Glucoquinasa

Dorzagliatin is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell …

Oxfendazole, a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.

KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 …

MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is …

PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce …

Balanophonin shows potent α-glucosidase inhibitory activity, it has antioxidant, and anti-cancer activities. (±)-Balanophonin shows significant …

Guajadial shows α-glucosidase inhibitory activities significantly and its activity was better than that of Acarbose.Guajadial …

AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 …

Tangshenoside I might be a potential bioactive marker related to the hematopoietic and immunologic functions …

Tachioside has antiobesity, antioxidant and α-glucosidase inhibitory activities, it decreases lipid content in 3T3-L1 adipocytes …

ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 …

Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in …

ML266 is glucocerebrosidase (GCase) molecule chaperone, IC50 = 2.5 µM. ML266 binds to GCase and …

Pinoresinol diacetate inhibits the enzyme α-glucosidase in vitro and may therefore act as a hypoglycemic …

WAY-640509 is a glucocerebrosidase inhibitor.

Cyclomusalenone is a potent α-glucosidase inhibitor.

AP-III-a4 (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.

Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to …

PFK-158 is an effective and specific inhibitor PFKFB3.

PF-04937319 is an activator of glucokinase (EC50 =154.4 μM). PF-04937319 maintains glucose-lowering efficacy while mitigating …

AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the …

AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used …

Palmitelaidic Acid is one of the most abundant fatty acids in serum and tissue.

(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.

Kaempferitrin has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and …

AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).

3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several …

LY2608204 has been used in trials studying the treatment of Diabetes Mellitus, Type 2.

PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in …

Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as …

ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting …

PF-04991532 is an effective, hepatoselective glucokinase activator. It has EC50s of 80 and 100 nM …

Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).

KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 …

AMG-1694 is a potent glucokinase-glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the …