Aminopeptidasa
Las aminopeptidasas son un grupo de enzimas que catalizan la escisión de aminoácidos desde el extremo N-terminal de péptidos y proteínas, desempeñando un papel crucial en la maduración y degradación de proteínas. Estas enzimas están involucradas en varios procesos fisiológicos, incluyendo el procesamiento de antígenos, la regulación de hormonas peptídicas y la homeostasis celular. Los inhibidores de aminopeptidasas son de interés en el tratamiento de enfermedades como el cáncer, la inflamación y las enfermedades infecciosas. En CymitQuimica, ofrecemos una variedad de inhibidores de aminopeptidasas para apoyar su investigación en proteómica, desarrollo de medicamentos y tratamiento de enfermedades.
Se han encontrado 76 productos de "Aminopeptidasa"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ERAP1-IN-1
CAS:ERAP1-IN-1 inhibits and allosterically activates ERAP1, affecting fluorogenic, chromogenic, and nonamer peptide substrates.Fórmula:C20H21F3N2O5SPureza:98.95%Forma y color:SolidPeso molecular:458.45Ref: TM-T11221
1mg87,00€5mg170,00€10mg273,00€25mg449,00€50mg615,00€100mg843,00€200mg1.130,00€1mL*10mM (DMSO)170,00€Bufexamac
CAS:Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.Fórmula:C12H17NO3Pureza:99.73%Forma y color:Acicular CrystalPeso molecular:223.27Probestin
CAS:Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.Fórmula:C26H38N4O6Pureza:98%Forma y color:SolidPeso molecular:502.60Aminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Fórmula:C12H16F2N2O4SForma y color:SolidPeso molecular:322.07988BAY-277
BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).Fórmula:C44H52N8O5Forma y color:SolidPeso molecular:772.93LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>Leuhistin
CAS:Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.Fórmula:C11H19N3O3Pureza:98%Forma y color:White To Off-White SolidPeso molecular:241.29Matlystatin A
CAS:Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.Fórmula:C27H47N5O8SForma y color:SolidPeso molecular:601.76SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Fórmula:C18H16IN3O3Forma y color:SolidPeso molecular:449.24CD13-IN-1
<p>CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 value of 1.71 μM. It effectively suppresses the proliferation of various tumor cells, demonstrating antitumor activity.</p>Forma y color:Odour SolidAmastatin hydrochloride
CAS:Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.Fórmula:C21H39ClN4O8Forma y color:White To Off-White PowderPeso molecular:511.01ecMetAP-IN-1
CAS:ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。Fórmula:C13H11N3Pureza:99.34%Forma y color:SolidPeso molecular:209.25NGR peptide
CAS:Cell-penetrating peptideFórmula:C20H36N10O8S2Pureza:98%Forma y color:SolidPeso molecular:608.69JNJ-40929837 succinate
CAS:JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].Fórmula:C22H24N4O2S·xC4H6O4Forma y color:SolidBDM_92499
BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.Forma y color:Odour SolidAclimostat
CAS:Aclimostat (ZGN-1061) is a MetAP2 inhibitor with strong preclinical results, improving obesity-related metrics and gene expression.Fórmula:C26H42N2O6Forma y color:SolidPeso molecular:478.63Relzomostat
CAS:Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.Fórmula:C24H36F2N2O5Forma y color:SolidPeso molecular:470.558SDUY816
<p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>Fórmula:C18H16IN3O3Forma y color:SolidPeso molecular:449.24ERAP1-IN-3
ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.Fórmula:C22H22N2O4SForma y color:SolidPeso molecular:410.49Antho-rwamide I
CAS:Antho-rwamide I is an anthozoan neuropeptide.Fórmula:C31H46N10O7Forma y color:SolidPeso molecular:670.76
