MAPK
Las MAPK son una familia de quinasas de proteínas involucradas en una variedad de procesos celulares, incluyendo crecimiento, proliferación, diferenciación y respuestas al estrés. La vía de señalización MAPK consta de varios niveles, incluidos ERK, JNK y p38 MAPK, cada uno con roles distintos en la función celular. La desregulación de la señalización MAPK está vinculada al cáncer, las enfermedades inflamatorias y los trastornos metabólicos. En CymitQuimica, ofrecemos una amplia gama de inhibidores y activadores de MAPK para apoyar su investigación en biología celular, transducción de señales y mecanismos de enfermedades.
Se han encontrado 893 productos de "MAPK"
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Angiogenesis inhibitor BT2
CAS:BT2 inhibits angiogenesis, vascular permeability by targeting ERK, FosB, VCAM-1, and related genes, affecting MEK1 and suppressing retinal markers.Fórmula:C18H18N2O4Forma y color:SolidPeso molecular:326.35J30-8
CAS:J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used to study neurodegenerative diseases such as Alzheimer's disease.Fórmula:C17H9ClFN3O2SPureza:99.90%Forma y color:SolidPeso molecular:373.79TAK1/MAP4K2 inhibitor 1
CAS:TAK1/MAP4K2 inhibitor 1 (compound 5) is a dual kinase inhibitor of TAK1 and MAP4K2 with IC50 values of 41.1 nM and 18.2 nM, respectively.Fórmula:C29H31F3N6O2Pureza:98%Forma y color:SolidPeso molecular:552.59RMM-46
CAS:<p>RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.</p>Fórmula:C24H26N4O5Pureza:98.89%Forma y color:SolidPeso molecular:450.49LY-2584702 hydrochloride
CAS:<p>Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.</p>Fórmula:C21H20ClF4N7Pureza:98%Forma y color:SolidPeso molecular:481.88MEK inhibitor
CAS:MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.Fórmula:C26H26N4O2Pureza:97.48%Forma y color:SolidPeso molecular:426.51NSC-70220
CAS:SOS1-IN-1 is an inhibitor of SOS1.Fórmula:C22H15NO2Pureza:98%Forma y color:SolidPeso molecular:325.36MNK1/2-IN-5
CAS:MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used to study solid tumors and hematological malignancies.Fórmula:C17H16N4O2Pureza:98.04%Forma y color:SolidPeso molecular:308.33MEK-IN-4
CAS:<p>MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.</p>Fórmula:C21H18N4OSPureza:98.35% - 99.16%Forma y color:SolidPeso molecular:374.46Nek2-IN-5
CAS:Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).Fórmula:C15H12N6OPureza:98.11%Forma y color:SolidPeso molecular:292.3mSIRK
CAS:mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit dissociation.Fórmula:C93H150N20O25Pureza:99.26%Forma y color:SolidPeso molecular:1948.31BI-2852
CAS:BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.Fórmula:C31H28N6O2Pureza:98.98%Forma y color:SolidPeso molecular:516.59RMC-0331
CAS:RMC-0331 (RM-023) is an oral SOS1 inhibitor with potential to block RAS activation and anticancer properties.Fórmula:C22H25ClF3N5O3Pureza:97.84%Forma y color:SolidPeso molecular:499.91ZINC12409120
CAS:ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23Fórmula:C20H16N4O2Pureza:99.71% - 99.95%Forma y color:SolidPeso molecular:344.37JNK-IN-11
CAS:JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.Fórmula:C12H11NO3S2Pureza:98.82%Forma y color:SolidPeso molecular:281.35MKK7-COV-9
CAS:MKK7-COV-9 is an MKK7 inhibitor that inhibits MKK7-induced protein-protein interactions and interrupts the activation of primary B cells in response to LPS.Fórmula:C18H16N4O2Pureza:99.73% - 99.83%Forma y color:SolidPeso molecular:320.35UR13870
CAS:<p>UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.</p>Fórmula:C24H16F2N4Pureza:99.18% - >99.99%Forma y color:SolidPeso molecular:398.41DS12881479
CAS:DS12881479 can be used in cancer research which is a potent and selective inhibitor of Mnk1(IC 50 =21 nM) [1].Fórmula:C16H19N3OSPureza:99.85%Forma y color:SolidPeso molecular:301.41GSK2008607
CAS:<p>GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers.</p>Fórmula:C31H28F3N7O3S2Pureza:99.36%Forma y color:SolidPeso molecular:667.72(E)-GABAB receptor antagonist 1
CAS:(E)-GABAB antagonist 1 inhibits GABA IP3 production, with an IC50 of 37.9 μM and acts as a selective negative modulator.Fórmula:C18H24O4Pureza:98.09%Forma y color:SolidPeso molecular:304.38
