Canal de cloruro
Los canales de cloruro son proteínas de membrana que controlan el movimiento de los iones de cloruro a través de las membranas celulares, desempeñando un papel vital en el mantenimiento del volumen celular, la excitabilidad eléctrica y el equilibrio ácido-base. La desregulación de los canales de cloruro está relacionada con enfermedades como la fibrosis quística, la epilepsia y los trastornos renales. En CymitQuimica, ofrecemos una variedad de moduladores de canales de cloruro para apoyar su investigación en el transporte de iones, la homeostasis celular y los mecanismos de enfermedades.
Se han encontrado 53 productos de "Canal de cloruro"
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Fenamic acid
CAS:Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats.Fórmula:C13H11NO2Pureza:99.6%Forma y color:White To Off-White Crystalline PowderPeso molecular:213.2319CaCCinh-A01
CAS:CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).Fórmula:C18H21NO4SPureza:99.36% - >99.99%Forma y color:SolidPeso molecular:347.43Talniflumate
CAS:<p>Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell</p>Fórmula:C21H13F3N2O4Pureza:98% - 99.81%Forma y color:White To Pale Yellow Crystalline PowderPeso molecular:414.33MONNA
CAS:MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.Fórmula:C18H14N2O5Pureza:98.29%Forma y color:SolidPeso molecular:338.31Lubiprostone
CAS:Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Forma y color:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46Guanidinoethyl sulfonate
CAS:Guanidinoethyl sulfonate (Taurocyamine) is a competitive glycine receptor antagonist.Fórmula:C3H9N3O3SPureza:99.43% - 99.47%Forma y color:SolidPeso molecular:167.19Adjudin
CAS:Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Fórmula:C15H12Cl2N4OPureza:96.51% - ≥95%Forma y color:SolidPeso molecular:335.19NPPB
CAS:NPPB is a chloride channel blocker with IC50 of 80 nM .Fórmula:C16H16N2O4Pureza:99.95%Forma y color:Light Yellow To Yellow SolidPeso molecular:300.31Anthracene-9-carboxylic acid
CAS:Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.Fórmula:C15H10O2Pureza:99.05%Forma y color:Yellow Cystalline PowderPeso molecular:222.24Org 25543
CAS:Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.Fórmula:C24H32N2O4Pureza:99.13%Forma y color:SolidPeso molecular:412.52Phenyl benzoate
CAS:Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.Fórmula:C13H10O2Pureza:99.63%Forma y color:White Crystalline PowderPeso molecular:198.22Selamectin
CAS:Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening inFórmula:C43H63NO11Pureza:99.84%Forma y color:SolidPeso molecular:769.96Hydroflumethiazide
CAS:Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.Fórmula:C8H8F3N3O4S2Forma y color:Crystals SolidPeso molecular:331.29Alilusem
CAS:Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.Fórmula:C17H15ClKN2O5SForma y color:SolidPeso molecular:433.92H100
CAS:H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.Fórmula:C18H16N2O6SPureza:98%Forma y color:SolidPeso molecular:388.4NS5818
CAS:NS5818 inhibits ClC.Fórmula:C23H19Cl2N7O2Pureza:98%Forma y color:SolidPeso molecular:496.35ANO1-IN-2
CAS:ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.Fórmula:C16H14ClN3O2S2Forma y color:SolidPeso molecular:379.88BTG-1640
CAS:BTG-1640 is used potentially for the treatment of anxiety and panic disorder.Fórmula:C15H19NO2Forma y color:SolidPeso molecular:245.32Bts 39542
CAS:Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.Fórmula:C16H11ClN4O3SForma y color:SolidPeso molecular:374.8IAA-94
CAS:IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.Fórmula:C17H18Cl2O4Forma y color:SolidPeso molecular:357.23
