PDE
Las fosfodiesterasas (PDEs) son enzimas que hidrolizan nucleótidos cíclicos, como el AMPc y el GMPc, en sus formas inactivas, desempeñando un papel clave en la regulación de las vías de señalización intracelular. Los inhibidores de PDE se utilizan en el tratamiento de diversas afecciones, como enfermedades cardiovasculares, disfunción eréctil y trastornos respiratorios, debido a su capacidad para modular los niveles de nucleótidos cíclicos. En CymitQuimica, ofrecemos una gama de inhibidores de PDE para apoyar su investigación en señalización celular, farmacología y desarrollo terapéutico.
Se han encontrado 165 productos de "PDE"
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Amrinone
CAS:<p>Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.</p>Fórmula:C10H9N3OPureza:98.88% - 99.45%Forma y color:SolidPeso molecular:187.2N-Methylbenzamide
CAS:<p>N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.</p>Fórmula:C8H9NOPureza:99.83%Forma y color:Physical Description Off-White Crystalline Solid (Ntp 1992)Peso molecular:135.16Zatolmilast
CAS:<p>Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).</p>Fórmula:C21H15ClF3NO2Pureza:98.20%Forma y color:SolidPeso molecular:405.8Roflumilast
CAS:<p>Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential</p>Fórmula:C17H14Cl2F2N2O3Pureza:99.76% - 99.86%Forma y color:SolidPeso molecular:403.21Pumafentrine
CAS:<p>Pumafentrine（BY 343） is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.</p>Fórmula:C29H39N3O3Pureza:>99.99%Forma y color:SolidPeso molecular:477.64Cilostazol
CAS:<p>Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.</p>Fórmula:C20H27N5O2Pureza:99.58% - 99.90%Forma y color:Off-White SolidPeso molecular:369.46Pimobendan
CAS:<p>Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50: 0.32 μM).</p>Fórmula:C19H18N4O2Pureza:99.91%Forma y color:SolidPeso molecular:334.37ITI-214
CAS:<p>ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members, exhibits potent PDE1 inhibitory activity.</p>Fórmula:C29H29FN7O5PPureza:98.21%Forma y color:SolidPeso molecular:605.56T-0156
CAS:<p>T-0156 is a PEG5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4.</p>Fórmula:C31H29N5O7Pureza:98.53% - 98.76%Forma y color:SoildPeso molecular:583.59EMD57439
CAS:<p>EMD57439 is a selective PDE-III inhibitor, showing no significant increase in c-AMP concentration and producing little change in Ca(50).</p>Fórmula:C22H23N3O4SPureza:99.38% - 99.57%Forma y color:SolidPeso molecular:425.5NSP-805
CAS:<p>NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.</p>Fórmula:C17H19N3O2Pureza:99.85%Forma y color:SolidPeso molecular:297.35ATX inhibitor 1
CAS:<p>ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).</p>Fórmula:C21H23Cl2N2O6PPureza:99.52%Forma y color:SolidPeso molecular:501.3Carbodenafil
CAS:<p>Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).</p>Fórmula:C24H32N6O3Pureza:98.96% - 99.89%Forma y color:SolidPeso molecular:452.55Trapidil
CAS:<p>Trapidil (Avantrin) is a coronary vasodilator agent.</p>Fórmula:C10H15N5Pureza:99.42%Forma y color:SolidPeso molecular:205.26Milrinone
CAS:<p>Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.</p>Fórmula:C12H9N3OPureza:99.22% - 99.92%Forma y color:SolidPeso molecular:211.22MR-L2
CAS:<p>MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).</p>Fórmula:C19H16Cl3FN4OPureza:98.09% - 98.94%Forma y color:SolidPeso molecular:441.71PDE4B-IN-4
<p>PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.</p>Fórmula:C26H27N5O5Forma y color:SolidPeso molecular:489.52Acetildenafil
CAS:<p>Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.</p>Fórmula:C25H34N6O3Forma y color:Off-White To Pale Yelow SolidPeso molecular:466.58WAY-313170
CAS:<p>WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.</p>Fórmula:C19H17ClN2O2S2Pureza:99.3%Forma y color:SolidPeso molecular:404.93FCPR03
CAS:<p>FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.</p>Fórmula:C15H19F2NO3Pureza:99.94%Forma y color:SolidPeso molecular:299.31BC 11-38
CAS:<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Fórmula:C15H16N2OS2Pureza:98.95% - 99.28%Forma y color:SolidPeso molecular:304.43OPC18750 HCl
CAS:<p>OPC18750 HCl is a phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.</p>Fórmula:C20H23ClN2O4Pureza:98.92%Forma y color:SoildPeso molecular:390.86PDE10A-IN-5
