MAPK
Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.
Se han encontrado 896 productos de "MAPK"
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Cefotetan
CAS:Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.Fórmula:C17H17N7O8S4Pureza:95.72% - 99.38%Forma y color:SolidPeso molecular:575.62SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Fórmula:C24H28N2O9SPureza:95.65%Forma y color:SolidPeso molecular:520.55GSK-114
CAS:GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.Fórmula:C19H23N5O4SPureza:99.51%Forma y color:SolidPeso molecular:417.48CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Fórmula:C24H15F2N3Pureza:98.79%Forma y color:SolidPeso molecular:383.39Bimiralisib
CAS:Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Fórmula:C17H20F3N7O2Pureza:97.58% - 98.92%Forma y color:SolidPeso molecular:411.38Compound 3344 hydrochloride
<p>Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions，with an affnity of 126nm.</p>Fórmula:C24H27ClN2O3Pureza:99.23%Forma y color:SolidPeso molecular:426.94p-Cresyl sulfate potassium
CAS:p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanineFórmula:C7H7KO4SPureza:99.38% - 99.90%Forma y color:SolidPeso molecular:226.29BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Fórmula:C22H26N6O2Pureza:98.11%Forma y color:SolidPeso molecular:406.48Rasarfin
CAS:Rasarfin inhibits Ras and ARF6.Fórmula:C23H24ClN3O3Pureza:97.98%Forma y color:SolidPeso molecular:425.91ZT-12-037-01
CAS:Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Fórmula:C21H31N5O2Pureza:99.56%Forma y color:SolidPeso molecular:385.5DB07268
CAS:<p>DB07268 is a potent and selective JNK1 inhibitor.</p>Fórmula:C17H15N5O2Pureza:98.2% - 98.91%Forma y color:SolidPeso molecular:321.33Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Fórmula:C8H10NO6PPureza:97.52%Forma y color:SolidPeso molecular:247.14BI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Fórmula:C19H23F2N5O2Pureza:98.51% - 99.43%Forma y color:SolidPeso molecular:391.42Skepinone-L
CAS:<p>Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.</p>Fórmula:C24H21F2NO4Pureza:99.56% - >99.99%Forma y color:SolidPeso molecular:425.42PF-06260933 HCl
CAS:PF-06260933 Dihydrochloride, a MAP4K4 inhibitor, hinders HGK, Mink, Tnik (IC50s: 140, 8, 13 nM) and lessens mouse fasting hyperglycemia.Fórmula:C16H15Cl3N4Forma y color:SolidPeso molecular:369.68CC-90001
CAS:CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.Fórmula:C16H27N5O2Pureza:99.96%Forma y color:SolidPeso molecular:321.42NG25 trihydrochloride
CAS:NG25 trihydrochloride: kinase inhibitor for MAP4K2, TAK1, Src, LYN, Abl, CSK, FER, p38α; blocks TNF-α signals; impedes IFN secretion; anti-cancer properties.Fórmula:C29H33Cl3F3N5O2Forma y color:SolidPeso molecular:646.96Belvarafenib TFA
<p>Belvarafenib TFA (HM95573 TFA) inhibits RAF: B-RAF (56 nM), B-RAFv600E (7 nM), C-RAF (5 nM) effectively.</p>Fórmula:C25H17ClF4N6O3SForma y color:SolidPeso molecular:592.95JNK-IN-8
CAS:JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).Fórmula:C29H29N7O2Pureza:99.24% - >99.99%Forma y color:SolidPeso molecular:507.59ARS-1620
CAS:<p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>Fórmula:C21H17ClF2N4O2Pureza:98.86%Forma y color:SolidPeso molecular:430.84
