Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Se han encontrado 258 productos de "Canal de sodio"
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Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Fórmula:C21H29N3OPureza:99.62%Forma y color:SolidPeso molecular:339.47LTGO-33
CAS:LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.
Fórmula:C21H17F4N3O3SPureza:97.6%Forma y color:SoildPeso molecular:467.44ATX-II
CAS:ATX-II, an Na+ channel modulator toxin derived from the sea anemone (Anemonia sulcata), causes delayed inactivation of the Na+ channels and has been linked toFórmula:C213H323N63O61S6Pureza:98%Forma y color:SolidPeso molecular:4934.62Veratridine
CAS:Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.Fórmula:C36H51NO11Pureza:98.07% - 99.27%Forma y color:Yellowish-White Amorphous Powder PowderPeso molecular:673.79Tap1a
Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301Fórmula:C174H258N52O55S7Pureza:98%Forma y color:SolidPeso molecular:4182.68π-TRTX-Hm3a
π-TRTX-Hm3a, a 37-amino acid peptide derived from the venom of the Togo starburst tarantula (Heteroscodra maculata), selectively inhibits the acid-sensing ionFórmula:C186H290N56O49S6Pureza:98%Forma y color:SolidPeso molecular:4287.03ω-Conotoxin CVIB
CAS:ω-Conotoxin CVIB is an antagonist of non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs).Fórmula:C102H173N41O32S7Pureza:98%Forma y color:SolidPeso molecular:2710.18BmK-M1
BmK-M1, a scorpion-derived toxin, consists of a 64-amino acid polypeptide stabilized by four disulfide bridges.Fórmula:C313H467N91O91S8Pureza:98%Forma y color:SolidPeso molecular:7217.13Huwentoxin-IV
CAS:Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.Fórmula:C174H278N52O51S6Pureza:98%Forma y color:SolidPeso molecular:4106.79Dc1a
Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).Fórmula:C276H414N76O84S8Pureza:98%Forma y color:SolidPeso molecular:6397.22Halazone
CAS:Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.Fórmula:C7H5Cl2NO4SPureza:98.64%Forma y color:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Peso molecular:270.09SLC26A3-IN-2
CAS:Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.Fórmula:C19H13ClN2O2SPureza:99.86%Forma y color:SolidPeso molecular:368.84OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.Fórmula:C308H466N90O95S8Pureza:98%Forma y color:SolidPeso molecular:7206.1Pterinotoxin-1
Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].Fórmula:C163H251N49O53S7Pureza:98%Forma y color:SolidPeso molecular:3969.49Lifarizine FA
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.Fórmula:C30H34N4O2Pureza:99.55%Forma y color:SolidPeso molecular:482.62GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.Forma y color:Odour SolidBenzonatate (PEGn)
CAS:Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.Fórmula:(C2H4O)nC12H17NO2Forma y color:Solidµ-Conotoxin-CnIIIC acetate
µ-Conotoxin-CnIIIC acetate is a NaV1.4 sodium channel antagonist, a conotoxin peptide consisting of 22 amino acids, used for muscle relaxation and pain relief.Fórmula:C92H139N35O28S6·xC2H4O2Pureza:99.94%Forma y color:SolidPeso molecular:2375.70 (free base)Hm1a
Hm1a, a disulfide-rich spider-venom peptide and NaV1.1 activator, reestablishes the function of inhibitory interneurons in a Dravet syndrome (DS) mouse model [1Fórmula:C170H239N47O54S6Pureza:98%Forma y color:SolidPeso molecular:3997.39Solpecainol
CAS:solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.Fórmula:C18H23NO3Pureza:99.71%Forma y color:SoildPeso molecular:301.38