<p>PDE10A-IN-5 (Compound A30) is an orally active inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 value of 3.5 nM. By inhibiting PDE10A, it activates the cyclic adenosine monophosphate (cAMP)-related signaling pathway, exhibiting activity against pulmonary vascular remodeling. This compound is applicable to research in the field of pulmonary arterial hypertension.</p>Forma y color:Odour SolidDazonone
CAS:<p>Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.</p>Fórmula:C11H10ClN3OPureza:99.54% - 99.73%Forma y color:SolidPeso molecular:235.67PDE5-IN-9
CAS:<p>WAY-639921 treats cardiovascular and respiratory conditions by inhibiting PDE1c.</p>Fórmula:C18H14N4SPureza:99.98%Forma y color:SolidPeso molecular:318.4Enpp-1-IN-14
CAS:<p>Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.</p>Fórmula:C15H22ClN5O4SPureza:99.83%Forma y color:SoildPeso molecular:403.88Oglemilast
CAS:<p>Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo.</p>Fórmula:C20H13Cl2F2N3O5SPureza:99.82%Forma y color:SolidPeso molecular:516.3BAY 2666605
CAS:<p>BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.</p>Fórmula:C17H12F4N2O2Pureza:99.81%Forma y color:SolidPeso molecular:352.28ONO-8430506
CAS:<p>ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.</p>Fórmula:C27H28FN3O3Pureza:98.34%Forma y color:SolidPeso molecular:461.53BI 1015550
CAS:<p>Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM.Cost-effective and quality-assured.</p>Fórmula:C20H25ClN6O2SPureza:98.06% - 99.71%Forma y color:SoildPeso molecular:448.97Arofylline
CAS:<p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>Fórmula:C14H13ClN4O2Pureza:98.19%Forma y color:SolidPeso molecular:304.73cis-Tadalafil
CAS:<p>Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.</p>Fórmula:C22H19N3O4Pureza:99.89%Forma y color:SolidPeso molecular:389.4UK 227786
CAS:<p>UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.</p>Fórmula:C22H22Cl2N4O4Pureza:99.9%Forma y color:SoildPeso molecular:477.34(1R,2R)-MK-8189
CAS:<p>(1R,2R)-MK-8189 is an isomer of MK-8189, a potent and selective pyrimidine PDE10A inhibitor.</p>Fórmula:C19H22N6OSPureza:>99.99% - >99.99%Forma y color:SoildPeso molecular:382.48Theodrenaline hydrochloride
CAS:<p>Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.</p>Fórmula:C17H22ClN5O5Pureza:98% - 98.18%Forma y color:SoildPeso molecular:411.84Anti-ALDH7A1 Antibody (3P955)
<p>Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.</p>Forma y color:Odour LiquidALDH7A1 Protein, Human, Recombinant (His)
<p>ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family.</p>Forma y color:Lyophilized PowderPeso molecular:56 kDa (predicted); 56 kDa (reducing conditions)PF-05180999
CAS:<p>α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.</p>Fórmula:C19H17F3N8Pureza:99.43% - 99.82%Forma y color:SolidPeso molecular:414.39Anti-ALDH7A1 Antibody-FITC (5P692)
<p>Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.</p>Forma y color:Odour LiquidBAY 73-6691 racemate
CAS:<p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>Fórmula:C15H12ClF3N4OForma y color:SolidPeso molecular:356.73Anti-ALDH7A1 Antibody (6G475)
<p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>Forma y color:Odour LiquidAutotaxin modulator 1
CAS:<p>Autotaxin modulator 1 is a new modulator of Autotaxin.</p>Fórmula:C28H31F6NO3Pureza:99.46%Forma y color:SolidPeso molecular:543.54ENPP1 Inhibitor C
CAS:<p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>Fórmula:C15H18N6Pureza:99.28%Forma y color:SolidPeso molecular:282.34Anti-ALDH7A1 Antibody (1G435)
<p>Anti-ALDH7A1 Antibody (1G435) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (1G435) can be used in ELISA.</p>Forma y color:Odour LiquidN-Ethyl tadalafil
CAS:<p>N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.</p>Fórmula:C23H21N3O4Pureza:99.58%Forma y color:SolidPeso molecular:403.43Anti-ALDH7A1 Antibody (5P692)
<p>Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.</p>Forma y color:Odour LiquidBay 60-7550
CAS:<p>Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.</p>Fórmula:C27H32N4O4Pureza:98.14%Forma y color:SolidPeso molecular:476.57PF-05085727
