Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Se han encontrado 202 productos de "Canal de sodio"
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Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Fórmula:C8H5F3N2OSPureza:99.71% - 99.88%Forma y color:PowderPeso molecular:234.2Benzocaine N-Glucoside (a/b mixture)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.<br>References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);<br></p>Fórmula:C15H21NO7Forma y color:NeatPeso molecular:327.33Propoxycaine hydrochloride
CAS:<p>Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.</p>Fórmula:C16H27ClN2O3Pureza:97.25%Forma y color:SolidPeso molecular:330.85Eleclazine
CAS:<p>Eleclazine (GS-6615) is a novel and selective voltage-gated sodium channel inhibitor with antiarrhythmic properties that reduces peak sodium current (INaP).</p>Fórmula:C21H16F3N3O3Pureza:98.67%Forma y color:SolidPeso molecular:415.37Deacetamide Acetonitrile-pentisomide
CAS:Producto controlado<p>Applications Deacetamide Acetonitrile-pentisomide is an intermediate in the synthesis of Pentisomide (P275600). Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).<br>References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992); Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)<br></p>Fórmula:C19H31N3Forma y color:NeatPeso molecular:301.47N-(Chloroacetyl)-2,5-dimethylaniline
CAS:Producto controlado<p>Applications N-(Chloroacetyl)-2,5-dimethylaniline is an intermediate in the synthesis of impurities of Lidocaine (L397800), an anesthetic local agent and antiarrythmic class IB agent.<br>References Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),<br></p>Fórmula:C10H12ClNOForma y color:NeatPeso molecular:197.663-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
CAS:Producto controlado<p>Applications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.<br>References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)<br></p>Fórmula:C10H12ClNO3SForma y color:NeatPeso molecular:261.73Methocarbamol D5
CAS:<p>Methocarbamol is a central muscle relaxant. Methocarbamol D5 is deuterium labeled Methocarbamol.</p>Fórmula:C11H15NO5Pureza:98%Forma y color:SolidPeso molecular:246.27Propafenone D7 hydrochloride
CAS:<p>Propafenone D7 hydrochloride is the deuterium labeled Propafenone, and is a classic anti-arrhythmic medication.</p>Fórmula:C21H28ClNO3Pureza:98%Forma y color:SolidPeso molecular:384.953-Deoxyyunaconitine
CAS:Producto controlado<p>Applications 3-Deoxyyunaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes.<br>References Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),<br></p>Fórmula:C35H49NO10Forma y color:NeatPeso molecular:643.761,2,4-Oxadiazol-3-amine
CAS:Producto controlado<p>Applications 1,2,4-oxadiazol-3-amine (cas# 39512-64-6) is a useful research chemical.<br></p>Fórmula:C2H3N3OForma y color:NeatPeso molecular:85.066-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)hexanamide
Producto controlado<p>Applications 6-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)-hexanamide is a derivative of Bupivacaine (B689560), a sodium channel blocker, local anesthetic.<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Fórmula:C17H28N2O2Forma y color:NeatPeso molecular:292.416Halofuginone
CAS:<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Fórmula:C16H17BrClN3O3Pureza:99.53%Forma y color:Off-White SolidPeso molecular:414.68Clopamide
CAS:<p>Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.</p>Fórmula:C14H20ClN3O3SPureza:99.71%Forma y color:White To Yellowish Crystalline PowderPeso molecular:345.84Nav1.7 inhibitor
CAS:<p>Nav1.7 inhibitor is a Nav1.7 inhibitor for research in the field of pain and anesthesia.</p>Fórmula:C15H11Cl3FNO4SPureza:97.52%Forma y color:SolidPeso molecular:426.68GX-585
CAS:<p>GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.</p>Fórmula:C24H25Cl2FN4O3SPureza:99.02% - 99.03%Forma y color:SolidPeso molecular:539.45(5R)-BW-4030W92
CAS:<p>(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer.</p>Fórmula:C11H9Cl2FN4Pureza:98.27%Forma y color:SolidPeso molecular:287.12Sodium Channel inhibitor 2
CAS:<p>Sodium Channel inhibitor 2 is a blocker of sodium channel.</p>Fórmula:C26H25Cl2N3OPureza:98%Forma y color:SolidPeso molecular:466.4GNE-0439
CAS:<p>GNE-0439 is a Nav1.7-selective inhibitor (IC50 0.34 μM), also targeting Nav1.5 and mutant N1742K channels, valuable for ion channel research.</p>Fórmula:C21H31NO3Pureza:99.60%Forma y color:SolidPeso molecular:345.48
