Canal TRP / TRPV
Los canales TRP (Receptor Potencial Transitorio), incluida la subfamilia TRPV, son un grupo de canales iónicos involucrados en diversos procesos sensoriales, como la sensación de temperatura, la percepción del dolor y la osmorregulación. Los canales TRP están ampliamente expresados en diferentes tejidos y desempeñan un papel en las respuestas fisiológicas a estímulos ambientales. Los canales TRPV, en particular, están involucrados en la detección de cambios de temperatura y están implicados en condiciones como el dolor crónico, la inflamación y el cáncer. En CymitQuimica, ofrecemos una gama completa de moduladores de canales TRP/TRPV para apoyar su investigación en biología sensorial, manejo del dolor y transducción de señales.
Se han encontrado 99 productos para "Canal TRP / TRPV".
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FEMA-4809
CAS:FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.Fórmula:C17H17N3O2SPureza:99.9%Forma y color:SolidPeso molecular:327.4Ref: TM-T27308
1mg34,00€5mg73,00€1mL*10mM (DMSO)84,00€10mg110,00€25mg180,00€50mg255,00€100mg363,00€200mg497,00€ABT 102
CAS:ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.Fórmula:C21H24N4OPureza:98.38% - 99.86%Forma y color:White SolidPeso molecular:348.44Ref: TM-T29522
1mg109,00€5mg235,00€1mL*10mM (DMSO)245,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€Mavatrep
CAS:Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.Fórmula:C25H21F3N2OPureza:98.51% - 99.31%Forma y color:Yellow SolidPeso molecular:422.44Ref: TM-T16014
1mg63,00€2mg90,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg385,00€50mg618,00€100mg888,00€200mg1.243,00€Olvanil
CAS:Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Fórmula:C26H43NO3Pureza:99.58%Forma y color:SolidPeso molecular:417.62Ref: TM-T23106
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg75,00€25mg145,00€50mg236,00€100mg385,00€200mg560,00€Elismetrep
CAS:Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.Fórmula:C27H21F3N2O5SPureza:99.37% - 99.86%Forma y color:White SolidPeso molecular:542.53Ref: TM-T27253
1mg101,00€5mg241,00€1mL*10mM (DMSO)286,00€10mg385,00€25mg703,00€50mg888,00€100mg1.189,00€MSP3
CAS:MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Fórmula:C16H19NO3SPureza:99.89%Forma y color:SolidPeso molecular:305.39Pyr3
CAS:Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.Fórmula:C16H11Cl3F3N3O3Pureza:98.04%Forma y color:White SolidPeso molecular:456.63Ref: TM-T16687
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)81,00€10mg92,00€25mg203,00€50mg344,00€100mg485,00€200mg700,00€500mg1.063,00€PF-05105679
CAS:PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.Fórmula:C26H21FN2O3Pureza:99.84%Forma y color:SolidPeso molecular:428.45Ref: TM-T16483
1mg44,00€2mg57,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg138,00€25mg264,00€50mg404,00€100mg610,00€200mg848,00€GSK3395879
CAS:GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).Fórmula:C20H15F4N3O5SPureza:98%Forma y color:SolidPeso molecular:485.41A-1165442
CAS:A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.Fórmula:C22H20ClF2N3O2Forma y color:SolidPeso molecular:431.86JT010
CAS:JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).Fórmula:C16H19ClN2O3SPureza:99.75%Forma y color:Orange SolidPeso molecular:354.85MK-2295
CAS:MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.Fórmula:C27H31FN6O2Pureza:98.83% - 99.44%Forma y color:SolidPeso molecular:490.57Mesendogen
CAS:Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7Fórmula:C18H16ClF3N2OSPureza:99.66%Forma y color:SolidPeso molecular:400.85TRPV2-selective blocker 1
CAS:TRPV2-selective blocker 1 specifically inhibits TRPV2 channel activity in macrophages.Fórmula:C15H18OS2Pureza:99.96%Forma y color:Transparent LiquidPeso molecular:278.43Ref: TM-T80930
1mg105,00€1mL*10mM (DMSO)240,00€5mg250,00€10mg432,00€25mg858,00€50mg1.369,00€100mg1.783,00€AMG-0347
CAS:AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.Fórmula:C24H26F3N3O2Pureza:99.93%Forma y color:Yellow SolidPeso molecular:445.48Ref: TM-T29968
1mg215,00€5mg523,00€1mL*10mM (DMSO)537,00€10mg695,00€25mg1.054,00€50mg1.414,00€100mg1.900,00€200mg2.565,00€AMG2850
CAS:AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).Fórmula:C19H17F6N3OPureza:99.84%Forma y color:SolidPeso molecular:417.35Ref: TM-T10300
1mg71,00€5mg161,00€1mL*10mM (DMSO)172,00€10mg235,00€25mg423,00€50mg627,00€100mg803,00€TRPA1 Antagonist 1
CAS:TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.Fórmula:C24H20F6N5Na2O7PSPureza:98%Forma y color:SolidPeso molecular:713.45ELP-004
CAS:ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.Fórmula:C10H11Cl2NOForma y color:SolidPeso molecular:232.106IAA65
CAS:IAA65 is a potent selective TRPA1 inhibitor; IC50 4.3 nM; blocks calcium influx; analgesic; used for inflammatory and neuropathic pain research.Fórmula:C16H13F6NO2Pureza:97.46%Forma y color:SolidPeso molecular:365.27