CAS:<p>PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.</p>Fórmula:C20H18F3N7Pureza:98%Forma y color:SolidPeso molecular:413.4THPP-1
CAS:<p>THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).</p>Fórmula:C23H21ClN6O3Pureza:99.46%Forma y color:SolidPeso molecular:464.9PF-8380
CAS:<p>PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).</p>Fórmula:C22H21Cl2N3O5Pureza:98.70% - 99.25%Forma y color:SolidPeso molecular:478.33PQ-10
CAS:<p>PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.</p>Fórmula:C22H21N5O3Pureza:99.86%Forma y color:SolidPeso molecular:403.43Roflumilast N-oxide
CAS:<p>Roflumilast N-oxide is an inhibitor of PDE type 4.</p>Fórmula:C17H14Cl2F2N2O4Pureza:98.19% - 99.69%Forma y color:SolidPeso molecular:419.21Balipodect
CAS:<p>Balipodect (TAK063) is a highly effective and selective PDE10A inhibitor (IC50: 0.30 nM); Its selectivity is >15000-fold over other PDEs.</p>Fórmula:C23H17FN6O2Pureza:98% - 99.79%Forma y color:SolidPeso molecular:428.42Irsogladine
CAS:<p>Irsogladine (Dicloguamine) is an anti-ulcer agent that promotes gap junction intercellular communication via M1 muscarinic acetylcholine receptor binding.</p>Fórmula:C9H7Cl2N5Pureza:99.74% - 99.91%Forma y color:White Or Colorless Crystal Or Crystalline Powder Odorless Slightly BitterPeso molecular:256.09K-Ras-PDEδ-IN-1
CAS:<p>K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).</p>Fórmula:C25H26FN5O2Pureza:99.48%Forma y color:SolidPeso molecular:447.5Cilomilast
CAS:<p>Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.</p>Fórmula:C20H25NO4Pureza:97.37% - 99.52%Forma y color:White SolidPeso molecular:343.42ICI 63197
CAS:<p>ICI 63197 (2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one) is a PDE4 inhibitor.</p>Fórmula:C9H13N5OPureza:99.70%Forma y color:White SolidPeso molecular:207.23IBMX
CAS:<p>IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM</p>Fórmula:C10H14N4O2Pureza:98% - >99.99%Forma y color:Off-WhitePeso molecular:222.242,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide
CAS:<p>2,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide is a PDE inhibitor.</p>Fórmula:C9H9Cl2F2NO3SPureza:98.60%Forma y color:SolidPeso molecular:320.14Olprinone
CAS:<p>Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuate</p>Fórmula:C14H10N4OPureza:99.68%Forma y color:SolidPeso molecular:250.26HA130
CAS:<p>HA130 is a selective ATX (autotaxin) inhibitor.</p>Fórmula:C24H19BFNO5SPureza:98.26% - ≥95%Forma y color:SolidPeso molecular:463.29Ro 20-1724
CAS:<p>Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1</p>Fórmula:C15H22N2O3Pureza:98.82% - 99.79%Forma y color:SolidPeso molecular:278.35Mardepodect
CAS:<p>Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE.</p>Fórmula:C25H20N4OPureza:99.81% - 99.94%Forma y color:SolidPeso molecular:392.45BW-A 78U
CAS:<p>BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.</p>Fórmula:C13H12FN5Pureza:99.45%Forma y color:SolidPeso molecular:257.27MBCQ
CAS:<p>MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.</p>Fórmula:C16H12ClN3O2Pureza:99.45%Forma y color:SolidPeso molecular:313.74HA 155
CAS:<p>HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.</p>Fórmula:C24H19BFNO5SPureza:99.88%Forma y color:SolidPeso molecular:463.29Ibudilast
CAS:<p>Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.</p>Fórmula:C14H18N2OPureza:99.83% - >99.99%Forma y color:White SolidPeso molecular:230.31ML-030
CAS:<p>ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.</p>Fórmula:C20H20N4O4SPureza:97.93%Forma y color:SolidPeso molecular:412.46SEP-0372814
CAS:<p>SEP-0372814 is a potent inhibitor of PDE10.</p>Fórmula:C21H19N7Pureza:99.29%Forma y color:SolidPeso molecular:369.42YM976
CAS:<p>YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)</p>Fórmula:C17H16ClN3OPureza:99.84%Forma y color:SolidPeso molecular:313.78Cilostamide
CAS:<p>Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)</p>Fórmula:C20H26N2O3Pureza:98.87%Forma y color:White To Off-White SolidPeso molecular:342.43D159687
CAS:<p>D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant benefit.</p>Fórmula:C21H19ClN2O2Pureza:97.57%Forma y color:SolidPeso molecular:366.84RS-25344 hydrochloride
CAS:<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Fórmula:C19H14ClN5O4Pureza:99.25%Forma y color:SolidPeso molecular:411.8BRL-50481
