Glucoquinasa
La glucocinasa (GK) es una enzima que cataliza la fosforilación de la glucosa a glucosa-6-fosfato, un paso crítico en la glucólisis. La GK se expresa predominantemente en el hígado y el páncreas, donde desempeña un papel clave en la regulación de los niveles de glucosa en sangre. Los inhibidores de GK son de interés en el estudio de trastornos metabólicos como la diabetes, ya que pueden modular el metabolismo de la glucosa y la secreción de insulina. En CymitQuimica, ofrecemos inhibidores de glucocinasa para apoyar su investigación en diabetes, metabolismo y desarrollo terapéutico.
Se han encontrado 54 productos de "Glucoquinasa"
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AM-2394
CAS:<p>AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate.</p>Fórmula:C22H25N5O4Pureza:99.01% - 99.62%Forma y color:SolidPeso molecular:423.463PO
CAS:<p>3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.</p>Fórmula:C13H10N2OPureza:99.56% - 99.67%Forma y color:SolidPeso molecular:210.23Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Fórmula:C16H30O2Pureza:99.76%Forma y color:SolidPeso molecular:254.41(E)-3PO
CAS:<p>(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.</p>Fórmula:C13H10N2OPureza:98.8% - 98.92%Forma y color:SolidPeso molecular:210.23PFK-015
CAS:<p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>Fórmula:C17H12N2OPureza:99.7% - 99.85%Forma y color:SolidPeso molecular:260.29Genz-123346 free base
CAS:<p>Genz 123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1.</p>Fórmula:C24H38N2O4Pureza:99.41%Forma y color:SolidPeso molecular:418.57AMG-3969
CAS:<p>AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).</p>Fórmula:C21H20F6N4O3SPureza:99.65%Forma y color:SolidPeso molecular:522.46Glucokinase activator 1
CAS:<p>Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).</p>Fórmula:C27H20F2N2O7S2Pureza:98%Forma y color:SolidPeso molecular:586.58RO-28-1675
CAS:<p>RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.</p>Fórmula:C18H22N2O3S2Pureza:98.13%Forma y color:SolidPeso molecular:378.51PSN-GK1
CAS:<p>PSN-GK1 is a potent activator of glucokinase (EC50: 0.13 μM).</p>Fórmula:C20H23FN2O4S2Pureza:98%Forma y color:SolidPeso molecular:438.54GKA-22
CAS:<p>GKA-22 is a human glucokinase allosteric activator in the absence of glucose.</p>Fórmula:C22H22N2O5SPureza:98%Forma y color:SolidPeso molecular:426.49Piragliatin
CAS:<p>Piragliatin (RO4389620) activates glucokinase, boosts insulin, and lowers glucose in type 2 diabetes.</p>Fórmula:C19H20ClN3O4SForma y color:SolidPeso molecular:421.9IHVR-11029
CAS:<p>IHVR-11029 inhibits ER α-glucosidase, combats hemorrhagic fever viruses, and hinders enveloped virus morphogenesis.</p>Fórmula:C18H27F2NO5Forma y color:SolidPeso molecular:375.41GKA-71
CAS:<p>GKA-71 is an effective glucokinase activator (GKA).</p>Fórmula:C21H23N3O6S2Forma y color:SolidPeso molecular:477.55Glucokinase activator 3
CAS:<p>Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.</p>Fórmula:C26H33N2O9PS2Forma y color:SolidPeso molecular:612.65PF-04279405
CAS:<p>PF-04279405 is a potent and selective glucokinase activator.</p>Fórmula:C25H25FN4O4Forma y color:SolidPeso molecular:464.49Cefetrizole
CAS:<p>Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).</p>Fórmula:C16H15N5O4S3Pureza:98%Forma y color:SolidPeso molecular:437.52YZ9
CAS:<p>Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki of 0.094 µM[1].</p>Fórmula:C12H10O5Pureza:99.59%Forma y color:SolidPeso molecular:234.2AMG-1694
CAS:<p>AMG-1694 disrupts GK-GKRP complex, enhancing GK activity with 7 nM IC50; normalizes glucose in diabetic rodents without affecting normoglycemic animals.</p>Fórmula:C23H30F3N3O4S2Pureza:98.37%Forma y color:SolidPeso molecular:533.63AR453588
CAS:<p>AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H25N7O2S2Forma y color:SolidPeso molecular:519.64
