ERK
ERK es una proteína clave en la vía de señalización MAPK (Mitogen-Activated Protein Kinase), que está involucrada en la transmisión de señales desde los receptores de la superficie celular hasta el ADN en el núcleo celular. ERK juega un papel crucial en la regulación de varios procesos celulares, incluyendo la proliferación, diferenciación y supervivencia. La desregulación de la señalización ERK está asociada con el desarrollo de cáncer y otras enfermedades, lo que la convierte en un objetivo importante para la intervención terapéutica. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de ERK de alta calidad para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 223 productos para "ERK".
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Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Fórmula:C17H17ClF6N2OPureza:99% - 99.99%Forma y color:SolidPeso molecular:414.77MK2-IN-3 hydrate
CAS:MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)Fórmula:C21H18N4O2Pureza:99.58%Forma y color:SolidPeso molecular:358.39Ref: TM-T12058
1mg34,00€5mg60,00€1mL*10mM (DMSO)73,00€10mg87,00€25mg172,00€50mg250,00€100mg350,00€200mg480,00€LUT014
CAS:LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.Fórmula:C27H19F3N8OPureza:99.03%Forma y color:Yellow SolidPeso molecular:528.49Methylthiouracil
CAS:Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.Fórmula:C5H6N2OSPureza:98.82% - 99.89%Forma y color:SolidPeso molecular:142.18Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Fórmula:C14H23ClN2OPureza:99.83% - 99.92%Forma y color:SolidPeso molecular:270.798ERK5-IN-6
CAS:ERK5-IN-6 is an ERK5 kinase inhibitor with antiproliferative, anticonvulsant, and antitumor activity for the study of central nervous system related diseases.Fórmula:C23H21N3Pureza:99.87%Forma y color:SolidPeso molecular:339.43AX-15836
CAS:AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).Fórmula:C32H40N8O5SPureza:98.96%Forma y color:SolidPeso molecular:648.78Ref: TM-T14360
1mg54,00€2mg77,00€5mg114,00€1mL*10mM (DMSO)164,00€10mg167,00€25mg281,00€50mg401,00€100mg567,00€500mg1.161,00€Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Fórmula:C17H16F6N2OPureza:99.89%Forma y color:SolidPeso molecular:378.31Ref: TM-T0860L
1mg66,00€5mg145,00€1mL*10mM (DMSO)152,00€10mg213,00€25mg356,00€50mg510,00€100mg715,00€200mg964,00€CC-90003
CAS:CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.Fórmula:C22H21F3N6O2Pureza:99.42%Forma y color:SolidPeso molecular:458.44Ref: TM-T14894
2mg35,00€1mg46,00€5mg50,00€1mL*10mM (DMSO)50,00€10mg86,00€25mg156,00€50mg215,00€100mg319,00€PD 198306
CAS:PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.Fórmula:C18H16F3IN2O2Pureza:99.66%Forma y color:SolidPeso molecular:476.23Ref: TM-T21980
1mg60,00€5mg131,00€1mL*10mM (DMSO)152,00€10mg178,00€25mg314,00€50mg447,00€100mg622,00€500mg1.224,00€Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Fórmula:C14H22N2OPureza:99.88% - >99.99%Forma y color:White SolidPeso molecular:234.34ERK5-IN-5
CAS:ERK5-IN-5 is extracellular signal-regulated kinase 5 (ERK5) inhibitor with anticancer activity anticonvulsant activity inhibits A549 cell proliferation.Fórmula:C19H16ClN3OPureza:99.89%Forma y color:SolidPeso molecular:337.8Ref: TM-T77734
1mg81,00€2mg105,00€5mg170,00€10mg264,00€25mg532,00€50mg868,00€100mg1.378,00€500mg2.673,00€MRTX-1257
CAS:MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% target engagement.Fórmula:C33H39N7O2Pureza:96.76% - 97.3%Forma y color:Yellow SolidPeso molecular:565.71Ref: TM-T16143
1mg60,00€2mg85,00€5mg124,00€1mL*10mM (DMSO)166,00€10mg195,00€25mg351,00€50mg512,00€100mg743,00€200mg982,00€(E/Z)-BCI
CAS:(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFórmula:C22H23NOPureza:99.94%Forma y color:White SolidPeso molecular:317.42Ref: TM-T11139
1mg56,00€5mg119,00€1mL*10mM (DMSO)129,00€10mg170,00€25mg290,00€50mg432,00€100mg620,00€Honokiol
CAS:Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.Fórmula:C18H18O2Pureza:99.65% - 99.94%Forma y color:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TastePeso molecular:266.33Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Forma y color:SolidPeso molecular:288.82BAY 2965501
CAS:BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer.Fórmula:C20H19FN4O3SPureza:99.89%Forma y color:SolidPeso molecular:414.45Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFórmula:C13H8O3Pureza:99.45%Forma y color:SolidPeso molecular:212.2Rineterkib hydrochloride
CAS:Rineterkib hydrochloride (B) is an oral RAF/ERK1/2 inhibitor for MAPK-driven cancers, including KRAS/BRAF-mutant NSCLC and CRC.Fórmula:C26H28BrClF3N5O2Forma y color:SolidPeso molecular:614.89VSLRGDTRG
CAS:VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.Fórmula:C38H69N15O14Forma y color:SolidPeso molecular:960.047