CAS:<p>BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 and 490 μM for PDE7A, PDE7B, PDE4 and PDE3, respectively.</p>Fórmula:C9H12N2O4SPureza:99.66%Forma y color:SolidPeso molecular:244.27Piclamilast
CAS:<p>Piclamilast (RP 73401) is a PDE4 inhibitor.</p>Fórmula:C18H18Cl2N2O3Pureza:98.28% - 99.57%Forma y color:SolidPeso molecular:381.25Ensifentrine
CAS:<p>Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that</p>Fórmula:C26H31N5O4Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:477.56Z-HA155
CAS:<p>Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.</p>Fórmula:C24H19BFNO5SPureza:99.18%Forma y color:SolidPeso molecular:463.29Crisaborole
CAS:<p>Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.</p>Fórmula:C14H10BNO3Pureza:99.70%Forma y color:SolidPeso molecular:251.05Udenafil
CAS:<p>Udenafil is an inhibitor of PDE5 .</p>Fórmula:C25H36N6O4SPureza:99.90%Forma y color:Off-White SolidPeso molecular:516.66GSK256066
CAS:<p>GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold</p>Fórmula:C27H26N4O5SPureza:99.60% - 99.66%Forma y color:SolidPeso molecular:518.58Nortadalafil
CAS:<p>Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.</p>Fórmula:C21H17N3O4Pureza:99.42%Forma y color:SolidPeso molecular:375.38Homo Sildenafil
CAS:<p>Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.</p>Fórmula:C23H32N6O4SPureza:99.88%Forma y color:White SolidPeso molecular:488.6GEBR-7b
CAS:<p>GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.</p>Fórmula:C13H16O3Pureza:99.533%Forma y color:SolidPeso molecular:220.26Enoximone
CAS:<p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>Fórmula:C12H12N2O2SPureza:98.53%Forma y color:SolidPeso molecular:248.3MY-5445
CAS:<p>MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).</p>Fórmula:C20H14ClN3Pureza:99.77%Forma y color:SolidPeso molecular:331.8Amino Tadalafil
CAS:<p>Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.</p>Fórmula:C21H18N4O4Pureza:99.85%Forma y color:White PowderPeso molecular:390.39Sildenafil Mesylate
CAS:<p>Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.</p>Fórmula:C22H30N6O4S·xCH4O3SPureza:99.84%Forma y color:SolidPeso molecular:570.68Lodenafil
CAS:<p>Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)</p>Fórmula:C23H32N6O5SPureza:99.92%Forma y color:SolidPeso molecular:504.6[11C]MP 10
CAS:<p>[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.</p>Fórmula:C25H20N4OPureza:99.5%Forma y color:SolidPeso molecular:391.45Osoresnontrine
CAS:<p>Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.</p>Fórmula:C16H17N5O2Pureza:99.93%Forma y color:SolidPeso molecular:311.34CP671305
CAS:<p>CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.</p>Fórmula:C23H19FN2O7Pureza:99.39%Forma y color:SolidPeso molecular:454.4Ziritaxestat
CAS:<p>Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.</p>Fórmula:C30H33FN8O2SPureza:97% - 99.85%Forma y color:SolidPeso molecular:588.7PDE10-IN-1
CAS:<p>PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.</p>Fórmula:C21H19N7Pureza:99.65%Forma y color:SolidPeso molecular:369.42RS-25344
CAS:<p>RS-25344: a strong PDE4 blocker, curbs eosinophil movement, boosts sperm motility in vitro.</p>Fórmula:C19H13N5O4Pureza:98.98%Forma y color:SolidPeso molecular:375.34Lotamilast
CAS:<p>Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.</p>Fórmula:C26H24N4O5Pureza:97.03% - 99.29%Forma y color:SolidPeso molecular:472.49Enpp-1-IN-1
CAS:<p>Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)</p>Fórmula:C17H17N3O3SPureza:97.52%Forma y color:SolidPeso molecular:343.4GSK256066 Trifluoroacetate
CAS:<p>GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.</p>Fórmula:C29H27F3N4O7SForma y color:SolidPeso molecular:632.61Crisaborole-d4
<p>Crisaborole-d4 (AN-2728-d4) is the deuterated form of Crisaborole. Crisaborole is a PDE4 inhibitor and also a cytokine release inhibitor.</p>Fórmula:C14H6D4BNO3Forma y color:SolidPeso molecular:255.07ent-Tadalafil
CAS:<p>ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).</p>Fórmula:C22H19N3O4Pureza:98%Forma y color:SolidPeso molecular:389.4Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Fórmula:C40H37N5OPureza:99.4%Forma y color:SolidPeso molecular:603.75
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