Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Se han encontrado 202 productos de "Canal de sodio"
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APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Fórmula:C196H280N54O61S6Pureza:98%Forma y color:SolidPeso molecular:4561.06Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Fórmula:C272H429N85O84S10Pureza:98%Forma y color:SolidPeso molecular:6554.51Analgesic agent-2
<p>Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human</p>Fórmula:C21H21ClF2N4O2Pureza:98%Forma y color:SolidPeso molecular:434.87ProTx II
CAS:<p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>Fórmula:C168H250N46O41S8Pureza:98%Forma y color:SolidPeso molecular:3826.59PF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Fórmula:C35H35Cl3F3N7O3S2Pureza:99.16%Forma y color:SolidPeso molecular:829.18Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Forma y color:Odour SolidHuwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Fórmula:C174H278N52O51S6Pureza:98%Forma y color:SolidPeso molecular:4106.79OD1
<p>Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.</p>Fórmula:C308H466N90O95S8Pureza:98%Forma y color:SolidPeso molecular:7206.1Phrixotoxin 3
CAS:<p>Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.</p>Fórmula:C176H269N51O48S6Pureza:98%Forma y color:SolidPeso molecular:4059.74Zandatrigine
CAS:<p>Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy</p>Fórmula:C22H25FN4O2S2Pureza:99.98%Forma y color:SolidPeso molecular:460.59Benzonatate (PEGn)
CAS:<p>Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.</p>Fórmula:(C2H4O)nC12H17NO2Forma y color:SolidSodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Forma y color:Odour SolidLifarizine FA
<p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>Fórmula:C30H34N4O2Pureza:99.55%Forma y color:SolidPeso molecular:482.62GX 201
CAS:<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Fórmula:C25H27ClF4N2O4SPureza:99.81%Forma y color:SolidPeso molecular:563Solpecainol
CAS:<p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>Fórmula:C18H23NO3Pureza:99.71%Forma y color:SoildPeso molecular:301.38Mepivacaine hydrochloride
CAS:<p>Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.</p>Fórmula:C15H22N2O·HClPureza:98.76% - 99.94%Forma y color:White Or Off White Crystalline PowderPeso molecular:282.81Nav1.7-IN-18
<p>Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, demonstrating analgesic effects in transgenic mice with inherited erythromelalgia (IEM).</p>Fórmula:C30H33Cl2F2NO4Forma y color:SolidPeso molecular:580.49ProTx II TFA
<p>ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over</p>Fórmula:C168H250N46O41S8·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:3826.59 (free base)Mexiletine-d6 hydrochloride
CAS:<p>Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.</p>Fórmula:C11H18ClNOPureza:98%Forma y color:SolidPeso molecular:221.76AM-2099
CAS:<p>AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.</p>Fórmula:C19H13F3N4O3S2Forma y color:SolidPeso molecular:466.46
