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Canal de potasio

Canal de potasio

Los canales de potasio son un grupo diverso de proteínas de membrana que facilitan el flujo de iones de potasio (K+) a través de la membrana celular. Estos canales desempeñan un papel crucial en el mantenimiento del potencial de membrana en reposo, la regulación del volumen celular y el control de la excitabilidad de las neuronas y las células musculares. Los canales de potasio están involucrados en varios procesos fisiológicos, incluyendo la regulación del ritmo cardíaco, la secreción de insulina y la liberación de neurotransmisores. La disfunción de los canales de potasio está relacionada con condiciones como arritmias, epilepsia e hipertensión. En CymitQuimica, ofrecemos una amplia gama de moduladores de canales de potasio para apoyar su investigación en electrofisiología, salud cardiovascular y neurobiología.

Se han encontrado 276 productos de "Canal de potasio"

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  • Ropivacaine hydrochloride monohydrate

    CAS:
    <p>Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.</p>
    Fórmula:C17H29ClN2O2
    Pureza:99.94% - 99.95%
    Forma y color:White Solid
    Peso molecular:328.88
  • Cholesterol myristate

    CAS:
    <p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>
    Fórmula:C41H72O2
    Pureza:99.65%
    Forma y color:Solid
    Peso molecular:597.01
  • Quinidine sulfate dihydrate

    CAS:
    <p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>
    Fórmula:C40H54N4O10S
    Pureza:99.85%
    Forma y color:White To Light Yellow Crystal Powde
    Peso molecular:782.9
  • ML277

    CAS:
    <p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>
    Fórmula:C23H25N3O4S2
    Pureza:99.35%
    Forma y color:Solid
    Peso molecular:471.59
  • APD668

    CAS:
    <p>APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.</p>
    Fórmula:C21H24FN5O5S
    Pureza:99.74% - 99.97%
    Forma y color:Solid
    Peso molecular:477.51
  • Amifampridine

    CAS:
    <p>Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.</p>
    Fórmula:C5H7N3
    Pureza:99.82%
    Forma y color:Slightly Beige Powder
    Peso molecular:109.13
  • TKIM

    CAS:
    <p>TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.</p>
    Fórmula:C18H14ClN3O2S
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:371.84
  • ICA-069673

    CAS:
    <p>ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).</p>
    Fórmula:C11H6ClF2N3O
    Pureza:99.04% - 99.68%
    Forma y color:Solid
    Peso molecular:269.63
  • NS309

    CAS:
    <p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>
    Fórmula:C8H4Cl2N2O2
    Pureza:97.55%
    Forma y color:Solid
    Peso molecular:231.04
  • BAPTA-AM

    CAS:
    <p>BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).</p>
    Fórmula:C34H40N2O18
    Pureza:98% - 99.47%
    Forma y color:White Powder Or Crystalline Powder
    Peso molecular:764.68
  • Quinidine

    CAS:
    <p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>
    Fórmula:C20H24N2O2
    Pureza:97.03% - 99.99%
    Forma y color:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)
    Peso molecular:324.42
  • Talatisamine

    CAS:
    <p>Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.</p>
    Fórmula:C24H39NO5
    Pureza:98.62% - 99.44%
    Forma y color:Solid
    Peso molecular:421.57
  • VU0134992

    CAS:
    <p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>
    Fórmula:C20H31BrN2O2
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:411.38
  • Endoxifen (Z-isomer)

    CAS:
    <p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>
    Fórmula:C25H27NO2
    Pureza:99.19% - 99.81%
    Forma y color:Solid
    Peso molecular:373.49
  • Paederosidic acid methyl ester

    CAS:
    <p>Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.</p>
    Fórmula:C19H26O12S
    Pureza:99.67% - 99.91%
    Forma y color:Solid
    Peso molecular:478.47
  • 20(S)-Ginsenoside Rg3

    CAS:
    <p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>
    Fórmula:C42H72O13
    Pureza:98.11% - 99.93%
    Forma y color:Solid
    Peso molecular:785.01
  • KCNQ2/3 activator-1

    CAS:
    <p>KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.</p>
    Fórmula:C23H29FN2O
    Pureza:99.16% - 99.47%
    Forma y color:Solid
    Peso molecular:368.49
  • 2,2,2-Trichloroethanol

    CAS:
    <p>2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.</p>
    Fórmula:C2H3Cl3O
    Pureza:99.74%
    Forma y color:Liquid
    Peso molecular:149.4
  • Yoda 1

    CAS:
    <p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>
    Fórmula:C13H8Cl2N4S2
    Pureza:98% - 99.98%
    Forma y color:Solid
    Peso molecular:355.27
  • Quinine hydrochloride dihydrate

    CAS:
    <p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>
    Fórmula:C20H24N2O2·HCl·2H2O
    Pureza:99.91%
    Forma y color:White To Light Yellow Crystal Powder
    Peso molecular:396.91