Canal de calcio
Los canales de calcio son proteínas de membrana que regulan el flujo de iones de calcio hacia dentro y fuera de las células, lo cual es esencial para diversas funciones celulares, como la contracción muscular, la liberación de neurotransmisores y la expresión génica. La desregulación de la actividad de los canales de calcio está asociada con condiciones como la hipertensión, las arritmias cardíacas y los trastornos neurológicos. En CymitQuimica, ofrecemos una amplia selección de moduladores de canales de calcio para apoyar su investigación en salud cardiovascular, neurobiología y transducción de señales.
Se han encontrado 493 productos de "Canal de calcio"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BX430
CAS:<p>BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist</p>Fórmula:C15H15Br2N3OPureza:97.34%Forma y color:SolidPeso molecular:413.11Trimethadione
CAS:<p>Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.</p>Fórmula:C6H9NO3Pureza:99.67% - >99.99%Forma y color:SolidPeso molecular:143.145,5-Dimethyloxazolidine-2,4-dione
CAS:<p>5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE.</p>Fórmula:C5H7NO3Pureza:99.12%Forma y color:Drypowder PelletslargecrystalsPeso molecular:129.11GSK-7975A
CAS:<p>GSK-7975A is a potent and orally available inhibitor of CRAC channel.</p>Fórmula:C18H12F5N3O2Pureza:98.92%Forma y color:SolidPeso molecular:397.3Bupivacaine hydrochloride
CAS:<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Fórmula:C18H28N2O·HClPureza:99.9% - >99.99%Forma y color:SolidPeso molecular:324.89Praziquantel
CAS:<p>Praziquantel (Droncit) is an anthelmintic that paralyzes worms by increasing calcium in muscle cells, causing tegument damage and immune response.</p>Fórmula:C19H24N2O2Pureza:99.67% - 99.69%Forma y color:SolidPeso molecular:312.41Ca2+ channel agonist 1
CAS:<p>Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.</p>Fórmula:C19H26N6OPureza:97.71%Forma y color:SolidPeso molecular:354.45Caloxin 2A1 TFA
<p>Caloxin 2A1 TFA is a PM Ca2+ pump inhibitor that inhibits human red blood cell Ca2+-Mg2+-ATPase leakage.</p>Fórmula:C66H92F3N19O24Pureza:99.89%Forma y color:SolidPeso molecular:1592.55Strontium ranelate
CAS:<p>Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.</p>Fórmula:C12H6N2O8S·2SrPureza:98.97%Forma y color:Crystalline SolidPeso molecular:513.49GV-58
CAS:<p>GV-58 agonizes N/P-Q-type Ca2+ channels (EC50: 7.21/8.81 μM) with 20x less inhibition on CDK kinases.</p>Fórmula:C18H26N6OSPureza:97.36%Forma y color:SolidPeso molecular:374.5Penfluridol
CAS:<p>Penfluridol (TLP-607) is a highly potent antipsychotic.</p>Fórmula:C28H27ClF5NOPureza:98.9% - 99.87%Forma y color:Off-White To White Crystalline PowderPeso molecular:523.97Catharanthine tartrate
CAS:<p>Catharanthine tartrate (Catharanthine hemitartrate) is an alkaloid from periwinkle that inhibits voltage-gated L-type calcium channels and has antitumor effect.</p>Fórmula:C25H30N2O8Pureza:99.91%Forma y color:SolidPeso molecular:486.51PACAP-38 (31-38), human, mouse, rat
CAS:<p>PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production</p>Fórmula:C47H83N17O11Pureza:98%Forma y color:SolidPeso molecular:1062.27D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Fórmula:C6H12Na2O12P2Forma y color:SolidPeso molecular:384.08PACAP-38 (31-38), human, mouse, rat TFA
<p>PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.</p>Fórmula:C49H84F3N17O13Pureza:98%Forma y color:SolidPeso molecular:1176.29Nesiritide
CAS:<p>Nesiritide, recombinant human B-type natriuretic peptide, binds NPR-A/C with Kd 7.3/13 pM.</p>Fórmula:C143H244N50O42S4Pureza:98%Forma y color:SolidPeso molecular:3464.04NAADP tetrasodium salt
CAS:<p>Ca2+ mobilizing agent</p>Fórmula:C21H27N6O18P3Pureza:98%Forma y color:SolidPeso molecular:744.39NSC156529
CAS:<p>NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.</p>Fórmula:C28H21ClS2Pureza:98%Forma y color:SolidPeso molecular:457.05D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:<p>Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.</p>Fórmula:C6H8Na8O18P4Forma y color:SolidPeso molecular:675.93Triphenylethylene
