Transportador de monocarboxilato
Los transportadores de monocarboxilatos son proteínas de membrana que facilitan el transporte de monocarboxilatos, como lactato, piruvato y cuerpos cetónicos, a través de las membranas celulares. Estos transportadores juegan un papel crucial en los procesos metabólicos, especialmente en los tejidos que dependen del lactato y otros monocarboxilatos como fuentes de energía. Los MCT también están involucrados en la regulación del pH y están implicados en condiciones como el cáncer y los trastornos metabólicos. En CymitQuimica, ofrecemos una variedad de moduladores de MCT para apoyar su investigación en metabolismo, oncología y energética celular.
Se han encontrado 19 productos para "Transportador de monocarboxilato".
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AR-C155858
CAS:AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).Fórmula:C21H27N5O5SPureza:98.96% - 99.42%Forma y color:SolidPeso molecular:461.535AZ1422
AZ1422 is a selective MCT4 inhibitor, applicable for cancer research.Fórmula:C31H40N2O6Forma y color:SolidPeso molecular:536.28864α-Cyano-4-hydroxycinnamic acid-d4
CAS:α-Cyano-4-hydroxycinnamic acid-d4 (α-Cyano-4-hydroxycinnamate-d4) is the deuterium-labeled version of α-Cyano-4-hydroxycinnamic acid. As a potent non-competitive inhibitor of monocarboxylate transporters (MCTs), α-Cyano-4-hydroxycinnamic acid effectively impedes mitochondrial pyruvate transporters with a Ki value of 6.3 μM. It is also utilized as a matrix in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) to enhance peptide ionization.Fórmula:C10H7NO3Peso molecular:193.19AZD0095
CAS:AZD0095 is a selective inhibitor of MCT4 with an IC50 of 1.3 nM.Fórmula:C27H32N8O2Pureza:98.51%Forma y color:SoildPeso molecular:500.5954AR-C141990 hydrochloride
CAS:AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.Fórmula:C26H29ClN4O4SForma y color:SolidPeso molecular:529.05Lactate transportor 1
Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 μMPureza:98%Forma y color:Odour SolidMSC-4381
CAS:MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.Fórmula:C26H20ClN3O6SPureza:99.04% - 99.55%Forma y color:SolidPeso molecular:537.977ACC2
CAS:7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.Fórmula:C18H15NO4Pureza:99.19% - ≥95%Forma y color:Yellow SolidPeso molecular:309.3167ACC1
CAS:7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx.Fórmula:C14H15NO4Pureza:99.90%Forma y color:SolidPeso molecular:261.2732BAY-8002
CAS:BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).Fórmula:C20H14ClNO5SPureza:98.45% - 99.13%Forma y color:SolidPeso molecular:415.847Syrosingopine
CAS:Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.Fórmula:C35H42N2O11Pureza:99.25% - 99.78%Forma y color:White SolidPeso molecular:666.7148AZD3965
CAS:AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1).Fórmula:C21H24F3N5O5SPureza:98% - 99.90%Forma y color:White SolidPeso molecular:515.51α-Cyano-4-hydroxycinnamic acid
CAS:α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvateFórmula:C10H7NO3Pureza:98.96% - 99.82%Forma y color:SolidPeso molecular:189.1675VB124
CAS:VB124 is an orally active, potent and selective MCT4 inhibitor. VB124 blocked lactate importand expor in MDA-MB-231 cells.Cost-effective and quality-assured.Fórmula:C23H23ClN2O4Pureza:99.21% - 99.57%Forma y color:SoildPeso molecular:426.893MCT-IN-1
CAS:MCT-IN-1 (compound 2) acts as a potent inhibitor of the monocarboxylate transporter (MCT), demonstrating IC50 values of 9 nM for MCT1 and 14 nM for MCT4.Fórmula:C19H26N2O3Forma y color:SolidPeso molecular:330.42MCT1-IN-2
CAS:SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.Fórmula:C25H29N3O2SForma y color:SolidPeso molecular:435.58AR-C117977
CAS:AR-C117977: Potent MCT1 inhibitor, reduces immune response, extends graft survival, induces tolerance in vitro/in vivo.Fórmula:C25H28N2O3S2Forma y color:SolidPeso molecular:468.63MCT1-IN-3
CAS:MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor.Fórmula:C22H19N3O4Pureza:98.93%Forma y color:SoildPeso molecular:389.404AR-C141990
CAS:AR-C141990 is a lactate transporters inhibitor.Fórmula:C26H28N4O4SForma y color:SolidPeso molecular:492.59
