Canal de sodio
Se han encontrado 258 productos de "Canal de sodio"
6-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)hexanamide
Producto controladoApplications 6-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)-hexanamide is a derivative of Bupivacaine (B689560), a sodium channel blocker, local anesthetic.
References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),Fórmula:C17H28N2O2Forma y color:NeatPeso molecular:292.4163-Hydroxy-4-phenylbenzoic Acid
CAS:Producto controladoApplications 3-Hydroxy-4-phenylbenzoic Acid is a useful reagent for the preparation of spiro[3,4-dihydro-2H-pyrrolo[1,2-a]pyrazine-1,4'-piperidine] derivatives as modulators of sodium ion channel.
References Hadida Ruah, S. S., et al.: U.S. Pat. Appl. Publ. (2012), US 20120196869 A1Fórmula:C13H10O3Forma y color:NeatPeso molecular:214.221,2,4-Oxadiazol-3-amine
CAS:Producto controladoApplications 1,2,4-oxadiazol-3-amine (cas# 39512-64-6) is a useful research chemical.
Fórmula:C2H3N3OForma y color:NeatPeso molecular:85.06Pentisomide
CAS:Producto controladoApplications Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).
References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992), Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)Fórmula:C19H33N3OForma y color:NeatPeso molecular:319.483-Deoxyyunaconitine
CAS:Producto controladoApplications 3-Deoxyyunaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes.
References Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),Fórmula:C35H49NO10Forma y color:NeatPeso molecular:643.76Clopamide
CAS:Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.Fórmula:C14H20ClN3O3SPureza:99.71%Forma y color:White To Yellowish Crystalline PowderPeso molecular:345.84Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Fórmula:C16H17BrClN3O3Pureza:99.53%Forma y color:Off-White SolidPeso molecular:414.68Ref: TM-T6856
1mg34,00€5mg82,00€10mg116,00€25mg227,00€50mg344,00€100mg517,00€500mg1.134,00€1mL*10mM (DMSO)92,00€DPI 201-106
CAS:DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.Fórmula:C29H30N4O2Pureza:99.94%Forma y color:SolidPeso molecular:466.57Phenamil
CAS:Phenamil is an inhibitor of epithelial sodium channels, activates the osteomorphin protein pathway to promote bone repair and induces significant fat formation.Fórmula:C12H12ClN7OPureza:99.07%Forma y color:SolidPeso molecular:305.72(5R)-BW-4030W92
CAS:(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer.Fórmula:C11H9Cl2FN4Pureza:98.27%Forma y color:SolidPeso molecular:287.12NHE3-IN-2
CAS:NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.Fórmula:C15H12ClN5Forma y color:SolidPeso molecular:297.74PF 05089771 tosylate
CAS:PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.Fórmula:C18H12Cl2FN5O3S2·C7H8O3SPureza:98.55%Forma y color:SolidPeso molecular:672.56GNE-0439
CAS:GNE-0439 is a Nav1.7-selective inhibitor (IC50 0.34 μM), also targeting Nav1.5 and mutant N1742K channels, valuable for ion channel research.Fórmula:C21H31NO3Pureza:99.60%Forma y color:SolidPeso molecular:345.48Ref: TM-T11437
1mg154,00€5mg371,00€10mg620,00€25mg1.305,00€50mg1.783,00€100mg2.250,00€1mL*10mM (DMSO)409,00€Sodium Channel inhibitor 2
CAS:Sodium Channel inhibitor 2 is a blocker of sodium channel.Fórmula:C26H25Cl2N3OPureza:98%Forma y color:SolidPeso molecular:466.4E 0747
CAS:E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.
Fórmula:C21H28ClN3O4Pureza:95.17%Forma y color:SolidPeso molecular:421.92GX-674
CAS:GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study ofFórmula:C21H13ClF2N6O3S2Pureza:98.60%Forma y color:SolidPeso molecular:534.95Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Forma y color:SolidPeso molecular:495.59Ref: TM-T3524
1mg34,00€2mg49,00€5mg74,00€10mg106,00€25mg207,00€50mg310,00€100mg469,00€500mg897,00€1mL*10mM (DMSO)84,00€GX-585
CAS:GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.Fórmula:C24H25Cl2FN4O3SPureza:99.02% - 99.03%Forma y color:SolidPeso molecular:539.45GDC-0276
CAS:GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.Fórmula:C24H31FN2O4SPureza:99.77%Forma y color:SolidPeso molecular:462.58