CAS:<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C20H16Forma y color:White PowderPeso molecular:256.34G-Glu-Ser
CAS:<p>G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.</p>Fórmula:C8H14N2O6Forma y color:SolidPeso molecular:234.21Ryanodine
CAS:<p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>Fórmula:C25H35NO9Pureza:98%Forma y color:White SolidPeso molecular:493.553BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Fórmula:C34H28N4O4Pureza:98.34%Forma y color:SolidPeso molecular:556.61ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Fórmula:C106H178N40O32S7Pureza:98%Forma y color:White Lyophilised SolidPeso molecular:2749Ziconotide
CAS:<p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>Fórmula:C102H172N36O32S7Pureza:98%Forma y color:White PowderPeso molecular:2639.13UK-59811 hydrochloride
CAS:<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Fórmula:C22H30BrClN2O5Forma y color:SolidPeso molecular:517.85Calcium Channel antagonist 3
CAS:<p>Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Fórmula:C23H26N2O4SPureza:>99.99%Forma y color:SolidPeso molecular:426.53Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Fórmula:C18H27N5OForma y color:SolidPeso molecular:329.448ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Fórmula:C106H178N40O32S7·C2HF3O2Forma y color:SolidPeso molecular:2863.27Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Fórmula:C29H33FN2O6Pureza:98.95% - 99.50%Forma y color:SolidPeso molecular:524.58Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Fórmula:C110H196N40O24S4Pureza:98%Forma y color:SolidPeso molecular:2591.25Calcium Channel antagonist 2
CAS:<p>Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.</p>Fórmula:C23H25FN2O4SPureza:99.34%Forma y color:SolidPeso molecular:444.52Calcium Channel antagonist 4
CAS:<p>Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Fórmula:C23H26N2O4SPureza:98.09%Forma y color:SolidPeso molecular:426.53Chlorocresol
CAS:<p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>Fórmula:C7H7ClOForma y color:SolidPeso molecular:142.58Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Forma y color:SolidPeso molecular:3310.112-Nitrobenzoic acid
CAS:<p>2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.</p>Fórmula:C7H5NO4Pureza:99.97%Forma y color:SoildPeso molecular:167.12ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Fórmula:C120H182N38O43S6Pureza:98%Forma y color:SolidPeso molecular:3037Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OForma y color:SolidPeso molecular:1224.18(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.472MMK 1
CAS:<p>Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.</p>Fórmula:C75H123N19O18SPureza:98%Forma y color:SolidPeso molecular:1610.97Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Forma y color:LiquidSulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Fórmula:C24H35Cl2N3O4SPureza:99.33% - 99.76%Forma y color:SoildPeso molecular:532.523Kurtoxin
<p>Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)</p>Fórmula:C324H478N94O90S8Pureza:98%Forma y color:SolidPeso molecular:7386.36SG-094
CAS:<p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>Fórmula:C30H29NO3Pureza:97.06%Forma y color:SoildPeso molecular:451.56Ethacrynic acid D5
CAS:<p>Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.</p>Fórmula:C13H12Cl2O4Pureza:98%Forma y color:SolidPeso molecular:308.17(R)-IDHP
CAS:<p>(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.</p>Fórmula:C12H16O5Forma y color:SolidPeso molecular:240.25KT-362 free base
CAS:<p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>Fórmula:C22H28N2O3SPureza:99.76%Forma y color:SoildPeso molecular:400.53Fasudil
CAS:<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Forma y color:SolidPeso molecular:291.37Ser-Ala-alloresact acetate
<p>Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.</p>Fórmula:C44H75N13O16S2Pureza:99.73%Forma y color:SolidPeso molecular:1106.281-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Fórmula:C5H10ClNO2Pureza:>99.99%Forma y color:SolidPeso molecular:151.59
