Receptor CGRP
Los receptores de CGRP están involucrados en la transmisión del dolor y la regulación del flujo sanguíneo. El CGRP es un neuropéptido que desempeña un papel crucial en la fisiopatología de la migraña al dilatar los vasos sanguíneos y modular las vías de señalización del dolor. Dirigirse a los receptores de CGRP se ha convertido en un enfoque prometedor en el desarrollo de terapias para la migraña. En CymitQuimica, ofrecemos una gama de moduladores de receptores de CGRP para apoyar su investigación en el manejo del dolor, neurobiología y salud vascular.
Se han encontrado 55 productos de "Receptor CGRP"
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CGRP 8-37 (rat)
CAS:CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.Fórmula:C138H224N42O41Pureza:99.28%Forma y color:SolidPeso molecular:3127.51Adrenomedullin (AM) (22-52), human acetate
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and anFórmula:C161H256N46O50Pureza:99.42%Forma y color:SolidPeso molecular:3636.09α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFórmula:C162H262N50O52S2·C2HF3O2Pureza:98%Forma y color:SolidGalcanezumab
CAS:Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.Pureza:> 95%Forma y color:LiquidPeso molecular:144.08 kDaUbrogepant-d5
Ubrogepant-d5 (MK-1602-d5) is the deuterium-labeled version of Ubrogepant. It is an orally active and selective antagonist of the calcitonin gene-related peptide receptor (CGRP). Ubrogepant exhibits high affinity for CGRP receptors in humans and rhesus monkeys, effectively blocking the cAMP response induced by α-CGRP stimulation. This compound is utilized in studies focused on acute migraine.Forma y color:Odour Solidα-CGRP (mouse, rat) (TFA)
α-CGRP (mouse, rat) TFA is a neuropeptide (calcitonin gene-related peptide) predominantly found at neuromuscular junctions and acts as a potent vasodilator. This compound is useful in research concerning cardiovascular, pro-inflammatory, migraine, and metabolic processes.Forma y color:Odour SolidCGRP antagonist 6
CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.Forma y color:Odour SolidAdrenomedullin (1-50), rat
CAS:Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.Fórmula:C248H381N77O75S5Pureza:98%Forma y color:SolidPeso molecular:5729.5Adrenomedullin (AM) (22-52), human
CAS:Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.Fórmula:C159H252N46O48Pureza:98%Forma y color:SolidPeso molecular:3576.04HCGRP-(8-37)
CAS:Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFórmula:C139H230N44O38Pureza:98%Forma y color:SolidPeso molecular:3125.59Calcitonin (human)
CAS:Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.Fórmula:C151H226N40O45S3Pureza:98%Forma y color:White Lyophilized PowderPeso molecular:3417.87α-CGRP, rat
CAS:Endogenous neuropeptide, potent vasodilatorFórmula:C162H262N50O52S2Pureza:98%Forma y color:SolidPeso molecular:3806.25Telcagepant
CAS:Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.Fórmula:C26H27F5N6O3Pureza:98.98% - 98.98%Forma y color:SolidPeso molecular:566.52SUN B8155
CAS:SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Fórmula:C14H15N3O3Pureza:99.38% - 99.99%Forma y color:SolidPeso molecular:273.29Calcitonin (salmon)
CAS:Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.Fórmula:C145H240N44O48S2Pureza:99.41% - 99.80%Forma y color:PowderPeso molecular:3431.85Olcegepant
CAS:Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4Fórmula:C38H47Br2N9O5Pureza:96.08% - 97.24%Forma y color:SolidPeso molecular:869.65Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Fórmula:C36H47ClN8O3Pureza:98.93%Forma y color:SolidPeso molecular:675.3Ref: TM-T8682
1mg102,00€5mg215,00€1mL*10mM (DMSO)313,00€10mg316,00€25mg535,00€50mg763,00€100mg1.054,00€Calcitonin(salmon) Acetate(47931-85-1(free base))
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5Fórmula:C145H240N44O48S2Pureza:99.29%Forma y color:SolidPeso molecular:3431.85BCTC
CAS:BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)Fórmula:C20H25ClN4OPureza:99.21%Forma y color:SolidPeso molecular:372.89HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.Fórmula:C141H234N44O40Pureza:99.29%Forma y color:SolidPeso molecular:3185.64
