Raf
Las quinasas Raf son componentes clave de la vía de señalización MAPK/ERK, desempeñando un papel crítico en la transmisión de señales desde la membrana celular hasta el núcleo. La activación de Raf conduce a la fosforilación de MEK, que posteriormente activa ERK, influyendo en la división, diferenciación y supervivencia celular. Las mutaciones en Raf, particularmente en B-Raf, están asociadas con varios tipos de cáncer, lo que convierte a Raf en un objetivo crucial en la terapia contra el cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores y moduladores de Raf para apoyar su investigación en oncología, transducción de señales y desarrollo terapéutico.
Se han encontrado 86 productos para "Raf".
Filtrar por
Porcentaje de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Precio más bajo
- Precio más alto
- Pureza más baja
- Pureza más alta
- Entrega estimada más rápida
Anti-Phospho-RAF1 (Ser43) Antibody (8R108)
Anti-Phospho-RAF1 (Ser43) Antibody (8R108) is an antibody targeting Phospho-RAF1 (Ser43). Anti-Phospho-RAF1 (Ser43) Antibody (8R108) can be used in ELISA, IF.Forma y color:Odour LiquidAnti-Phospho-RAF1 (Ser259) Antibody (5X237)
Anti-Phospho-RAF1 (Ser259) Antibody (5X237) is an antibody targeting Phospho-RAF1 (Ser259). Anti-Phospho-RAF1 (Ser259) Antibody (5X237) can be used in ELISA, WB, IHC, IF.Forma y color:Odour LiquidRAS GTPase inhibitor 1 TFA
CAS:RAS GTPase inhibitor 1 TFA is a RAS GTPase inhibitor with potential antitumor activity.Fórmula:C27H28ClF4N5O2Pureza:98.43%Forma y color:SolidPeso molecular:565.99K-Ras(G12C) inhibitor 6
CAS:Irreversible K-Ras(G12C) inhibitor 6 fully modifies the protein at 10 μM after 24h in vitro.Fórmula:C17H22Cl2N2O3SPureza:89.07% - 97.09%Forma y color:SolidPeso molecular:405.33Kobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Fórmula:C14H9F4N5O4SPureza:98.36% - 99.39%Forma y color:SolidPeso molecular:419.311GW 5074
CAS:GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.Fórmula:C15H8Br2INO2Pureza:99.32%Forma y color:Yellow SolidPeso molecular:520.94Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Fórmula:C27H19ClFN5O3SPureza:98.27%Forma y color:Yellow SolidPeso molecular:547.988Ro 5126766
CAS:RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.Fórmula:C21H18FN5O5SPureza:98.3% - 98.81%Forma y color:White SolidPeso molecular:471.462PLX-4720
CAS:PLX-4720 is a potent and selective B-Raf (V600E) inhibitor designed to block the ATP-binding site of oncogenic B-Raf.Cost-effective and quality-assured.Fórmula:C17H14ClF2N3O3SPureza:97.78% - 99.96%Forma y color:White SolidPeso molecular:413.826AZ304
CAS:AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Fórmula:C27H25N5O2Pureza:99.82%Forma y color:SolidPeso molecular:451.5197Raf inhibitor 2
CAS:Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.Fórmula:C15H8Br2ClNO2Pureza:98.53%Forma y color:White SolidPeso molecular:429.491Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFórmula:C21H17ClF4N4O4Pureza:99.69%Forma y color:SolidPeso molecular:500.83PLX8394
CAS:Plixorafenib (PLX8394) is an orally active inhibitor of the serine/threonine protein kinase B-Raf (BRAF) protein.Cost-effective and quality-assured.Fórmula:C25H21F3N6O3SPureza:98.75% - >99.99%Forma y color:SolidPeso molecular:542.533Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Forma y color:SolidPeso molecular:482.815ZM 336372
CAS:ZM 336372 is a potent and selective c-Raf inhibitor.Fórmula:C23H23N3O3Pureza:97.24% - 97.51%Forma y color:SolidPeso molecular:389.45SB-590885
CAS:SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay).Fórmula:C27H27N5O2Pureza:95.42% - 99.06%Forma y color:SolidPeso molecular:453.5356K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Fórmula:C16H21ClIN3O4SPureza:97.33% - 97.45%Forma y color:SolidPeso molecular:513.778AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Fórmula:C22H19F4N7OPureza:99.49% - 99.75%Forma y color:SolidPeso molecular:473.4262BI-882370
CAS:BI-882370 is a specific RAF kinase inhibitor.Fórmula:C28H33F2N7O2SPureza:97.33% - 99.07%Forma y color:SolidPeso molecular:569.669RAF709
CAS:RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.Fórmula:C28H29F3N4O4Pureza:99.28% - 99.8%Forma y color:White SolidPeso molecular:542.5495
