeso molecular:Theoretical: 19 kDa.Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Fórmula:C22H34O7Pureza:98.83% - 99.86%Forma y color:White SolidPeso molecular:410.50Ref: TM-T2939
5mg40,00€1mL*10mM (DMSO)44,00€10mg52,00€25mg81,00€50mg90,00€100mg137,00€200mg172,00€500mg290,00€Taprenepag
CAS:Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).Fórmula:C24H22N4O5SPureza:98.89% - 99.45%Forma y color:SolidPeso molecular:478.52Ref: TM-T3174
1mg34,00€5mg62,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg178,00€50mg295,00€100mg425,00€200mg595,00€Pinoresinol 4-O-β-D-glucopyranoside
CAS:(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.Fórmula:C26H32O11Pureza:99.32% - >99.99%Forma y color:SolidPeso molecular:520.53ESI-09
CAS:ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.Fórmula:C16H15ClN4O2Pureza:97.24% - 99.57%Forma y color:SolidPeso molecular:330.77SAX-187
CAS:SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.Fórmula:C15H13ClN4O2S2Pureza:97.82% - 98%Forma y color:SolidPeso molecular:380.87Ref: TM-T3183
1mg79,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg245,00€25mg398,00€50mg532,00€100mg735,00€200mg973,00€Cyclic AMP
CAS:cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.Fórmula:C10H12N5O6PPureza:98.01% - >99.99%Forma y color:White SolidPeso molecular:329.21Ro 20-1724
CAS:Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1Fórmula:C15H22N2O3Pureza:98.82% - 99.79%Forma y color:SolidPeso molecular:278.35Glaucine
CAS:Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.Fórmula:C21H25NO4Pureza:99.42% - 99.56%Forma y color:White SolidPeso molecular:355.43PSN 375963
CAS:PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.Fórmula:C17H23N3OPureza:99.63%Forma y color:SolidPeso molecular:285.38(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFórmula:C16H21NO3Pureza:99.14%Forma y color:SolidPeso molecular:275.34RS-25344 hydrochloride
CAS:RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFórmula:C19H14ClN5O4Pureza:99.25%Forma y color:SolidPeso molecular:411.8Setipiprant
CAS:Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).Fórmula:C24H19FN2O3Pureza:99.16%Forma y color:White SolidPeso molecular:402.42Piclamilast
CAS:Piclamilast (RP 73401) is a PDE4 inhibitor.Fórmula:C18H18Cl2N2O3Pureza:98.28% - 99.57%Forma y color:White SolidPeso molecular:381.25HJC0350
CAS:HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.Fórmula:C15H19NO2SPureza:99.27% - 99.65%Forma y color:SolidPeso molecular:277.38Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Fórmula:C12H12N2O2SPureza:98.53%Forma y color:SolidPeso molecular:248.3LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Fórmula:C7H9NO6SPureza:99% - 99.92%Forma y color:SolidPeso molecular:235.22Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.Forma y color:Lyophilized PowderPeso molecular:24.7 kDa (predicted)Ref: TM-TMPH-01058
5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€1mg1.648,00€Uliledlimab
CAS:Uliledlimab, a humanized monoclonal antibody against CD73, reduces extracellular adenosine production and modulates immunosuppressive pathways.Pureza:95% - 95.5% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:145.02 kDaESI-08
CAS:ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.Fórmula:C20H23N3OSPureza:97.17%Forma y color:White SolidPeso molecular:353.48I942
CAS:I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilicalFórmula:C20H19NO4SPureza:99.86%Forma y color:SolidPeso molecular:369.43EPAC 5376753
CAS:EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.Fórmula:C15H8Cl2N2O3SPureza:97.48%Forma y color:SolidPeso molecular:367.21Torbafylline
CAS:Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.Fórmula:C16H26N4O4Pureza:99.96% - 99.97%Forma y color:SoildPeso molecular:338.4Ref: TM-T67965
1mg81,00€5mg172,00€1mL*10mM (DMSO)178,00€10mg259,00€25mg424,00€50mg583,00€100mg800,00€KI-7
CAS:KI-7 is an adenosine A2B receptor positive allosteric modulator.Fórmula:C23H18N2O2Pureza:98.33%Forma y color:SolidPeso molecular:354.4Ref: TM-T9238
2mg35,00€5mg55,00€1mL*10mM (DMSO)62,00€10mg95,00€25mg172,00€50mg264,00€100mg399,00€200mg560,00€UNC0006
CAS:UNC0006 is a β-arrestin-biased dopamine D2 ligand.Fórmula:C24H29Cl2N3O2Pureza:99.35% - 99.97%Forma y color:White OilPeso molecular:462.41CW 008
CAS:CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.Fórmula:C21H14F2N6O2Pureza:97.39%Forma y color:Yellow SolidPeso molecular:420.37CJ-42794
CAS:CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).Fórmula:C22H17ClFNO4Pureza:99.92%Forma y color:SolidPeso molecular:413.83NCGC00229600
CAS:NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.Fórmula:C30H29N3O3Pureza:99.31%Forma y color:Yellow SolidPeso molecular:479.57Ref: TM-T12192
1mg60,00€5mg138,00€1mL*10mM (DMSO)144,00€10mg200,00€25mg353,00€50mg532,00€100mg773,00€Vidupiprant
CAS:Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.Fórmula:C28H27Cl2FN2O6SPureza:98.88%Forma y color:SolidPeso molecular:609.49Ref: TM-T17232
1mg63,00€5mg137,00€1mL*10mM (DMSO)178,00€10mg207,00€25mg375,00€50mg560,00€100mg797,00€500mg1.603,00€LGD-6972
CAS:LGD-6972 is an antagonist of glucagon receptor.Fórmula:C43H46N2O5SPureza:98.8% - 99.62%Forma y color:SolidPeso molecular:702.9Ref: TM-T11845
1mg84,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)268,00€25mg447,00€50mg655,00€100mg888,00€TP-10
CAS:TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.Fórmula:C26H19F3N4OPureza:99.21%Forma y color:SolidPeso molecular:460.45Ref: TM-T13189
1mg87,00€2mg114,00€5mg177,00€1mL*10mM (DMSO)178,00€10mg264,00€25mg460,00€50mg668,00€100mg945,00€500mg1.783,00€Sperm motility agonist-2
CAS:Sperm motility agonist-2 is a potent sAC agonist; elevates cAMP to enhance sperm motility; used in fertility research.Fórmula:C16H15ClN2O2SPureza:99.67%Peso molecular:334.82
