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Receptor CGRP

Receptor CGRP

Los receptores de CGRP están involucrados en la transmisión del dolor y la regulación del flujo sanguíneo. El CGRP es un neuropéptido que desempeña un papel crucial en la fisiopatología de la migraña al dilatar los vasos sanguíneos y modular las vías de señalización del dolor. Dirigirse a los receptores de CGRP se ha convertido en un enfoque prometedor en el desarrollo de terapias para la migraña. En CymitQuimica, ofrecemos una gama de moduladores de receptores de CGRP para apoyar su investigación en el manejo del dolor, neurobiología y salud vascular.

Se han encontrado 51 productos de "Receptor CGRP"

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  • Adrenomedullin (AM) (22-52), human acetate


    <p>Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an</p>
    Fórmula:C161H256N46O50
    Pureza:99.42%
    Forma y color:Solid
    Peso molecular:3636.09
  • α-CGRP (mouse, rat) TFA


    <p>α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and</p>
    Fórmula:C162H262N50O52S2·C2HF3O2
    Pureza:98%
    Forma y color:Solid
  • Calcitonin-13C6,15N4 TFA


    <p>Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.</p>
    Fórmula:C1401C5H240N4315NO48S2·5C2HF3O2
    Forma y color:Solid
    Peso molecular:4007.93
  • Galcanezumab

    CAS:
    <p>Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.</p>
    Pureza:> 95%
    Forma y color:Liquid
    Peso molecular:144.08 kDa
  • CGRP antagonist 6


    <p>CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.</p>
    Forma y color:Odour Solid
  • Adrenomedullin (1-50), rat

    CAS:
    <p>Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.</p>
    Fórmula:C248H381N77O75S5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:5729.5
  • Adrenomedullin (AM) (22-52), human

    CAS:
    <p>Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.</p>
    Fórmula:C159H252N46O48
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3576.04
  • HCGRP-(8-37)

    CAS:
    <p>Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist</p>
    Fórmula:C139H230N44O38
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3125.59
  • Calcitonin (human)

    CAS:
    <p>Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.</p>
    Fórmula:C151H226N40O45S3
    Pureza:98%
    Forma y color:White Lyophilized Powder
    Peso molecular:3417.87
  • α-CGRP, rat

    CAS:
    <p>Endogenous neuropeptide, potent vasodilator</p>
    Fórmula:C162H262N50O52S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3806.25
  • β-CGRP, human

    CAS:
    <p>β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular</p>
    Fórmula:C162H267N51O48S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3793.41
  • SUN B8155

    CAS:
    <p>SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.</p>
    Fórmula:C14H15N3O3
    Pureza:99.38% - 99.38%
    Forma y color:Solid
    Peso molecular:273.29
  • Telcagepant

    CAS:
    <p>Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.</p>
    Fórmula:C26H27F5N6O3
    Pureza:98.98% - 98.98%
    Forma y color:Solid
    Peso molecular:566.52
  • Calcitonin (salmon)

    CAS:
    <p>Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.</p>
    Fórmula:C145H240N44O48S2
    Pureza:99.41% - 99.80%
    Forma y color:Powder
    Peso molecular:3431.85
  • Rimegepant

    CAS:
    <p>View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.</p>
    Fórmula:C28H28F2N6O3
    Pureza:99.1% - 99.99%
    Forma y color:Solid
    Peso molecular:534.56
  • BCTC

    CAS:
    <p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>
    Fórmula:C20H25ClN4O
    Pureza:99.21%
    Forma y color:Solid
    Peso molecular:372.89
  • Calcitonin(salmon) Acetate(47931-85-1(free base))


    <p>Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5</p>
    Fórmula:C145H240N44O48S2
    Pureza:99.29%
    Forma y color:Solid
    Peso molecular:3431.85
  • Olcegepant

    CAS:
    <p>Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4</p>
    Fórmula:C38H47Br2N9O5
    Pureza:96.08% - 97.24%
    Forma y color:Solid
    Peso molecular:869.65
  • HCGRP-(8-37) acetate


    <p>HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.</p>
    Fórmula:C141H234N44O40
    Pureza:99.29%
    Forma y color:Solid
    Peso molecular:3185.64
  • Vazegepant hydrochloride

    CAS:
    <p>Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.</p>
    Fórmula:C36H47ClN8O3
    Pureza:98.93%
    Forma y color:Solid
    Peso molecular:675.3